Selective activation of epidermal growth factor receptor in renal proximal tubule induces tubulointerstitial fibrosis

Tumor suppressor ataxia telangiectasia mutated functions downstream of TGF-β1 in orchestrating profibrotic responses

(2015) Jessica M. Overstreet et al.   FASEB JOURNAL

Loss of tumour suppressor PTEN expression in renal injury initiates SMAD3- and p53-dependent fibrotic responses

(2015) Rohan Samarakoon et al.   JOURNAL OF PATHOLOGY

Exploring the origin and limitations of kidney regeneration

(2015) Tomomi Endo et al.   JOURNAL OF PATHOLOGY

Paracrine Wnt1 Drives Interstitial Fibrosis without Inflammation by Tubulointerstitial Cross-Talk

(2015) O. H. Maarouf et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

(2015) M Teresa Grande et al.   NATURE MEDICINE

Fibrosis — A Common Pathway to Organ Injury and Failure

(2015) Don C. Rockey et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Role of M2 Macrophages in the Progression of Chronic Kidney Disease following Acute Kidney Injury

(2015) Myung-Gyu Kim et al.   PLoS One

Epidermal Growth Factor Receptor Inhibition Slows Progression of Diabetic Nephropathy in Association With a Decrease in Endoplasmic Reticulum Stress and an Increase in Autophagy

(2014) Ming-Zhi Zhang et al.   DIABETES

Inflammatory processes in renal fibrosis

(2014) Xiao-Ming Meng et al.   Nature Reviews Nephrology

Targeting CTGF, EGF and PDGF pathways to prevent progression of kidney disease

(2014) Helena M. Kok et al.   Nature Reviews Nephrology

Macrophage heterogeneity, phenotypes, and roles in renal fibrosis

(2014) Qi Cao et al.   Kidney International Supplements

TWEAK transactivation of the epidermal growth factor receptor mediates renal inflammation

(2013) Sandra Rayego-Mateos et al.   JOURNAL OF PATHOLOGY

Low nitric oxide bioavailability upregulates renal heparin binding EGF-like growth factor expression

(2013) Tomoki Miyazawa et al.   KIDNEY INTERNATIONAL

Chronic kidney disease: global dimension and perspectives

(2013) Vivekanand Jha et al.   LANCET

Molecular mechanisms underlying RB protein function

(2013) Frederick A. Dick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Therapy for Fibrotic Diseases: Nearing the Starting Line

(2013) S. L. Friedman et al.   Science Translational Medicine

Connective tissue growth factor is a new ligand of epidermal growth factor receptor

(2013) Sandra Rayego-Mateos et al.   Journal of Molecular Cell Biology

CSF-1 signaling mediates recovery from acute kidney injury

(2012) Ming-Zhi Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic or Pharmacologic Blockade of EGFR Inhibits Renal Fibrosis

(2012) N. Liu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sonic Hedgehog Signaling Mediates Epithelial-Mesenchymal Communication and Promotes Renal Fibrosis

(2012) H. Ding et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis

(2012) Ivica Grgic et al.   KIDNEY INTERNATIONAL

Fibroblasts and myofibroblasts in renal fibrosis

(2011) Soma Meran et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

EGFR Signaling Promotes TGF -Dependent Renal Fibrosis

(2011) J. Chen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The contribution of chronic kidney disease to the global burden of major noncommunicable diseases

(2011) William G. Couser et al.   KIDNEY INTERNATIONAL

Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

(2011) Guillaume Bollée et al.   NATURE MEDICINE

Cellular and molecular mechanisms of renal fibrosis

(2011) Youhua Liu   Nature Reviews Nephrology

Cellular Maintenance and Repair of the Kidney

(2010) Jian-Kan Guo et al.   Annual Review of Physiology

Heparin binding epidermal growth factor in renal ischaemia/reperfusion injury

(2010) Gemma M Mulder et al.   JOURNAL OF PATHOLOGY

Pivotal role of CD4+ T cells in renal fibrosis following ureteric obstruction

(2010) Thomas T. Tapmeier et al.   KIDNEY INTERNATIONAL

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of the EGF family of ligands and receptors in renal development, physiology and pathophysiology

(2008) Fenghua Zeng et al.   EXPERIMENTAL CELL RESEARCH