The biophysics and cell biology of lipid droplets

FSP27 and PLIN1 interaction promotes the formation of large lipid droplets in human adipocytes

(2013) Tan Hooi Min Grahn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Triacylglycerol Synthesis Enzymes Mediate Lipid Droplet Growth by Relocalizing from the ER to Lipid Droplets

(2013) Florian Wilfling et al.   DEVELOPMENTAL CELL

Balancing the fat: lipid droplets and human disease

(2013) Natalie Krahmer et al.   EMBO Molecular Medicine

Biochemistry and pathophysiology of intravascular and intracellular lipolysis

(2013) S. G. Young et al.   GENES & DEVELOPMENT

Protein Correlation Profiles Identify Lipid Droplet Proteins with High Confidence

(2013) Natalie Krahmer et al.   MOLECULAR & CELLULAR PROTEOMICS

COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp function

(2013) A. R. Thiam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover

(2013) James A. Olzmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytes

(2013) Zhiqi Sun et al.   Nature Communications

Lipid Droplets and Cellular Lipid Metabolism

(2012) Tobias C. Walther et al.   Annual Review of Biochemistry

Advanced Nanoemulsions

(2012) Michael M. Fryd et al.   Annual Review of Physical Chemistry

Apolipoprotein C-I Binds More Strongly to Phospholipid/Triolein/Water than Triolein/Water Interfaces: A Possible Model for Inhibiting Cholesterol Ester Transfer Protein Activity and Triacylglycerol-Rich Lipoprotein Uptake

(2012) Nathan L. Meyers et al.   BIOCHEMISTRY

Lipid Droplets Control the Maternal Histone Supply of Drosophila Embryos

(2012) Zhihuan Li et al.   CURRENT BIOLOGY

Remodeling of Lipid Droplets during Lipolysis and Growth in Adipocytes

(2012) Margret Paar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A 22-mer Segment in the Structurally Pliable Regulatory Domain of Metazoan CTP: Phosphocholine Cytidylyltransferase Facilitates Both Silencing and Activating Functions

(2012) Ziwei Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Studies on the Substrate and Stereo/Regioselectivity of Adipose Triglyceride Lipase, Hormone-sensitive Lipase, and Diacylglycerol-O-acyltransferases

(2012) Thomas O. Eichmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Perilipin family members preferentially sequester to either triacylglycerol-specific or cholesteryl-ester-specific intracellular lipid storage droplets

(2012) Kai Hsieh et al.   JOURNAL OF CELL SCIENCE

Seipin: from human disease to molecular mechanism

(2012) Bethany R. Cartwright et al.   JOURNAL OF LIPID RESEARCH

The N-terminal region of acyl-CoA synthetase 3 is essential for both the localization on lipid droplets and the function in fatty acid uptake

(2012) Margarete Poppelreuther et al.   JOURNAL OF LIPID RESEARCH

Wetting-Induced Budding of Vesicles in Contact with Several Aqueous Phases

(2012) Yanhong Li et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Concentration Dependence of the Interfacial Tension for Aqueous Two-Phase Polymer Solutions of Dextran and Polyethylene Glycol

(2012) Yonggang Liu et al.   LANGMUIR

From Stability to Permeability of Adhesive Emulsion Bilayers

(2012) Abdou R. Thiam et al.   LANGMUIR

Postlipolytic insulin-dependent remodeling of micro lipid droplets in adipocytes

(2012) Nicholas Ariotti et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane bending by protein–protein crowding

(2012) Jeanne C. Stachowiak et al.   NATURE CELL BIOLOGY

Exploring emulsion science with microfluidics

(2012) Nicolas Bremond et al.   Soft Matter

Lipid Droplet De Novo Formation and Fission Are Linked to the Cell Cycle in Fission Yeast

(2012) Allan P. Long et al.   TRAFFIC

Regulation of Lipid Droplet Cholesterol Efflux From Macrophage Foam Cells

(2011) Mireille Ouimet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

C-Terminus of Apolipoprotein A-I Removes Phospholipids from a Triolein/Phospholipids/Water Interface, but the N-Terminus Does Not: A Possible Mechanism for Nascent HDL Assembly

(2011) Matthew A. Mitsche et al.   BIOPHYSICAL JOURNAL

Autophagy in Hypothalamic AgRP Neurons Regulates Food Intake and Energy Balance

(2011) Susmita Kaushik et al.   Cell Metabolism

Phosphatidylcholine Synthesis for Lipid Droplet Expansion Is Mediated by Localized Activation of CTP:Phosphocholine Cytidylyltransferase

(2011) Natalie Krahmer et al.   Cell Metabolism

Packaging of Fat: An Evolving Model of Lipid Droplet Assembly and Expansion

(2011) Dawn L. Brasaemle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual Role of Ancient Ubiquitous Protein 1 (AUP1) in Lipid Droplet Accumulation and Endoplasmic Reticulum (ER) Protein Quality Control

(2011) Elizabeth J. Klemm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fsp27 promotes lipid droplet growth by lipid exchange and transfer at lipid droplet contact sites

