Loss of PINK1 leads to metabolic deficits in adult neural stem cells and impedes differentiation of newborn neurons in the mouse hippocampus
出版年份 2017 全文链接
标题
Loss of PINK1 leads to metabolic deficits in adult neural stem cells and impedes differentiation of newborn neurons in the mouse hippocampus
作者
关键词
-
出版物
FASEB JOURNAL
Volume 31, Issue 7, Pages 2839-2853
出版商
FASEB
发表日期
2017-03-22
DOI
10.1096/fj.201600960rr
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis
- (2017) Ruth Beckervordersandforth et al. NEURON
- Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program
- (2016) Mireille Khacho et al. Cell Stem Cell
- Cellular Allometry of Mitochondrial Functionality Establishes the Optimal Cell Size
- (2016) Teemu P. Miettinen et al. DEVELOPMENTAL CELL
- Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC α-synuclein transgenic rat model of Parkinson's disease
- (2016) Zacharias Kohl et al. NEUROBIOLOGY OF DISEASE
- Subtle alterations of excitatory transmission are linked to presynaptic changes in the hippocampus of PINK1-deficient mice
- (2016) Marco Feligioni et al. SYNAPSE
- Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation
- (2016) Xinde Zheng et al. eLife
- The current state of the neurogenic theory of depression and anxiety
- (2015) Bradley R Miller et al. CURRENT OPINION IN NEUROBIOLOGY
- Accumulation of Mitochondrial DNA Mutations Disrupts Cardiac Progenitor Cell Function and Reduces Survival
- (2015) Amabel M. Orogo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Role of Oxidative Stress-Induced Epigenetic Alterations in Amyloid-βProduction in Alzheimer’s Disease
- (2015) Li Zuo et al. Oxidative Medicine and Cellular Longevity
- Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease
- (2015) Brent J. Ryan et al. TRENDS IN BIOCHEMICAL SCIENCES
- Adult neurogenesis: a substrate for experience-dependent change
- (2015) Maya Opendak et al. TRENDS IN COGNITIVE SCIENCES
- An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate
- (2015) Maria Maryanovich et al. Nature Communications
- mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling
- (2015) Riikka H. Hämäläinen et al. Cell Reports
- NRF2 Regulates PINK1 Expression under Oxidative Stress Conditions
- (2015) Hitoshi Murata et al. PLoS One
- Neural stem cells in Parkinson’s disease: a role for neurogenesis defects in onset and progression
- (2014) Jaclyn Nicole Le Grand et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis
- (2014) Julia Marschallinger et al. EXPERIMENTAL GERONTOLOGY
- Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis
- (2014) Heather M. Wilkins et al. HUMAN MOLECULAR GENETICS
- Ca2+-mediated Mitochondrial Reactive Oxygen Species Metabolism Augments Wnt/β-Catenin Pathway Activation to Facilitate Cell Differentiation
- (2014) Tareck Rharass et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondria Modify Exercise-Induced Development of Stem Cell-Derived Neurons in the Adult Brain
- (2014) K. Steib et al. JOURNAL OF NEUROSCIENCE
- PINK1 Loss-of-Function Mutations Affect Mitochondrial Complex I Activity via NdufA10 Ubiquinone Uncoupling
- (2014) V. A. Morais et al. SCIENCE
- Bioenergetic Shifts during Transitions between Stem Cell States (2013 Grover Conference Series)
- (2014) Lianghui Zhang et al. Pulmonary Circulation
- Mitochondrial fission-fusion as an emerging key regulator of cell proliferation and differentiation
- (2013) Kasturi Mitra BIOESSAYS
- Mitochondrial Regulation in Pluripotent Stem Cells
- (2013) Xiuling Xu et al. Cell Metabolism
- Mitochondrial Diseases of the Brain
- (2013) Rajnish K. Chaturvedi et al. FREE RADICAL BIOLOGY AND MEDICINE
- Impaired basal and running-induced hippocampal neurogenesis coincides with reduced Akt signaling in adult R6/1 HD mice
- (2013) Mark I. Ransome et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Metabolism in physiological cell proliferation and differentiation
- (2013) Michalis Agathocleous et al. TRENDS IN CELL BIOLOGY
- Enhanced dendritogenesis and axogenesis in hippocampal neuroblasts of LRRK2 knockout mice
- (2012) Marie Paus et al. BRAIN RESEARCH
- Adult neurogenesis in Parkinson’s disease
- (2012) Franz Marxreiter et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease
