The punctilious RNA polymerase II core promoter

The human initiator is a distinct and abundant element that is precisely positioned in focused core promoters

(2017) Long Vo ngoc et al.   GENES & DEVELOPMENT

Promoter shape varies across populations and affects promoter evolution and expression noise

(2017) Ignacio E Schor et al.   NATURE GENETICS

Genome-wide uniformity of human ‘open’ pre-initiation complexes

(2016) William K.M. Lai et al.   GENOME RESEARCH

Molecular Mechanisms of Transcription Initiation—Structure, Function, and Evolution of TFE/TFIIE-Like Factors and Open Complex Formation

(2016) Fabian Blombach et al.   JOURNAL OF MOLECULAR BIOLOGY

Label-Free Relative Quantitation of Isobaric and Isomeric Human Histone H2A and H2B Variants by Fourier Transform Ion Cyclotron Resonance Top-Down MS/MS

(2016) Xibei Dang et al.   JOURNAL OF PROTEOME RESEARCH

Structure of promoter-bound TFIID and model of human pre-initiation complex assembly

(2016) Robert K. Louder et al.   NATURE

The core promoter: At the heart of gene expression

(2015) Yehuda M. Danino et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Structure-Function Analysis of theDrosophila melanogasterCaudal Transcription Factor Provides Insights into Core Promoter-preferential Activation

(2015) Hila Shir-Shapira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bidirectional Transcription Arises from Two Distinct Hubs of Transcription Factor Binding and Active Chromatin

(2015) Benjamin S. Scruggs et al.   MOLECULAR CELL

Perspectives on Unidirectional versus Divergent Transcription

(2015) Sascha H.C. Duttke et al.   MOLECULAR CELL

Human Gene Promoters Are Intrinsically Bidirectional

(2015) Robin Andersson et al.   MOLECULAR CELL

Human Promoters Are Intrinsically Directional

(2015) Sascha H.C. Duttke et al.   MOLECULAR CELL

Function and information content of DNA methylation

(2015) Dirk Schübeler   NATURE

Structural basis of transcription initiation by RNA polymerase II

(2015) Sarah Sainsbury et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DTIE, a novel core promoter element that directs start site selection in TATA-less genes

(2015) Nadav Marbach-Bar et al.   NUCLEIC ACIDS RESEARCH

MPE-seq, a new method for the genome-wide analysis of chromatin structure

(2015) Haruhiko Ishii et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution and diversification of the basal transcription machinery

(2015) Sascha H.C. Duttke   TRENDS IN BIOCHEMICAL SCIENCES

Core promoters in transcription: old problem, new insights

(2015) Ananda L. Roy et al.   TRENDS IN BIOCHEMICAL SCIENCES

A specific E3 ligase/deubiquitinase pair modulates TBP protein levels during muscle differentiation

(2015) Li Li et al.   eLife

DrosophilaTRF2 is a preferential core promoter regulator

(2014) Adi Kedmi et al.   GENES & DEVELOPMENT

TRF2 and the evolution of the bilateria

(2014) Sascha H.C. Duttke et al.   GENES & DEVELOPMENT

TRF2, but not TBP, mediates the transcription of ribosomal protein genes

(2014) Y.-L. Wang et al.   GENES & DEVELOPMENT

Core Promoter Functions in the Regulation of Gene Expression ofDrosophilaDorsal Target Genes

(2014) Yonathan Zehavi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA Polymerase III Accurately Initiates Transcription from RNA Polymerase II Promotersin Vitro

(2014) Sascha H. C. Duttke   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhancer–core-promoter specificity separates developmental and housekeeping gene regulation

(2014) Muhammad A. Zabidi et al.   NATURE

SRA- and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation

(2014) Lianna M. Johnson et al.   NATURE

Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers

(2014) Leighton J Core et al.   NATURE GENETICS

The SET Domain Proteins SUVH2 and SUVH9 Are Required for Pol V Occupancy at RNA-Directed DNA Methylation Loci

(2014) Zhang-Wei Liu et al.   PLoS Genetics

Divergent Transcription: A Driving Force for New Gene Origination?

