Tumor suppressor ataxia telangiectasia mutated functions downstream of TGF-β1 in orchestrating profibrotic responses

Redox control of p53 in the transcriptional regulation of TGF-β1 target genes through SMAD cooperativity

(2014) Jessica M. Overstreet et al.   CELLULAR SIGNALLING

Targeted Deletion of p53 in the Proximal Tubule Prevents Ischemic Renal Injury

(2014) Y. Ying et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species

(2013) Rohan Samarakoon et al.   CELLULAR SIGNALLING

Senescence-associated secretory phenotype in a mouse model of bleomycin-induced lung injury

(2013) Kazutetsu Aoshiba et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

TGF-β signaling in tissue fibrosis: Redox controls, target genes and therapeutic opportunities

(2012) Rohan Samarakoon et al.   CELLULAR SIGNALLING

Matrix-dependent perturbation of TGFβ signaling and disease

(2012) Jefferson J. Doyle et al.   FEBS LETTERS

Discovery and Validation of a Molecular Signature for the Noninvasive Diagnosis of Human Renal Allograft Fibrosis

(2012) Dany Anglicheau et al.   TRANSPLANTATION

TGF-β1 → SMAD/p53/USF2 → PAI-1 transcriptional axis in ureteral obstruction-induced renal fibrosis

(2011) Rohan Samarakoon et al.   CELL AND TISSUE RESEARCH

The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91phox mediate hepatic fibrosis in mice

(2011) Yong-Han Paik et al.   HEPATOLOGY

Cellular and molecular mechanisms of renal fibrosis

(2011) Youhua Liu   Nature Reviews Nephrology

Urinary transforming growth factor-β1 in children with obstructive uropathy

(2011) JAKUB ZIEG et al.   NEPHROLOGY

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy

(2009) Robert L. Chevalier et al.   KIDNEY INTERNATIONAL

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

Transforming Growth Factor-β Requires Its Target Plasminogen Activator Inhibitor-1 for Cytostatic Activity

(2008) Roderik M. Kortlever et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

(2008) Martin F. Lavin   NATURE REVIEWS MOLECULAR CELL BIOLOGY