FRMPD4 mutations cause X-linked intellectual disability and disrupt dendritic spine morphogenesis

Dendrite and spine modifications in autism and related neurodevelopmental disorders in patients and animal models

(2016) Verónica Martínez-Cerdeño   Developmental Neurobiology

Convergence of Hippocampal Pathophysiology in Syngap+/- and Fmr1-/y Mice

(2015) S. A. Barnes et al.   JOURNAL OF NEUROSCIENCE

X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes

(2015) H Hu et al.   MOLECULAR PSYCHIATRY

Affected Kindred Analysis of Human X Chromosome Exomes to Identify Novel X-Linked Intellectual Disability Genes

(2015) Tejasvi S. Niranjan et al.   PLoS One

Large-scale discovery of novel genetic causes of developmental disorders

(2014) T. W. Fitzgerald et al.   NATURE

Genome sequencing identifies major causes of severe intellectual disability

(2014) Christian Gilissen et al.   NATURE

XLID-Causing Mutations and Associated Genes Challenged in Light of Data From Large-Scale Human Exome Sequencing

(2013) Amélie Piton et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Prolyl-Isomerase Mediates Dopamine-Dependent Plasticity and Cocaine Motor Sensitization

(2013) Joo Min Park et al.   CELL

Loss of function of KIAA2022 causes mild to severe intellectual disability with an autism spectrum disorder and impairs neurite outgrowth

(2013) Lionel Van Maldergem et al.   HUMAN MOLECULAR GENETICS

Alterations to Dendritic Spine Morphology, but Not Dendrite Patterning, of Cortical Projection Neurons in Tc1 and Ts1Rhr Mouse Models of Down Syndrome

(2013) Matilda A. Haas et al.   PLoS One

GluA3-deficiency in mice is associated with increased social and aggressive behavior and elevated dopamine in striatum

(2012) Abby Adamczyk et al.   BEHAVIOURAL BRAIN RESEARCH

CDKL5 ensures excitatory synapse stability by reinforcing NGL-1–PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons

(2012) Sara Ricciardi et al.   NATURE CELL BIOLOGY

Preso1 dynamically regulates group I metabotropic glutamate receptors

(2012) Jia-Hua Hu et al.   NATURE NEUROSCIENCE

Diagnostic Exome Sequencing in Persons with Severe Intellectual Disability

(2012) Joep de Ligt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic and Epigenetic Networks in Intellectual Disabilities

(2011) Hans van Bokhoven   Annual Review of Genetics

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders

(2010) Y Ayhan et al.   MOLECULAR PSYCHIATRY

Homeostatic Scaling Requires Group I mGluR Activation Mediated by Homer1a

(2010) Jia-Hua Hu et al.   NEURON

Widespread changes in dendritic and axonal morphology inMecp2-mutant mouse models of rett syndrome: Evidence for disruption of neuronal networks

(2009) Pavel V. Belichenko et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Preso, A Novel PSD-95-Interacting FERM and PDZ Domain Protein That Regulates Dendritic Spine Morphogenesis

(2009) H. W. Lee et al.   JOURNAL OF NEUROSCIENCE

Rapid Functional Maturation of Nascent Dendritic Spines

(2009) Karen Zito et al.   NEURON

The PDZ and Band 4.1 Containing Protein Frmpd1 Regulates the Subcellular Location of Activator of G-protein Signaling 3 and Its Interaction with G-proteins

(2008) Ningfei An et al.   JOURNAL OF BIOLOGICAL CHEMISTRY