(2013) Xuebing Wu et al.   CELL

Human TFIID Binds to Core Promoter DNA in a Reorganized Structural State

(2013) Michael A. Cianfrocco et al.   CELL

H3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation

(2013) Shannon M. Lauberth et al.   CELL

Differential Utilization of TATA Box-binding Protein (TBP) and TBP-related Factor 1 (TRF1) at Different Classes of RNA Polymerase III Promoters

(2013) Neha Verma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcription Start Site Evolution in Drosophila

(2013) Bradley J. Main et al.   MOLECULAR BIOLOGY AND EVOLUTION

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription

(2013) Michael T. Y. Lam et al.   NATURE

Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1

(2013) Julie A. Law et al.   NATURE

Taf7l cooperates with Trf2 to regulate spermiogenesis

(2013) H. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DTF1 is a core component of RNA-directed DNA methylation and may assist in the recruitment of Pol IV

(2013) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linking Stochastic Fluctuations in Chromatin Structure and Gene Expression

(2013) Christopher R. Brown et al.   PLOS BIOLOGY

Condensin controls recruitment of RNA polymerase II to achieve nematode X-chromosome dosage compensation

(2013) William S Kruesi et al.   eLife

Metazoan promoters: emerging characteristics and insights into transcriptional regulation

(2012) Boris Lenhard et al.   NATURE REVIEWS GENETICS

Core promoter-selective function of HMGA1 and Mediator in Initiator-dependent transcription

(2011) M. Xu et al.   GENES & DEVELOPMENT

CpG islands and the regulation of transcription

(2011) A. M. Deaton et al.   GENES & DEVELOPMENT

Multisubunit RNA polymerases IV and V: purveyors of non-coding RNA for plant gene silencing

(2011) Jeremy R. Haag et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TBP-related factors: a paradigm of diversity in transcription initiation

(2011) Waseem Akhtar et al.   Cell and Bioscience

Perspectives on the RNA polymerase II core promoter

(2011) James T. Kadonaga   Wiley Interdisciplinary Reviews-Developmental Biology

The TCT motif, a key component of an RNA polymerase II transcription system for the translational machinery

(2010) T. J. Parry et al.   GENES & DEVELOPMENT

Genome-wide analysis of promoter architecture in Drosophila melanogaster

(2010) R. A. Hoskins et al.   GENOME RESEARCH

Three Key Subregions Contribute to the Function of the Downstream RNA Polymerase II Core Promoter

(2010) J. W. M. Theisen et al.   MOLECULAR AND CELLULAR BIOLOGY

Tomio Tada 1934–2010

(2010) Masaru Taniguchi   NATURE IMMUNOLOGY

Three Novel Downstream Promoter Elements Regulate MHC Class I Promoter Activity in Mammalian Cells

(2010) Namhoon Lee et al.   PLoS One

Selective interaction between Trf3 and Taf3 required for early development and hematopoiesis

(2009) Daniel O. Hart et al.   DEVELOPMENTAL DYNAMICS

TBP2 is essential for germ cell development by regulating transcription and chromatin condensation in the oocyte

(2009) E. Gazdag et al.   GENES & DEVELOPMENT

High Throughput Characterization of Combinatorial Histone Codes

(2009) Nicolas L. Young et al.   MOLECULAR & CELLULAR PROTEOMICS

H3.3/H2A.Z double variant–containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions

(2009) Chunyuan Jin et al.   NATURE GENETICS

Characterization of Transcription from TATA-Less Promoters: Identification of a New Core Promoter Element XCPE2 and Analysis of Factor Requirements

(2009) Ramakrishnan Anish et al.   PLoS One

Global Analysis of Short RNAs Reveals Widespread Promoter-Proximal Stalling and Arrest of Pol II in Drosophila

(2009) S. Nechaev et al.   SCIENCE

The RNA polymerase II core promoter — the gateway to transcription

(2008) Tamar Juven-Gershon et al.   CURRENT OPINION IN CELL BIOLOGY

TBP, Mot1, and NC2 establish a regulatory circuit that controls DPE-dependent versus TATA-dependent transcription

(2008) J.-Y. Hsu et al.   GENES & DEVELOPMENT

Caudal, a key developmental regulator, is a DPE-specific transcriptional factor

(2008) T. Juven-Gershon et al.   GENES & DEVELOPMENT

MyoD Targets TAF3/TRF3 to Activate Myogenin Transcription

(2008) Maria Divina E. Deato et al.   MOLECULAR CELL

Divergent Transcription from Active Promoters

(2008) Amy C. Seila et al.   SCIENCE

RNA Exosome Depletion Reveals Transcription Upstream of Active Human Promoters

(2008) Pascal Preker et al.   SCIENCE

Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters

(2008) Leighton J. Core et al.   SCIENCE