The activity of the serotonin receptor 2C is regulated by alternative splicing

RNA editing enzyme ADAR2 is a mediator of neuropathic pain after peripheral nerve injury

(2017) Hitoshi Uchida et al.   FASEB JOURNAL

Box C/D small nucleolar RNA genes and the Prader-Willi syndrome: a complex interplay

(2017) Jérôme Cavaillé   Wiley Interdisciplinary Reviews-RNA

Oligonucleotide‐induced alternative splicing of serotonin 2C receptor reduces food intake

(2016) Zhaiyi Zhang et al.   EMBO Molecular Medicine

An updated human snoRNAome

(2016) Hadi Jorjani et al.   NUCLEIC ACIDS RESEARCH

5-HT2C receptors in psychiatric disorders: A review

(2016) A. Chagraoui et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT2C receptor mediated appetite

(2016) Alastair S. Garfield et al.   Molecular Brain

Region-specific alterations of A-to-I RNA editing of serotonin 2c receptor in the cortex of suicides with major depression

(2016) D Weissmann et al.   Translational Psychiatry

Ghrelin’s Orexigenic Effect Is Modulated via a Serotonin 2C Receptor Interaction

(2015) Harriët Schellekens et al.   ACS Chemical Neuroscience

Lorcaserin Hcl for the treatment of obesity

(2015) Alpana P Shukla et al.   EXPERT OPINION ON PHARMACOTHERAPY

Identification of an RNA element for specific coordination of A-to-I RNA editing on HTR2C pre-mRNA

(2015) Masatora Fukuda et al.   GENES TO CELLS

Structure and function of serotonin G protein-coupled receptors

(2015) John D. McCorvy et al.   PHARMACOLOGY & THERAPEUTICS

Joint effect ofADARB1gene,HTR2Cgene and stressful life events on suicide attempt risk in patients with major psychiatric disorders

(2015) Jelena Karanović et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

To edit or not to edit: regulation of ADAR editing specificity and efficiency

(2015) Sarah N. Deffit et al.   Wiley Interdisciplinary Reviews-RNA

Decrease of mRNA Editing after Spinal Cord Injury is Caused by Down-regulation of ADAR2 that is Triggered by Inflammatory Response

(2015) Antonio Fabio Di Narzo et al.   Scientific Reports

A unique gene expression signature associated with serotonin 2C receptor RNA editing in the prefrontal cortex and altered in suicide

(2014) Antonio Fabio Di Narzo et al.   HUMAN MOLECULAR GENETICS

Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis

(2014) Eric D. Berglund et al.   JOURNAL OF CLINICAL INVESTIGATION

A 6-week randomized, double-blind, placebo-controlled, comparator referenced trial of vabicaserin in acute schizophrenia

(2014) Joan H.Q. Shen et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Controversies on the role of 5-HT2C receptors in the mechanisms of action of antidepressant drugs

(2014) Cedric B.P. Martin et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Differences between human wild-type and C23S variant 5-HT2C receptors in inverse agonist-induced resensitization

(2014) Jutta Walstab et al.   Pharmacological Reports

Antipsychotic Induced Weight Gain: Genetics, Epigenetics, and Biomarkers Reviewed

(2014) Tahireh A. Shams et al.   Current Psychiatry Reports

Enhancement of alcohol drinking in mice depends on alterations in RNA editing of serotonin 2C receptors

(2013) Yoshihisa Watanabe et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The time course of serotonin 2C receptor expression after spinal transection of rats: An immunohistochemical study

(2013) L.-Q. Ren et al.   NEUROSCIENCE

Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure

(2013) Manli Shen et al.   NUCLEIC ACIDS RESEARCH

Functional significance of serotonin receptor dimerization

(2013) Katharine Herrick-Davis   EXPERIMENTAL BRAIN RESEARCH

The 5′ untranslated region of the serotonin receptor 2C pre-mRNA generates miRNAs and is expressed in non-neuronal cells

(2013) Zhaiyi Zhang et al.   EXPERIMENTAL BRAIN RESEARCH

Promiscuous Dimerization of the Growth Hormone Secretagogue Receptor (GHS-R1a) Attenuates Ghrelin-mediated Signaling

(2012) Harriët Schellekens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Striatal Dopamine Release and Genetic Variation of the Serotonin 2C Receptor in Humans

