Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease

SLC30A10 Is a Cell Surface-Localized Manganese Efflux Transporter, and Parkinsonism-Causing Mutations Block Its Intracellular Trafficking and Efflux Activity

(2014) D. Leyva-Illades et al.   JOURNAL OF NEUROSCIENCE

The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans

(2013) Julia Bornhorst et al.   Metallomics

Advances in the genetics of Parkinson disease

(2013) Joanne Trinh et al.   Nature Reviews Neurology

Mutations in SLC30A10 Cause Parkinsonism and Dystonia with Hypermanganesemia, Polycythemia, and Chronic Liver Disease

(2012) Marialuisa Quadri et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Parkinson's disease, insulin resistance and novel agents of neuroprotection

(2012) Iciar Aviles-Olmos et al.   BRAIN

DJ-1 protein protects dopaminergic neurons against 6-OHDA/MG-132-induced neurotoxicity in rats

(2012) Shuang-Yong Sun et al.   BRAIN RESEARCH BULLETIN

Organotellurium and organoselenium compounds attenuate Mn-induced toxicity in Caenorhabditis elegans by preventing oxidative stress

(2012) Daiana Silva Avila et al.   FREE RADICAL BIOLOGY AND MEDICINE

Human DJ-1 and its homologs are novel glyoxalases

(2012) Ju-young Lee et al.   HUMAN MOLECULAR GENETICS

Diabetes and risk of Parkinson's disease

(2012) Emanuele Cereda et al.   MOVEMENT DISORDERS

Increased risk of parkinsonism associated with welding exposure

(2012) Brad A. Racette et al.   NEUROTOXICOLOGY

Forward Genetic Analysis to Identify Determinants of Dopamine Signaling in Caenorhabditis elegans Using Swimming-Induced Paralysis

(2012) J. Andrew Hardaway et al.   G3-Genes Genomes Genetics

Cell-Nonautonomous Signaling of FOXO/DAF-16 to the Stem Cells of Caenorhabditis elegans

(2012) Wenjing Qi et al.   PLoS Genetics

Genes That Act Downstream of Sensory Neurons to Influence Longevity, Dauer Formation, and Pathogen Responses in Caenorhabditis elegans

(2012) Marta M. Gaglia et al.   PLoS Genetics

Diapause Formation and Downregulation of Insulin-Like Signaling via DAF-16/FOXO Delays Axonal Degeneration and Neuronal Loss

(2012) Andrea Calixto et al.   PLoS Genetics

15-Deoxy-Δ12,14-prostaglandin J2 modulates manganese-induced activation of the NF-κB, Nrf2, and PI3K pathways in astrocytes

(2011) Eunsook Lee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protection Against Dopaminergic Neurodegeneration in Parkinson’s Disease–Model Animals by a Modulator of the Oxidized Form of DJ-1, a Wild-type of Familial Parkinson’s Disease–Linked PARK7

(2011) Masatoshi Inden et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Role of manganese in neurodegenerative diseases

(2011) Aaron B. Bowman et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

DJ-1 mediates paraquat-induced dopaminergic neuronal cell death

(2011) Hyun Joo Kwon et al.   TOXICOLOGY LETTERS

Cellular mechanisms of posterior neural tube morphogenesis in the zebrafish

(2010) Michael J. Harrington et al.   DEVELOPMENTAL DYNAMICS

Environmental Exposure, Obesity, and Parkinson’s Disease: Lessons from Fat and Old Worms

(2010) Layla Aitlhadj et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Keap1-Nrf2 activation in the presence and absence of DJ-1

(2010) Li Gan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Effects of sod gene overexpression and deletion mutation on the expression profiles of reporter genes of major detoxification pathways in Caenorhabditis elegans

(2010) Patricia Back et al.   EXPERIMENTAL GERONTOLOGY

DJ-1, an oncogene and causative gene for familial Parkinson's disease, is essential for SV40 transformation in mouse fibroblasts through up-regulation of c-Myc

(2010) Yun Chul Kim et al.   FEBS LETTERS

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics

(2010) I. Irrcher et al.   HUMAN MOLECULAR GENETICS

Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update

(2010) Karen Nuytemans et al.   HUMAN MUTATION

DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex

(2010) Joo-Young Im et al.   NEUROSCIENCE RESEARCH

Phenotypic Covariance of Longevity, Immunity and Stress Resistance in the Caenorhabditis Nematodes

(2010) Francis R. G. Amrit et al.   PLoS One

Stressed-Induced TMEM135 Protein Is Part of a Conserved Genetic Network Involved in Fat Storage and Longevity Regulation in Caenorhabditis elegans

(2010) Vernat J. Exil et al.   PLoS One

DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway

(2010) H. Aleyasin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1

(2009) Sang-Kyu Park et al.   AGING CELL

Manganese-Induced Dopaminergic Neurodegeneration: Insights into Mechanisms and Genetics Shared with Parkinson’s Disease

(2009) Alexandre Benedetto et al.   CHEMICAL REVIEWS

DJ-1is a Parkinson's disease susceptibility gene in southern Italy

(2009) EV De Marco et al.   CLINICAL GENETICS

DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders

(2009) Philipp J. Kahle et al.   FREE RADICAL BIOLOGY AND MEDICINE

Stimulation of Movement in a Quiescent, Hibernation-Like Form of Caenorhabditis elegans by Dopamine Signaling

(2009) M. M. Gaglia et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial respiratory chain dysfunction variably increases oxidant stress in Caenorhabditis elegans

(2009) Stephen Dingley et al.   MITOCHONDRION

Caenorhabditis elegans in Parkinson's Disease Drug Discovery: Addressing an Unmet Medical Need

(2009) R. Nass et al.   MOLECULAR INTERVENTIONS

Manganese and its Role in Parkinson’s Disease: From Transport to Neuropathology

(2009) Michael Aschner et al.   NEUROMOLECULAR MEDICINE

SMF-1, SMF-2 and SMF-3 DMT1 Orthologues Regulate and Are Regulated Differentially by Manganese Levels in C. elegans

(2009) Catherine Au et al.   PLoS One

Oxidative damage and neurodegeneration in manganese-induced neurotoxicity

(2009) Dejan Milatovic et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1

(2008) Deepti Malhotra et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson’s disease

(2008) Fang Liu et al.   JOURNAL OF NEUROCHEMISTRY

The black stuff and Konstantin Nikolaevich Tretiakoff

(2008) Andrew J. Lees et al.   MOVEMENT DISORDERS

Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology

(2008) Maxwell C. K. Leung et al.   TOXICOLOGICAL SCIENCES