Metabolic reprogramming ensures cancer cell survival despite oncogenic signaling blockade
出版年份 2017 全文链接
标题
Metabolic reprogramming ensures cancer cell survival despite oncogenic signaling blockade
作者
关键词
-
出版物
GENES & DEVELOPMENT
Volume 31, Issue 20, Pages 2067-2084
出版商
Cold Spring Harbor Laboratory
发表日期
2017-11-15
DOI
10.1101/gad.305292.117
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Momelotinib in myelofibrosis: JAK1/2 inhibitor with a role in treating and understanding the anemia
- (2017) Elliott F Winton et al. Future Oncology
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- (2016) Daniel J Klionsky et al. Autophagy
- Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer
- (2016) Justin M. Drake et al. CELL
- Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton
- (2016) Hai Hu et al. CELL
- Mapping the Human Platelet Lipidome Reveals Cytosolic Phospholipase A2 as a Regulator of Mitochondrial Bioenergetics during Activation
- (2016) David A. Slatter et al. Cell Metabolism
- New Strategies in Myeloproliferative Neoplasms: The Evolving Genetic and Therapeutic Landscape
- (2016) A. B. Patel et al. CLINICAL CANCER RESEARCH
- Pharmacology in the Era of Targeted Therapies: The Case of PI3K Inhibitors
- (2016) E. Toska et al. CLINICAL CANCER RESEARCH
- Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer
- (2016) Roman Camarda et al. NATURE MEDICINE
- mTORC1 and mTORC2 in cancer and the tumor microenvironment
- (2016) L C Kim et al. ONCOGENE
- Targeting BCL-2 and ABL/LYN in Philadelphia chromosome–positive acute lymphoblastic leukemia
- (2016) Jessica T. Leonard et al. Science Translational Medicine
- Therapeutic Targeting of Autophagy
- (2016) Christina G. Towers et al. EBioMedicine
- Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis
- (2015) J. E. Maxson et al. CANCER RESEARCH
- Fatty Acid Trafficking in Starved Cells: Regulation by Lipid Droplet Lipolysis, Autophagy, and Mitochondrial Fusion Dynamics
- (2015) Angelika S. Rambold et al. DEVELOPMENTAL CELL
- Autophagy in malignant transformation and cancer progression
- (2015) L. Galluzzi et al. EMBO JOURNAL
- High-throughput screening approaches to identify regulators of mammalian autophagy
- (2015) Justin Joachim et al. METHODS
- Ruxolitinib versus Standard Therapy for the Treatment of Polycythemia Vera
- (2015) Alessandro M. Vannucchi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Emerging strategies to effectively target autophagy in cancer
- (2015) V W Rebecca et al. ONCOGENE
- Detachment-induced autophagy duringanoikisand lumen formation in epithelial acini
- (2014) Jayanta Debnath Autophagy
- A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme
- (2014) Myrna R Rosenfeld et al. Autophagy
- First-in-Human Phase I Study of Pictilisib (GDC-0941), a Potent Pan-Class I Phosphatidylinositol-3-Kinase (PI3K) Inhibitor, in Patients with Advanced Solid Tumors
- (2014) D. Sarker et al. CLINICAL CANCER RESEARCH
- You eat what you are: autophagy inhibition as a therapeutic strategy in leukemia
- (2014) A R Sehgal et al. LEUKEMIA
- PI3K and cancer: lessons, challenges and opportunities
- (2014) David A. Fruman et al. NATURE REVIEWS DRUG DISCOVERY
- PhosphoSitePlus, 2014: mutations, PTMs and recalibrations
- (2014) Peter V. Hornbeck et al. NUCLEIC ACIDS RESEARCH
- Perilipins: Lipid droplet coat proteins adapted for tissue-specific energy storage and utilization, and lipid cytoprotection
- (2013) Carole Sztalryd et al. BIOCHIMIE
- Cell Survival during Complete Nutrient Deprivation Depends on Lipid Droplet-fueled β-Oxidation of Fatty Acids
- (2013) Ainara G. Cabodevilla et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The biophysics and cell biology of lipid droplets
- (2013) Abdou Rachid Thiam et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Oncogenic CSF3R Mutations in Chronic Neutrophilic Leukemia and Atypical CML
