标题
Inflammasomes, the eye and anti-inflammasome therapy
作者
关键词
-
出版物
EYE
Volume 32, Issue 3, Pages 491-505
出版商
Springer Nature
发表日期
2017-11-24
DOI
10.1038/eye.2017.241
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
- (2016) Yuan He et al. NATURE
- Retinal Ganglion Cell Loss is Delayed Following Optic Nerve Crush in NLRP3 Knockout Mice
- (2016) Zhen Puyang et al. Scientific Reports
- Mitochondrial damage contributes toPseudomonas aeruginosaactivation of the inflammasome and is downregulated by autophagy
- (2015) Majid Sakhi Jabir et al. Autophagy
- Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome
- (2015) Yiqing Yan et al. CELL
- The NLRP1 inflammasomes
- (2015) Joseph Chavarría-Smith et al. IMMUNOLOGICAL REVIEWS
- β-arrestin1 Is Critical for the Full Activation of NLRP3 and NLRC4 Inflammasomes
- (2015) Kairui Mao et al. JOURNAL OF IMMUNOLOGY
- Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage
- (2015) Carolina Brandstetter et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-κB pathway in acute glaucoma
- (2015) Wei Chi et al. Journal of Neuroinflammation
- NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component
- (2015) Hexin Shi et al. NATURE IMMUNOLOGY
- Protective and detrimental roles of inflammasomes in disease
- (2015) Pedro H. V. Saavedra et al. Seminars in Immunopathology
- Mechanisms and Functions of Inflammasomes
- (2014) Mohamed Lamkanfi et al. CELL
- Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye
- (2014) Qinxiang Zheng et al. EXPERIMENTAL EYE RESEARCH
- G Protein Signaling Modulator-3 Inhibits the Inflammasome Activity of NLRP3
- (2014) Patrick M. Giguère et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IL-18 is not therapeutic for neovascular age-related macular degeneration
- (2014) Yoshio Hirano et al. NATURE MEDICINE
- DICER1/AluRNA dysmetabolism induces Caspase-8–mediated cell death in age-related macular degeneration
- (2014) Younghee Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1 production in acute glaucoma
- (2014) W. Chi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- C3a modulates IL-1 secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation
- (2013) E. Asgari et al. BLOOD
- Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation
- (2013) Y-H Wu et al. CELL DEATH AND DIFFERENTIATION
- Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock
- (2013) Kairui Mao et al. CELL RESEARCH
- (De-) Oiling Inflammasomes
- (2013) Robyn Marty-Roix et al. IMMUNITY
- Dimethyl sulfoxide inhibits NLRP3 inflammasome activation
- (2013) Huijeong Ahn et al. IMMUNOBIOLOGY
- NLRP1 Is an Inflammasome Sensor for Toxoplasma gondii
- (2013) Sarah E. Ewald et al. INFECTION AND IMMUNITY
- Novel NLRP3/cryopyrin mutations and pro-inflammatory cytokine profiles in Behçet’s syndrome patients
- (2013) Şahru Yüksel et al. INTERNATIONAL IMMUNOLOGY
- Host Defense at the Ocular Surface
- (2013) Eric Pearlman et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- 3,4-Methylenedioxy-β-nitrostyrene Inhibits NLRP3 Inflammasome Activation by Blocking Assembly of the Inflammasome
- (2013) Yuan He et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Novel Pharmacologic Inhibitor of the NLRP3 Inflammasome Limits Myocardial Injury After Ischemia–Reperfusion in the Mouse
- (2013) Carlo Marchetti et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury
- (2013) Nicolas Deroide et al. JOURNAL OF CLINICAL INVESTIGATION
- Synthetic Oligodeoxynucleotides Containing Suppressive TTAGGG Motifs Inhibit AIM2 Inflammasome Activation
- (2013) J. J. Kaminski et al. JOURNAL OF IMMUNOLOGY
- Arsenic Trioxide and Other Arsenical Compounds Inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 Inflammasomes
- (2013) N. K. Maier et al. JOURNAL OF IMMUNOLOGY
- The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis
- (2013) Huan Yang et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophages
- (2013) Marietta M. Budai et al. MOLECULAR IMMUNOLOGY
- Host Response and Bacterial Virulence Factor Expression in Pseudomonas aeruginosa and Streptococcus pneumoniae Corneal Ulcers
- (2013) Rajapandian SivaGanesa Karthikeyan et al. PLoS One
- Staphylococcus aureus Activates the NLRP3 Inflammasome in Human and Rat Conjunctival Goblet Cells
- (2013) Victoria E. McGilligan et al. PLoS One
- Polyenylpyrrole Derivatives Inhibit NLRP3 Inflammasome Activation and Inflammatory Mediator Expression by Reducing Reactive Oxygen Species Production and Mitogen-Activated Protein Kinase Activation
- (2013) Kuo-Feng Hua et al. PLoS One
- The inflammasome and danger associated molecular patterns (DAMPs) are implicated in cytokine and chemokine responses following stressor exposure
- (2012) Thomas Maslanik et al. BRAIN BEHAVIOR AND IMMUNITY
- DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88
- (2012) Valeria Tarallo et al. CELL
- A new eye on NLR proteins: focused on clarity or diffused by complexity?