- (2012) Michael H. Yan et al. FREE RADICAL BIOLOGY AND MEDICINE
- Age-dependent effects of hippocampal neurogenesis suppression on spatial learning
- (2012) Alonso Martinez-Canabal et al. HIPPOCAMPUS
- Phosphatase and Tensin Homolog (PTEN)-induced Putative Kinase 1 (PINK1)-dependent Ubiquitination of Endogenous Parkin Attenuates Mitophagy
- (2012) Aleksandar Rakovic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Retinoic acid-induced differentiation increases the rate of oxygen consumption and enhances the spare respiratory capacity of mitochondria in SH-SY5Y cells
- (2012) Zhiyin Xun et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Shared and Cell Type-Specific Mitochondrial Defects and Metabolic Adaptations in Primary Cells from PINK1-Deficient Mice
- (2012) Ravi S. Akundi et al. Neurodegenerative Diseases
- Adult Neurogenesis Transiently Generates Oxidative Stress
- (2012) Noah M. Walton et al. PLoS One
- Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson's Disease
- (2012) O. Cooper et al. Science Translational Medicine
- Involvement of PGC-1α in the formation and maintenance of neuronal dendritic spines
- (2012) Aiwu Cheng et al. Nature Communications
- Assessing mitochondrial dysfunction in cells
- (2011) Martin D. Brand et al. BIOCHEMICAL JOURNAL
- Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming
- (2011) Clifford D.L. Folmes et al. Cell Metabolism
- Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner
- (2011) Janel E. Le Belle et al. Cell Stem Cell
- The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons
- (2011) Wendou Yu et al. HUMAN MOLECULAR GENETICS
- Mitochondrial Parkin Recruitment Is Impaired in Neurons Derived from Mutant PINK1 Induced Pluripotent Stem Cells
- (2011) P. Seibler et al. JOURNAL OF NEUROSCIENCE
- Adult hippocampal neurogenesis buffers stress responses and depressive behaviour
- (2011) Jason S. Snyder et al. NATURE
- Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions
- (2011) Guo-li Ming et al. NEURON
- Increased Mitochondrial Calcium Sensitivity and Abnormal Expression of Innate Immunity Genes Precede Dopaminergic Defects in Pink1-Deficient Mice
- (2011) Ravi S. Akundi et al. PLoS One
- Mutant α-synuclein and aging reduce neurogenesis in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson’s disease
- (2010) Jun Peng et al. AGING CELL
- Neurogenesis in mouse models of Alzheimer's disease
- (2010) Tsu Tshen Chuang BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Evaluation of 5-ethynyl-2′-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system
- (2010) Chenbo Zeng et al. BRAIN RESEARCH
- Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
- (2010) Matthew E. Gegg et al. HUMAN MOLECULAR GENETICS
- Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice
- (2010) B. Winner et al. NEUROBIOLOGY OF DISEASE
- Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease
- (2010) Jessica M. Simpson et al. NEUROBIOLOGY OF DISEASE
- The Senescence-Related Mitochondrial/Oxidative Stress Pathway is Repressed in Human Induced Pluripotent Stem Cells
- (2010) Alessandro Prigione et al. STEM CELLS
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- Caspase-2 activation in neural stem cells undergoing oxidative stress-induced apoptosis
- (2008) Christoffer Tamm et al. APOPTOSIS
- Mechanisms and Functional Implications of Adult Neurogenesis
- (2008) Chunmei Zhao et al. CELL
- -Synuclein Alters Notch-1 Expression and Neurogenesis in Mouse Embryonic Stem Cells and in the Hippocampus of Transgenic Mice
- (2008) L. Crews et al. JOURNAL OF NEUROSCIENCE
- Impaired Adult Neurogenesis in the Dentate Gyrus of a Triple Transgenic Mouse Model of Alzheimer's Disease
- (2008) José J. Rodríguez et al. PLoS One
- The PINK1/Parkin pathway regulates mitochondrial morphology
- (2008) A. C. Poole et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A chemical method for fast and sensitive detection of DNA synthesis in vivo
- (2008) A. Salic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutant α-synuclein exacerbates age-related decrease of neurogenesis
- (2007) Beate Winner et al. NEUROBIOLOGY OF AGING
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More