A small molecule targeting protein translation does not rescue spatial learning and memory deficits in the hAPP-J20 mouse model of Alzheimer’s disease

Plaque-Associated Local Toxicity Increases over the Clinical Course of Alzheimer Disease

(2016) Alberto Serrano-Pozo et al.   AMERICAN JOURNAL OF PATHOLOGY

2015 Alzheimer's disease facts and figures

(2015)   Alzheimers & Dementia

Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory

(2015) Anna G Orr et al.   NATURE NEUROSCIENCE

Review: Modulating the unfolded protein response to prevent neurodegeneration and enhance memory

(2015) Mark Halliday et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Mutations in a translation initiation factor identify the target of a memory-enhancing compound

(2015) Y. Sekine et al.   SCIENCE

Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma

(2015) L R Palam et al.   Cell Death & Disease

Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity

(2015) M Halliday et al.   Cell Death & Disease

Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response

(2015) Carmela Sidrauski et al.   eLife

The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly

(2015) Carmela Sidrauski et al.   eLife

Functional roles of CREB as a positive regulator in the formation and enhancement of memory

(2014) Satoshi Kida et al.   BRAIN RESEARCH BULLETIN

Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α

(2014) Gonzalo Viana Di Prisco et al.   NATURE NEUROSCIENCE

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

(2014) Scott J. Webster et al.   Frontiers in Genetics

Blocking the eIF2  Kinase (PKR) Enhances Positive and Negative Forms of Cortex-Dependent Taste Memory

(2013) E. Stern et al.   JOURNAL OF NEUROSCIENCE

Pharmacological brake-release of mRNA translation enhances cognitive memory

(2013) Carmela Sidrauski et al.   eLife

Synaptic changes in Alzheimer’s disease and its models

(2012) J. Pozueta et al.   NEUROSCIENCE

Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model

(2012) P. E. Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

(2010) Moustapha Cissé et al.   NATURE

Group 1 mGluR-Dependent Synaptic Long-Term Depression: Mechanisms and Implications for Circuitry and Disease

(2010) Christian Lüscher et al.   NEURON

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease

(2008) Rene O Sanchez-Mejia et al.   NATURE NEUROSCIENCE