Crosstalk Between Muscle and Bone Via the Muscle-Myokine Irisin

Erratum: Corrigendum: Irisin promotes osteoblast proliferation and differentiation via activating the MAP kinase signaling pathways

(2016) Xiaoyong Qiao et al.   Scientific Reports

Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry

(2015) Mark P. Jedrychowski et al.   Cell Metabolism

Irisin is associated with osteoporotic fractures independently of bone mineral density, body composition or daily physical activity

(2015) Andrea Palermo et al.   CLINICAL ENDOCRINOLOGY

Irisin, a unique non-inflammatory myokine in stimulating skeletal muscle metabolism

(2015) Roger A. Vaughan et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

The myokine irisin increases cortical bone mass

(2015) Graziana Colaianni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Irisin – a myth rather than an exercise-inducible myokine

(2015) Elke Albrecht et al.   Scientific Reports

Mechanisms of Aging-Related Impairment of Brown Adipocyte Development and Function

(2014) Antonia Graja et al.   GERONTOLOGY

Circulating irisin is associated with osteoporotic fractures in postmenopausal women with low bone mass but is not affected by either teriparatide or denosumab treatment for 3 months

(2014) A. D. Anastasilakis et al.   OSTEOPOROSIS INTERNATIONAL

Irisin Levels Are Lower in Young Amenorrheic Athletes Compared with Eumenorrheic Athletes and Non-Athletes and Are Associated with Bone Density and Strength Estimates

(2014) Vibha Singhal et al.   PLoS One

Circulating Sclerostin and Irisin Are Related and Interact with Gender to Influence Adiposity in Adults with Prediabetes

(2014) Theerawut Klangjareonchai et al.   International Journal of Endocrinology

Irisin Enhances Osteoblast DifferentiationIn Vitro

(2014) Graziana Colaianni et al.   International Journal of Endocrinology

Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling

(2013) Y. Zhang et al.   DIABETES

Inducible Brown Adipose Tissue, or Beige Fat, Is Anabolic for the Skeleton

(2013) Sima Rahman et al.   ENDOCRINOLOGY

Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1α-Fndc5 pathway in muscle

(2013) Tizhong Shan et al.   FASEB JOURNAL

Bone and Skeletal Muscle: Neighbors With Close Ties

(2013) Douglas J DiGirolamo et al.   JOURNAL OF BONE AND MINERAL RESEARCH

FNDC5/Irisin Is Not Only a Myokine but Also an Adipokine

(2013) Arturo Roca-Rivada et al.   PLoS One

Inhibition of Myostatin Signaling through Notch Activation following Acute Resistance Exercise

(2013) Matthew G. MacKenzie et al.   PLoS One

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Muscles, exercise and obesity: skeletal muscle as a secretory organ

(2012) Bente K. Pedersen et al.   Nature Reviews Endocrinology

Biology Without Walls: The Novel Endocrinology of Bone

(2011) Gerard Karsenty et al.   Annual Review of Physiology

Sclerostin: A gem from the genome leads to bone-building antibodies

(2010) Chris Paszty et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue

(2009) Maria Cristina Zingaretti et al.   FASEB JOURNAL

Sclerostin Mediates Bone Response to Mechanical Unloading Through Antagonizing Wnt/β-Catenin Signaling

(2009) Chuwen Lin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A longitudinal study of the relationship of physical activity to bone mineral accrual from adolescence to young adulthood

(2008) Adam D.G. Baxter-Jones et al.   BONE

Osteocytes, mechanosensing and Wnt signaling

(2008) Lynda F. Bonewald et al.   BONE

Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH