Systematic chemical-genetic and chemical-chemical interaction datasets for prediction of compound synergism

Dark chemical matter as a promising starting point for drug lead discovery

(2015) Anne Mai Wassermann et al.   Nature Chemical Biology

PubChem Substance and Compound databases

(2015) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

Prediction of Synergism from Chemical-Genetic Interactions by Machine Learning

(2015) Jan Wildenhain et al.   Cell Systems

A community computational challenge to predict the activity of pairs of compounds

(2014) Mukesh Bansal et al.   NATURE BIOTECHNOLOGY

The BioGRID interaction database: 2015 update

(2014) Andrew Chatr-aryamontri et al.   NUCLEIC ACIDS RESEARCH

A Yeast Chemical Genetic Screen Identifies Inhibitors of Human Telomerase

(2013) Lai Hong Wong et al.   CHEMISTRY & BIOLOGY

Systems-level antimicrobial drug and drug synergy discovery

(2013) Terry Roemer et al.   Nature Chemical Biology

MolClass: a web portal to interrogate diverse small molecule screen datasets with different computational models

(2012) J. Wildenhain et al.   BIOINFORMATICS

ALDH2 Mediates 5-Nitrofuran Activity in Multiple Species

(2012) Linna Zhou et al.   CHEMISTRY & BIOLOGY

Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole

(2011) M. Spitzer et al.   Molecular Systems Biology

Systematic exploration of synergistic drug pairs

(2011) M. Cokol et al.   Molecular Systems Biology

Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation

(2010) H. Ishizaki et al.   Disease Models & Mechanisms

Functionality Pattern Matching as an Efficient Complementary Structure/Reaction Search Tool: an Open-Source Approach

(2010) Norbert Haider   MOLECULES

DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs

(2010) C. Knox et al.   NUCLEIC ACIDS RESEARCH

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Systems approaches and algorithms for discovery of combinatorial therapies

(2009) Jacob D. Feala et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Defining genetic interaction

(2008) R. Mani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes

(2008) M. E. Hillenmeyer et al.   SCIENCE