(2012) B. J. Mickey et al.   JOURNAL OF NEUROSCIENCE

RNA splicing and editing modulation of 5-HT2C receptor function: relevance to anxiety and aggression in VGV mice

(2012) C B P Martin et al.   MOLECULAR PSYCHIATRY

Serotonin 2C receptor alternative splicing in a spinal cord injury model

(2012) Aya Nakae et al.   NEUROSCIENCE LETTERS

Dynamic 5-HT2C Receptor Editing in a Mouse Model of Obesity

(2012) Harriët Schellekens et al.   PLoS One

Dependencies among Editing Sites in Serotonin 2C Receptor mRNA

(2012) Liran Carmel et al.   PLoS Computational Biology

Effects of gabapentin on muscle spasticity and both induced as well as spontaneous autonomic dysreflexia after complete spinal cord injury

(2012) Alexander G. Rabchevsky et al.   Frontiers in Physiology

Pin1 and WWP2 regulateGluR2Q/R site RNA editing by ADAR2 with opposing effects

(2011) Roberto Marcucci et al.   EMBO JOURNAL

Antidepressant Treatments Change 5-HT2C Receptor mRNA Expression in Rat Prefrontal/Frontal Cortex and Hippocampus

(2011) Alessandro Barbon et al.   NEUROPSYCHOBIOLOGY

Alterations of serotonin 2C and 2A receptors in response to T10 spinal cord transection in rats

(2011) Scott Navarrett et al.   NEUROSCIENCE LETTERS

Latest Approaches for the Treatment of Spasticity and Autonomic Dysreflexia in Chronic Spinal Cord Injury

(2011) Alexander G. Rabchevsky et al.   Neurotherapeutics

Direct cloning of double-stranded RNAs from RNase protection analysis reveals processing patterns of C/D box snoRNAs and provides evidence for widespread antisense transcript expression

(2011) Manli Shen et al.   NUCLEIC ACIDS RESEARCH

Serotonin control of sleep-wake behavior

(2011) Jaime M. Monti   SLEEP MEDICINE REVIEWS

The snoRNA MBII-52 (SNORD 115) is processed into smaller RNAs and regulates alternative splicing

(2010) Shivendra Kishore et al.   HUMAN MOLECULAR GENETICS

5-HT2C receptor activation prevents stress-induced enhancement of brain 5-HT turnover and extracellular levels in the mouse brain: modulation by chronic paroxetine treatment

(2010) Raymond Mongeau et al.   JOURNAL OF NEUROCHEMISTRY

Locomotion After Spinal Cord Injury Depends on Constitutive Activity in Serotonin Receptors

(2010) K. Fouad et al.   JOURNAL OF NEUROPHYSIOLOGY

Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors

(2010) Katherine C Murray et al.   NATURE MEDICINE

Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader–Willi syndrome

(2010) Michael V. Morabito et al.   NEUROBIOLOGY OF DISEASE

Selective inhibition of ADAR2-catalyzed editing of the serotonin 2c receptor pre-mRNA by a helix-threading peptide

(2010) Nicole T. Schirle et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The design of barriers in the hypothalamus allows the median eminence and the arcuate nucleus to enjoy private milieus: The former opens to the portal blood and the latter to the cerebrospinal fluid

(2010) Esteban M. Rodríguez et al.   PEPTIDES

The roles of phospholipase C activation and alternative ADAR1 and ADAR2 pre-mRNA splicing in modulating serotonin 2C-receptor editing in vivo

(2010) C. Schmauss et al.   RNA

Identification of novel ribonucleo-protein complexes from the brain-specific snoRNA MBII-52

(2010) Y. Soeno et al.   RNA

Abnormal Behavior in a Chromosome- Engineered Mouse Model for Human 15q11-13 Duplication Seen in Autism

(2009) Jin Nakatani et al.   CELL

Promoter and functional polymorphisms of HTR2C and suicide victims

(2009) Alja Videtič et al.   GENES BRAIN AND BEHAVIOR

Altered serotonin 2C receptor RNA splicing in suicide: association with editing

(2009) Stella Dracheva et al.   NEUROREPORT

Ligand sensitivity in dimeric associations of the serotonin 5HT2c receptor

(2008) Filippo Mancia et al.   EMBO REPORTS

Lack of association between three serotonin genes and suicidal behavior in Chinese psychiatric patients

(2007) Jing Zhang et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY