Deletion of the type-1 interferon receptor in APPSWE/PS1ΔE9 mice preserves cognitive function and alters glial phenotype

Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes

(2016) Cherie T. Ng et al.   CELL

Novel interferonopathies associated with mutations in RIG-I like receptors

(2016) Insa Buers et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Type I/II Interferon Balance in the Regulation of Brain Physiology and Pathology

(2016) Aleksandra Deczkowska et al.   TRENDS IN IMMUNOLOGY

DNA sensors are expressed in astrocytes and microgliain vitroand are upregulated during gliosis in neurodegenerative disease

(2015) Donal J. Cox et al.   GLIA

The contribution of neuroinflammation to amyloid toxicity in Alzheimer's disease

(2015) Myles R. Minter et al.   JOURNAL OF NEUROCHEMISTRY

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Endogenous murine Aβ increases amyloid deposition in APP23 but not in APPPS1 transgenic mice

(2015) Jasmin Mahler et al.   NEUROBIOLOGY OF AGING

Il10 Deficiency Rebalances Innate Immunity to Mitigate Alzheimer-Like Pathology

(2015) Marie-Victoire Guillot-Sestier et al.   NEURON

IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque Burden and Worsening Cognitive Behavior

(2015) Paramita Chakrabarty et al.   NEURON

The role of inflammation and microglial activation in the pathophysiology of psychiatric disorders

(2015) G.Z. Réus et al.   NEUROSCIENCE

Breaking immune tolerance by targeting Foxp3+ regulatory T cells mitigates Alzheimer’s disease pathology

(2015) Kuti Baruch et al.   Nature Communications

Genetic Modulation of Soluble A  Rescues Cognitive and Synaptic Impairment in a Mouse Model of Alzheimer's Disease

(2014) S. W. Fowler et al.   JOURNAL OF NEUROSCIENCE

Aging-induced type I interferon response at the choroid plexus negatively affects brain function

(2014) K. Baruch et al.   SCIENCE

Amyloid-β induces NLRP1-dependent neuronal pyroptosis in models of Alzheimer’s disease

(2014) M-S Tan et al.   Cell Death & Disease

Inconsistencies and Controversies Surrounding the Amyloid Hypothesis of Alzheimer's Disease

(2014) Gary P Morris et al.   Acta Neuropathologica Communications

The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy

(2013) Patrick L. McGeer et al.   ACTA NEUROPATHOLOGICA

Microglia actions in Alzheimer’s disease

(2013) Stefan Prokop et al.   ACTA NEUROPATHOLOGICA

Interferons in the central nervous system: A few instruments play many tunes

(2013) Trevor Owens et al.   GLIA

Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease

(2013) Juliet M. Taylor et al.   NEUROBIOLOGY OF AGING

Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition

(2012) Paramita Chakrabarty et al.   Molecular Neurodegeneration

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease–like pathology and cognitive decline

(2012) Johannes vom Berg et al.   NATURE MEDICINE

IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype

(2012) Takahiro Masuda et al.   Cell Reports

MyD88-adaptor protein acts as a preventive mechanism for memory deficits in a mouse model of Alzheimer's disease

(2011) Jean-Philippe Michaud et al.   Molecular Neurodegeneration

I B kinase   (IKK ) regulates the balance between type I and type II interferon responses

(2011) S.-L. Ng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice

(2011) Kelley Bromley-Brits et al.   Jove-Journal of Visualized Experiments

Increasing Cu bioavailability inhibits A  oligomers and tau phosphorylation

(2009) P. J. Crouch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors

(2009) Antero Salminen et al.   PROGRESS IN NEUROBIOLOGY

Dissection of Hippocampal Dentate Gyrus from Adult Mouse

(2009) Hideo Hagihara et al.   Jove-Journal of Visualized Experiments

Crystallization and preliminary X-ray diffraction analysis of the Fab fragment of WO2, an antibody specific for the Aβ peptides associated with Alzheimer's disease

(2008) Kwok S. Wun et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Amyloid-β oligomers set fire to inflammasomes and induce Alzheimer's pathology

(2008) Antero Salminen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Rapid Restoration of Cognition in Alzheimer's Transgenic Mice with 8-Hydroxy Quinoline Analogs Is Associated with Decreased Interstitial Aβ

(2008) Paul A. Adlard et al.   NEURON