Linking Stochastic Fluctuations in Chromatin Structure and Gene Expression

Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise

(2013) M. Dadiani et al.   GENOME RESEARCH

Formation and Fate of a Complete 31-Protein RNA Polymerase II Transcription Preinitiation Complex

(2013) Kenji Murakami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamics of protein noise can distinguish between alternate sources of gene-expression variability

(2012) Abhyudai Singh et al.   Molecular Systems Biology

Genome-wide protein–DNA binding dynamics suggest a molecular clutch for transcription factor function

(2012) Colin R. Lickwar et al.   NATURE

The accessible chromatin landscape of the human genome

(2012) Robert E. Thurman et al.   NATURE

Using Gene Expression Noise to Understand Gene Regulation

(2012) B. Munsky et al.   SCIENCE

The lac Repressor Displays Facilitated Diffusion in Living Cells

(2012) P. Hammar et al.   SCIENCE

In VivoRole for the Chromatin-remodeling Enzyme SWI/SNF in the Removal of Promoter Nucleosomes by Disassembly Rather Than Sliding

(2011) Christopher R. Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast

(2011) C. Miller et al.   Molecular Systems Biology

General properties of transcriptional time series in Escherichia coli

(2011) Lok-hang So et al.   NATURE GENETICS

Occlusion of Regulatory Sequences by Promoter Nucleosomes In Vivo

(2011) Changhui Mao et al.   PLoS One

SWI/SNF Has Intrinsic Nucleosome Disassembly Activity that Is Dependent on Adjacent Nucleosomes

(2010) Mekonnen Lemma Dechassa et al.   MOLECULAR CELL

Non-genetic heterogeneity from stochastic partitioning at cell division

(2010) Dann Huh et al.   NATURE GENETICS

Nucleosome positioning and gene regulation: advances through genomics

(2009) Cizhong Jiang et al.   NATURE REVIEWS GENETICS

Nucleosomal Fluctuations Govern the Transcription Dynamics of RNA Polymerase II

(2009) C. Hodges et al.   SCIENCE

Global Analysis of Short RNAs Reveals Widespread Promoter-Proximal Stalling and Arrest of Pol II in Drosophila

(2009) S. Nechaev et al.   SCIENCE

Nucleosome Retention and the Stochastic Nature of Promoter Chromatin Remodeling for Transcription

(2008) Hinrich Boeger et al.   CELL

A quantitative model of transcription factor–activated gene expression

(2008) Harold D Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Single-RNA counting reveals alternative modes of gene expression in yeast

(2008) Daniel Zenklusen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY