标题
Nutrient sensing pathways as therapeutic targets for healthy ageing
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 21, Issue 4, Pages 371-380
出版商
Informa UK Limited
发表日期
2017-02-16
DOI
10.1080/14728222.2017.1294684
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- The role of sirtuins in aging and age-related diseases
- (2016) Mateusz Wątroba et al. Advances in Medical Sciences
- Dietary Protein, Metabolism, and Aging
- (2016) George A. Soultoukis et al. Annual Review of Biochemistry
- Ageing with elegans: a research proposal to map healthspan pathways
- (2016) Walter Luyten et al. BIOGERONTOLOGY
- Repurposing FDA-approved drugs for anti-aging therapies
- (2016) Terry W. Snell et al. BIOGERONTOLOGY
- Growing older with health and vitality: a nexus of physical activity, exercise and nutrition
- (2016) Oliver C. Witard et al. BIOGERONTOLOGY
- The Somatotropic Axis in Human Aging: Framework for the Current State of Knowledge and Future Research
- (2016) Sofiya Milman et al. Cell Metabolism
- Metformin as a Tool to Target Aging
- (2016) Nir Barzilai et al. Cell Metabolism
- The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging
- (2016) Brian K. Kennedy et al. Cell Metabolism
- Metformin and the gastrointestinal tract
- (2016) Laura J. McCreight et al. DIABETOLOGIA
- Mediterranean nutraceutical foods: Strategy to improve vascular ageing
- (2016) Giulia Accardi et al. MECHANISMS OF AGEING AND DEVELOPMENT
- The Human Intestinal Microbiome in Health and Disease
- (2016) Susan V. Lynch et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nutrigerontology: a key for achieving successful ageing and longevity
- (2016) Anna Aiello et al. Immunity & Ageing
- Validation of anti-aging drugs by treating age-related diseases
- (2016) Mikhail V. Blagosklonny Aging-US
- Interventions to Slow Aging in Humans: Are We Ready?
- (2015) Valter D. Longo et al. AGING CELL
- The Roles of mTOR Complexes in Lipid Metabolism
- (2015) Alexandre Caron et al. Annual Review of Nutrition
- Akkermansia muciniphila Adheres to Enterocytes and Strengthens the Integrity of the Epithelial Cell Layer
- (2015) Justus Reunanen et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- The somatotropic axis may not modulate ageing and longevity in humans
- (2015) Éric Le Bourg BIOGERONTOLOGY
- GH Receptor Deficiency in Ecuadorian Adults Is Associated With Obesity and Enhanced Insulin Sensitivity
- (2015) Jaime Guevara-Aguirre et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Rejuvenating immunity: “anti-aging drug today” eight years later
- (2015) Mikhail V. Blagosklonny Oncotarget
- Nutrigerontology: why we need a new scientific discipline to develop diets and guidelines to reduce the risk of aging-related diseases
- (2014) Kris Verburgh AGING CELL
- Effect of Metformin on Metabolic Improvement and Gut Microbiota
- (2014) Heetae Lee et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population
- (2014) Morgan E. Levine et al. Cell Metabolism
- Fasting: Molecular Mechanisms and Clinical Applications
- (2014) Valter D. Longo et al. Cell Metabolism
- Association between Genetic Variations in the Insulin/Insulin-Like Growth Factor (Igf-1) Signaling Pathway and Longevity: A Systematic Review and Meta-Analysis
- (2014) Danilo Bona et al. Current Vascular Pharmacology
- The Challenges in Moving from Ageing to Successful Longevity
- (2014) Genovefa Kolovou et al. Current Vascular Pharmacology
- Editorial: Ageing, Longevity, Exceptional Longevity and Related Genetic and Non Genetics Markers: Panel Statement
- (2014) Peter Avery et al. Current Vascular Pharmacology
- Mediterranean Diet and Healthy Ageing: A Sicilian Perspective
- (2014) Sonya Vasto et al. GERONTOLOGY
- Healthy aging diets other than the Mediterranean: A focus on the Okinawan diet
- (2014) Donald Craig Willcox et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Medical research: Treat ageing
- (2014) Luigi Fontana et al. NATURE
- Protein and amino acid restriction, aging and disease: from yeast to humans
- (2014) Hamed Mirzaei et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Small molecule SIRT1 activators for the treatment of aging and age-related diseases
- (2014) Basil P. Hubbard et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Metformin promotes autophagy and apoptosis in esophageal squamous cell carcinoma by downregulating Stat3 signaling
- (2014) Y Feng et al. Cell Death & Disease
- Serine- and Threonine/Valine-Dependent Activation of PDK and Tor Orthologs Converge on Sch9 to Promote Aging
- (2014) Mario G. Mirisola et al. PLoS Genetics
- Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-κB activation
- (2013) Olga Moiseeva et al. AGING CELL
- Inhibition of mTOR Signaling by Quercetin in Cancer Treatment and Prevention
- (2013) Ansgar Bruning Anti-Cancer Agents in Medicinal Chemistry
- Deregulation of PI3K/Akt/mTOR Signaling Pathways by Isoflavones and its Implication in Cancer Treatment
- (2013) Aamir Ahmad et al. Anti-Cancer Agents in Medicinal Chemistry
- Intestinal microbiota, diet and health
- (2013) Susan E. Power et al. BRITISH JOURNAL OF NUTRITION
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- An increase in theAkkermansiaspp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice
- (2013) Na-Ri Shin et al. GUT
- The Role of SIRT6 Protein in Aging and Reprogramming of Human Induced Pluripotent Stem Cells
- (2013) Amit Sharma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
- (2013) Tamara Tchkonia et al. JOURNAL OF CLINICAL INVESTIGATION
- mTOR is a key modulator of ageing and age-related disease
- (2013) Simon C. Johnson et al. NATURE
- Fruit consumption and risk of type 2 diabetes: results from three prospective longitudinal cohort studies
- (2013) I. Muraki et al. BMJ-British Medical Journal
- Dietary flavonoid intakes and risk of type 2 diabetes in US men and women
- (2012) Nicole M Wedick et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Sirtuin activators and inhibitors
- (2012) José M. Villalba et al. BIOFACTORS
- Rationale and methods of discovering hormetins as drugs for healthy ageing
- (2012) Suresh I S Rattan Expert Opinion on Drug Discovery
- NF-κB: where did it come from and why?