- (2013) Julia E. Maxson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phosphoproteomic Analysis Implicates the mTORC2-FoxO1 Axis in VEGF Signaling and Feedback Activation of Receptor Tyrosine Kinases
- (2013) G. Zhuang et al. Science Signaling
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- A Phase I Study of Erlotinib and Hydroxychloroquine in Advanced Non–Small-Cell Lung Cancer
- (2012) Sarah B. Goldberg et al. Journal of Thoracic Oncology
- AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress
- (2012) Sang-Min Jeon et al. NATURE
- A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis
- (2012) Srdan Verstovsek et al. NEW ENGLAND JOURNAL OF MEDICINE
- Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression
- (2012) J. M. Drake et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PI3K, Metabolic, and Autophagy Networks: Interactive Partners in Cellular Health and Disease
- (2011) Naval P. Shanware et al. Annual Review of Pharmacology and Toxicology
- Transcriptional Control of Cellular Metabolism by mTOR Signaling
- (2011) J. L. Yecies et al. CANCER RESEARCH
- Principles and Current Strategies for Targeting Autophagy for Cancer Treatment
- (2011) R. K. Amaravadi et al. CLINICAL CANCER RESEARCH
- First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
- (2011) Timothy A. Yap et al. JOURNAL OF CLINICAL ONCOLOGY
- Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment
- (2011) Jürgen Cox et al. JOURNAL OF PROTEOME RESEARCH
- Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids
- (2011) Jonathan Z Long et al. Nature Chemical Biology
- Glycolytic network restructuring integral to the energetics of embryonic stem cell cardiac differentiation
- (2010) Susan Chung et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Effects of Varespladib Methyl on Biomarkers and Major Cardiovascular Events in Acute Coronary Syndrome Patients
- (2010) Robert S. Rosenson et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
- (2010) Katrin Düvel et al. MOLECULAR CELL
- Recent progress in phospholipase A2 research: From cells to animals to humans
- (2010) Makoto Murakami et al. PROGRESS IN LIPID RESEARCH
- Akt-RSK-S6 Kinase Signaling Networks Activated by Oncogenic Receptor Tyrosine Kinases
- (2010) A. Moritz et al. Science Signaling
- Lipid homeostasis, lipotoxicity and the metabolic syndrome
- (2009) Roger H. Unger et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Characterization of Rictor Phosphorylation Sites Reveals Direct Regulation of mTOR Complex 2 by S6K1
- (2009) C. C. Dibble et al. MOLECULAR AND CELLULAR BIOLOGY
- mTORC1-Activated S6K1 Phosphorylates Rictor on Threonine 1135 and Regulates mTORC2 Signaling
- (2009) L.-A. Julien et al. MOLECULAR AND CELLULAR BIOLOGY
- Enhancing CD8 T-cell memory by modulating fatty acid metabolism
- (2009) Erika L. Pearce et al. NATURE
- Autophagy regulates lipid metabolism
- (2009) Rajat Singh et al. NATURE
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- A Molecule Targeting VHL-Deficient Renal Cell Carcinoma that Induces Autophagy
- (2008) Sandra Turcotte et al. CANCER CELL
- The Role of Autophagy in Mammalian Development: Cell Makeover Rather than Cell Death
- (2008) Francesco Cecconi et al. DEVELOPMENTAL CELL
- AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
- (2008) Dana M. Gwinn et al. MOLECULAR CELL
- Pyruvate kinase M2 is a phosphotyrosine-binding protein
- (2008) Heather R. Christofk et al. NATURE
- MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
- (2008) Jürgen Cox et al. NATURE BIOTECHNOLOGY
- Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
- (2008) Da Wei Huang et al. NUCLEIC ACIDS RESEARCH
- Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival
- (2007) Christopher Fung et al. MOLECULAR BIOLOGY OF THE CELL
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started