An appraisal of the enzyme stability-activity trade-off

Engineering ancestral protein hyperstability

(2016) M. L. Romero-Romero et al.   BIOCHEMICAL JOURNAL

Characterization of a cold-active esterase from Serratia sp. and improvement of thermostability by directed evolution

(2016) Huang Jiang et al.   BMC BIOTECHNOLOGY

The thermostability and specificity of ancient proteins

(2016) Lucas C Wheeler et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Activity–stability relationships revisited in blue oxidases catalyzing electron transfer at extreme temperatures

(2016) Frédéric Roulling et al.   EXTREMOPHILES

On the Potential Origins of the High Stability of Reconstructed Ancestral Proteins

(2016) Devin L. Trudeau et al.   MOLECULAR BIOLOGY AND EVOLUTION

Enhanced activity of an alkaline phytase from Bacillus subtilis 168 in acidic and neutral environments by directed evolution

(2015) Weiwei Chen et al.   BIOCHEMICAL ENGINEERING JOURNAL

Evaluation and directed evolution for thermostability improvement of a GH 13 thermostable α-glucosidase from Thermus thermophilus TC11

(2015) Cheng Zhou et al.   BMC BIOTECHNOLOGY

Rigidity versus flexibility: the dilemma of understanding protein thermal stability

(2015) Andrey Karshikoff et al.   FEBS Journal

Structural features determining thermal adaptation of esterases

(2015) Filip Kovacic et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Characterization of uronate dehydrogenases catalysing the initial step in an oxidative pathway

(2015) André Pick et al.   Microbial Biotechnology

Identification and Structural Analysis of Amino Acid Substitutions that Increase the Stability and Activity of Aspergillus niger Glucose Oxidase

(2015) Julia Marín-Navarro et al.   PLoS One

Directed evolution of Bacillus licheniformis lipase for improvement of thermostability

(2014) Bhawna Madan et al.   BIOCHEMICAL ENGINEERING JOURNAL

Directed Evolution of a Formate Dehydrogenase for Increased Tolerance to Ionic Liquids Reveals a New Site for Increasing the Stability

(2014) Julie L. L. Carter et al.   CHEMBIOCHEM

Thermodynamic System Drift in Protein Evolution

(2014) Kathryn M. Hart et al.   PLOS BIOLOGY

Metagenomic mining of feruloyl esterases from termite enteric flora

(2013) Konanani Rashamuse et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Directed evolution of phloroglucinol synthase PhlD with increased stability for phloroglucinol production

(2013) Guodong Rao et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Unique arylalkylamine N-acetyltransferase-2 polymorphism in salmonids and profound variations in thermal stability and catalytic efficiency conferred by two residues

(2013) D. Cazamea-Catalan et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Hyperstability and Substrate Promiscuity in Laboratory Resurrections of Precambrian β-Lactamases

(2013) Valeria A. Risso et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The universality of enzymatic rate–temperature dependency

(2013) Mikael Elias et al.   TRENDS IN BIOCHEMICAL SCIENCES

Temperature adaptations in psychrophilic, mesophilic and thermophilic chloride-dependent alpha-amylases

(2012) Alexandre Cipolla et al.   BIOCHIMIE

How Do Thermophilic Proteins and Proteomes Withstand High Temperature?

(2011) Lucas Sawle et al.   BIOPHYSICAL JOURNAL

An analysis of temperature adaptation in cold active, mesophilic and thermophilic Bacillus α-amylases

(2011) Atiyeh Mahdavi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Enhancement of Thermal Stabilization of Formaldehyde Dehydrogenase fromPseudomonas putidaby Directed Evolution

(2010) Chie IMAMURA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Adapting to climate change: a perspective from evolutionary physiology

(2010) SL Chown et al.   CLIMATE RESEARCH

Comparative study on dihydrofolate reductases from Shewanella species living in deep-sea and ambient atmospheric-pressure environments

(2010) Chiho Murakami et al.   EXTREMOPHILES

The physiology of climate change: how potentials for acclimatization and genetic adaptation will determine 'winners' and 'losers'

(2010) G. N. Somero   JOURNAL OF EXPERIMENTAL BIOLOGY

Protein stability and enzyme activity at extreme biological temperatures

(2010) Georges Feller   JOURNAL OF PHYSICS-CONDENSED MATTER

Temperature dependence of the flexibility of thermophilic and mesophilic flavoenzymes of the nitroreductase fold

(2010) Eric D. Merkley et al.   PROTEIN ENGINEERING DESIGN & SELECTION

DnaSP v5: a software for comprehensive analysis of DNA polymorphism data

(2009) P. Librado et al.   BIOINFORMATICS

Comparative thermostability of mesophilic and thermophilic alcohol dehydrogenases: Stability-determining roles of proline residues and loop conformations

(2009) Abolfazl Barzegar et al.   ENZYME AND MICROBIAL TECHNOLOGY

Simultaneous improvement of catalytic activity and thermal stability of tyrosine phenol-lyase by directed evolution

(2009) Eugene Rha et al.   FEBS Journal

Cold Adaptation of Zinc Metalloproteases in the Thermolysin Family from Deep Sea and Arctic Sea Ice Bacteria Revealed by Catalytic and Structural Properties and Molecular Dynamics

(2009) Bin-Bin Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative characterisation of thiamin diphosphate-dependent decarboxylases

(2009) Dörte Gocke et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Dynamics and unfolding pathways of a hyperthermophilic and a mesophilic rubredoxin

(2009) Themis Lazaridis et al.   PROTEIN SCIENCE

Enzymatic Analysis of a Thermostabilized Mutant of anEscherichia coliHygromycin B Phosphotransferase

(2008) Akira NAKAMURA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Temperature adaptation of cytosolic malate dehydrogenases of limpets (genus Lottia): differences in stability and function due to minor changes in sequence correlate with biogeographic and vertical distributions

(2008) Y. Dong et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Directed evolution on the cold adapted properties of TAB5 alkaline phosphatase

(2008) D. Koutsioulis et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Combinatorial engineering to enhance thermostability of amylosucrase

(2008) Stéphane Emond et al.   PROTEIN SCIENCE