- (2012) Vera Bonardi et al. CURRENT OPINION IN IMMUNOLOGY
- Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes
- (2012) Hye-Mi Lee et al. DIABETES
- TXNIP Links Innate Host Defense Mechanisms to Oxidative Stress and Inflammation in Retinal Muller Glia under Chronic Hyperglycemia: Implications for Diabetic Retinopathy
- (2012) Takhellambam S. Devi et al. Experimental Diabetes Research
- Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells—Implications for age-related macular degeneration (AMD)
- (2012) Anu Kauppinen et al. IMMUNOLOGY LETTERS
- Autolytic Proteolysis within the Function to Find Domain (FIIND) Is Required for NLRP1 Inflammasome Activity
- (2012) Joshua N. Finger et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NLRP3 Inflammasome Activity Is Negatively Controlled by miR-223
- (2012) F. Bauernfeind et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: miR-223 and EBV miR-BART15 Regulate the NLRP3 Inflammasome and IL-1 Production
- (2012) M. Haneklaus et al. JOURNAL OF IMMUNOLOGY
- Evidence For Multiple Cell Death Pathways during Development of Experimental Cytomegalovirus Retinitis in Mice with Retrovirus-Induced Immunosuppression: Apoptosis, Necroptosis, and Pyroptosis
- (2012) H. Chien et al. JOURNAL OF VIROLOGY
- NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components
- (2012) Sarah L Doyle et al. NATURE MEDICINE
- HMGB1: A multifunctional alarmin driving autoimmune and inflammatory disease
- (2012) Helena Erlandsson Harris et al. Nature Reviews Rheumatology
- Regulation of Retinal Proteome by Topical Antiglaucomatous Eye Drops in an Inherited Glaucoma Rat Model
- (2012) Maurice Schallenberg et al. PLoS One
- NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury
- (2012) Catherine Diane Savage et al. Frontiers in Immunology
- HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection
- (2011) Ulf Andersson et al. Annual Review of Immunology
- The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases
- (2011) Beckley K. Davis et al. Annual Review of Immunology
- The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond
- (2011) Cristina Conforti-Andreoni et al. Cellular & Molecular Immunology
- Understanding the mechanism of IL-1β secretion
- (2011) Gloria Lopez-Castejon et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Toll-like receptor 3, RIG-I-like receptors and the NLRP3 inflammasome: Key modulators of innate immune responses to double-stranded RNA viruses
- (2011) Man Yu et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
- (2011) Greta Guarda et al. IMMUNITY
- The inflammasome: an integrated view
- (2011) Olaf Gross et al. IMMUNOLOGICAL REVIEWS
- Critical Roles of ASC Inflammasomes in Caspase-1 Activation and Host Innate Resistance to Streptococcus pneumoniae Infection
- (2011) R. Fang et al. JOURNAL OF IMMUNOLOGY
- Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
- (2011) Eric M. Kofoed et al. NATURE
- The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization
- (2011) Sirish K Ippagunta et al. NATURE IMMUNOLOGY
- Caspase-1 Dependent IL-1β Secretion Is Critical for Host Defense in a Mouse Model of Chlamydia pneumoniae Lung Infection
- (2011) Kenichi Shimada et al. PLoS One
- Why not treat human cancer with interleukin-1 blockade?
- (2010) Charles A. Dinarello CANCER AND METASTASIS REVIEWS
- Pattern Recognition Receptors and Inflammation
- (2010) Osamu Takeuchi et al. CELL
- Pseudomonas aeruginosa pilin activates the inflammasome
- (2010) Cecilia S. Lindestam Arlehamn et al. CELLULAR MICROBIOLOGY
- A 3′UTR SNP in NLRP3 Gene is Associated With Susceptibility to HIV-1 Infection
- (2010) Alessandra Pontillo et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome
- (2010) Christine Juliana et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tripartite-Motif Protein 30 Negatively Regulates NLRP3 Inflammasome Activation by Modulating Reactive Oxygen Species Production
- (2010) Y. Hu et al. JOURNAL OF IMMUNOLOGY
- The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
- (2010) Vijay A K Rathinam et al. NATURE IMMUNOLOGY
- The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
- (2010) Teresa Fernandes-Alnemri et al. NATURE IMMUNOLOGY
- Influenza virus activates inflammasomes via its intracellular M2 ion channel
- (2010) Takeshi Ichinohe et al. NATURE IMMUNOLOGY
- Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
- (2010) Kiichi Nakahira et al. NATURE IMMUNOLOGY
- Immunological and Inflammatory Functions of the Interleukin-1 Family
- (2009) Charles A. Dinarello Annual Review of Immunology
- The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA
- (2009) Irving C. Allen et al. IMMUNITY
- Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
- (2009) Mohamed Lamkanfi et al. JOURNAL OF CELL BIOLOGY
- Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions
- (2009) Lorena Perrone et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
- (2009) Olaf Gross et al. NATURE
- Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
- (2009) S. S. Iyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mycobacterium tuberculosis Prevents Inflammasome Activation
- (2008) Sharon S. Master et al. Cell Host & Microbe
- Human Alu RNA Is a Modular Transacting Repressor of mRNA Transcription during Heat Shock
- (2008) Peter D. Mariner et al. MOLECULAR CELL
- Pseudomonas aeruginosa activates caspase 1 through Ipaf
- (2008) E. A. Miao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
- (2008) C. Dostert et al. SCIENCE
- Retinal Precursors and the Development of Geographic Atrophy in Age-Related Macular Degeneration
- (2007) Michael L. Klein et al. OPHTHALMOLOGY
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