- (2012) Thomas D. Gilmore et al. IMMUNOLOGICAL REVIEWS
- Effects of Dietary Composition on Energy Expenditure During Weight-Loss Maintenance
- (2012) Cara B. Ebbeling et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- From Sirtuin Biology to Human Diseases: An Update
- (2012) Carlos Sebastián et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human conditions of insulin-like growth factor-I (IGF-I) deficiency
- (2012) Juan E Puche et al. Journal of Translational Medicine
- Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy
- (2012) W-Y Shi et al. Cell Death & Disease
- Centenarians and diet: what they eat in the Western part of Sicily
- (2012) Sonya Vasto et al. Immunity & Ageing
- Extending healthy ageing: nutrient sensitive pathway and centenarian population
- (2012) Sergio Davinelli et al. Immunity & Ageing
- Hallmarks of human “immunosenescence”: adaptation or dysregulation?
- (2012) Graham Pawelec Immunity & Ageing
- Amino Acid Signaling in TOR Activation
- (2011) Joungmok Kim et al. Annual Review of Biochemistry
- Small-Molecule Allosteric Activators of Sirtuins
- (2011) David A. Sinclair et al. Annual Review of Pharmacology and Toxicology
- Signalling by insulin and IGF receptors: supporting acts and new players
- (2011) Kenneth Siddle JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Caloric restriction
- (2011) John R. Speakman et al. MOLECULAR ASPECTS OF MEDICINE
- Modulation of Nrf2/ARE Pathway by Food Polyphenols: A Nutritional Neuroprotective Strategy for Cognitive and Neurodegenerative Disorders
- (2011) Giovanni Scapagnini et al. MOLECULAR NEUROBIOLOGY
- Metformin inhibits melanoma development through autophagy and apoptosis mechanisms
- (2011) T Tomic et al. Cell Death & Disease
- Age-Related Inflammation: the Contribution of Different Organs, Tissues and Systems. How to Face it for Therapeutic Approaches
- (2010) E. Cevenini et al. CURRENT PHARMACEUTICAL DESIGN
- Low Grade Inflammation as a Common Pathogenetic Denominator in Age-Related Diseases: Novel Drug Targets for Anti-Ageing Strategies and Successful Ageing Achievement
- (2010) G. Candore et al. CURRENT PHARMACEUTICAL DESIGN
- Chronic Rapamycin Treatment Causes Glucose Intolerance and Hyperlipidemia by Upregulating Hepatic Gluconeogenesis and Impairing Lipid Deposition in Adipose Tissue
- (2010) V. P. Houde et al. DIABETES
- The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes
- (2010) D. J. A. Jenkins et al. DIABETOLOGIA
- SIRT2 regulates NF- B-dependent gene expression through deacetylation of p65 Lys310
- (2010) K. M. Rothgiesser et al. JOURNAL OF CELL SCIENCE
- Dietary Anthocyanin-Rich Bilberry Extract Ameliorates Hyperglycemia and Insulin Sensitivity via Activation of AMP-Activated Protein Kinase in Diabetic Mice
- (2010) Masahito Takikawa et al. JOURNAL OF NUTRITION
- The Role of Adipose Tissue and Adipokines in Obesity-Related Inflammatory Diseases
- (2010) Carmela Rita Balistreri et al. MEDIATORS OF INFLAMMATION
- Structure of the Human mTOR Complex I and Its Implications for Rapamycin Inhibition
- (2010) Calvin K. Yip et al. MOLECULAR CELL
- Termination of autophagy and reformation of lysosomes regulated by mTOR
- (2010) Li Yu et al. NATURE
- Composition, variability, and temporal stability of the intestinal microbiota of the elderly
- (2010) M. J. Claesson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Extending Healthy Life Span--From Yeast to Humans
- (2010) L. Fontana et al. SCIENCE
- Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila
- (2009) Richard C. Grandison et al. NATURE
- The new biology of ageing
- (2009) L. Partridge PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans
- (2008) Luigi Fontana et al. AGING CELL
- Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice
- (2008) P. D. Cani et al. DIABETES
- AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
- (2008) Dana M. Gwinn et al. MOLECULAR CELL
- Functionally significant insulin-like growth factor I receptor mutations in centenarians
- (2008) Y. Suh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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