(2011) Jingyi Gong et al.   JOURNAL OF CELL BIOLOGY

Lipid droplets are functionally connected to the endoplasmic reticulum in Saccharomyces cerevisiae

(2011) N. Jacquier et al.   JOURNAL OF CELL SCIENCE

A role for autophagy during hepatic stellate cell activation

(2011) Lien F.R. Thoen et al.   JOURNAL OF HEPATOLOGY

Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria

(2011) Hong Wang et al.   JOURNAL OF LIPID RESEARCH

Surfactants in droplet-based microfluidics

(2011) Jean-Christophe Baret   LAB ON A CHIP

Adhesive Emulsion Bilayers under an Electric Field: From Unzipping to Fusion

(2011) Abdou R. Thiam et al.   PHYSICAL REVIEW LETTERS

FSP27 Promotes Lipid Droplet Clustering and Then Fusion to Regulate Triglyceride Accumulation

(2011) Srikarthika Jambunathan et al.   PLoS One

Droplet-induced budding transitions of membranes

(2011) Halim Kusumaatmaja et al.   Soft Matter

Seipin, adipogenesis and lipid droplets

(2011) Weihua Fei et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

COPI Budding within the Golgi Stack

(2011) V. Popoff et al.   Cold Spring Harbor Perspectives in Biology

Not Just Fat: The Structure and Function of the Lipid Droplet

(2011) T. Fujimoto et al.   Cold Spring Harbor Perspectives in Biology

A Role for Phosphatidic Acid in the Formation of “Supersized” Lipid Droplets

(2011) Weihua Fei et al.   PLoS Genetics

Lipid droplets: A dynamic organelle moves into focus

(2010) Mathias Beller et al.   FEBS LETTERS

Ancient Ubiquitous Protein 1 (AUP1) Localizes to Lipid Droplets and Binds the E2 Ubiquitin Conjugase G2 (Ube2g2) via Its G2 Binding Region

(2010) Johanna Spandl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sterol-induced Dislocation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase from Endoplasmic Reticulum Membranes into the Cytosol through a Subcellular Compartment Resembling Lipid Droplets

(2010) Isamu Z. Hartman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipid demixing and the birth of a lipid droplet

(2010) J. Zanghellini et al.   JOURNAL OF THEORETICAL BIOLOGY

Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1

(2010) Eva Herker et al.   NATURE MEDICINE

Triglyceride Blisters in Lipid Bilayers: Implications for Lipid Droplet Biogenesis and the Mobile Lipid Signal in Cancer Cell Membranes

(2010) Himanshu Khandelia et al.   PLoS One

Quantitative Analysis of Lipid Droplet Fusion: Inefficient Steady State Fusion but Rapid Stimulation by Chemical Fusogens

(2010) Samantha Murphy et al.   PLoS One

Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores

(2010) Achim Lass et al.   PROGRESS IN LIPID RESEARCH

Lipid Droplet Biogenesis Induced by Stress Involves Triacylglycerol Synthesis That Depends on Group VIA Phospholipase A2

(2009) Albert Gubern et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coatomer-dependent protein delivery to lipid droplets

(2009) K. G. Soni et al.   JOURNAL OF CELL SCIENCE

Influence of surfactant structure on the contribution of micelles to Ostwald ripening in oil-in-water emulsions

(2009) Suwimon Ariyaprakai et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

On the Possible Role of Surface Elasticity in Emulsion Stability

(2009) Daniela Georgieva et al.   LANGMUIR

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Breaking of an Emulsion under an ac Electric Field

(2009) Abdou R. Thiam et al.   PHYSICAL REVIEW LETTERS

The antiviral protein, viperin, localizes to lipid droplets via its N-terminal amphipathic  -helix

(2009) E. R. Hinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophage cholesteryl ester mobilization and atherosclerosis

(2009) Shobha Ghosh et al.   VASCULAR PHARMACOLOGY

Fate of fat: The role of adipose triglyceride lipase in lipolysis

(2008) Robert Zimmermann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cell biology of lipid droplets

(2008) Christoph Thiele et al.   CURRENT OPINION IN CELL BIOLOGY

Contribution of Each Membrane Binding Domain of the CTP:Phosphocholine Cytidylyltransferase-α Dimer to Its Activation, Membrane Binding, and Membrane Cross-bridging

(2008) Svetla Taneva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cholesterol Promotes Hemifusion and Pore Widening in Membrane Fusion Induced by Influenza Hemagglutinin

(2008) Subrata Biswas et al.   JOURNAL OF GENERAL PHYSIOLOGY

Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores

(2008) Rudolf Zechner et al.   JOURNAL OF LIPID RESEARCH

Double Emulsion Templated Monodisperse Phospholipid Vesicles

(2008) Ho Cheung Shum et al.   LANGMUIR

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS

Decompressing Emulsion Droplets Favors Coalescence

(2008) Nicolas Bremond et al.   PHYSICAL REVIEW LETTERS