Ablation of Perlecan Domain 1 Heparan Sulfate Reduces Progressive Cartilage Degradation, Synovitis, and Osteophyte Size in a Preclinical Model of Posttraumatic Osteoarthritis
出版年份 2016 全文链接
标题
Ablation of Perlecan Domain 1 Heparan Sulfate Reduces Progressive Cartilage Degradation, Synovitis, and Osteophyte Size in a Preclinical Model of Posttraumatic Osteoarthritis
作者
关键词
-
出版物
Arthritis & Rheumatology
Volume 68, Issue 4, Pages 868-879
出版商
Wiley
发表日期
2015-12-05
DOI
10.1002/art.39529
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Chondrocyte clusters adjacent to sites of cartilage degeneration have characteristics of progenitor cells
- (2015) Yoshiaki Hoshiyama et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- The Fibroblast Growth Factor signaling pathway
- (2015) David M. Ornitz et al. Wiley Interdisciplinary Reviews-Developmental Biology
- Deficiency in Perlecan/HSPG2 During Bone Development Enhances Osteogenesis and Decreases Quality of Adult Bone in Mice
- (2014) Dylan A. Lowe et al. CALCIFIED TISSUE INTERNATIONAL
- The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling
- (2014) Megan S. Lord et al. MATRIX BIOLOGY
- Depletion of Protease-Activated Receptor 2 but Not Protease-Activated Receptor 1 May Confer Protection Against Osteoarthritis in Mice Through Extracartilaginous Mechanisms
- (2014) Miriam T. Jackson et al. Arthritis & Rheumatology
- Intraarticular Sprifermin (Recombinant Human Fibroblast Growth Factor 18) in Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Trial
- (2014) L. Stefan Lohmander et al. Arthritis & Rheumatology
- Fibroblast Growth Factor 2 Drives Changes in Gene Expression Following Injury to Murine Cartilage In Vitro and In Vivo
- (2013) Ka-Wing Chong et al. ARTHRITIS AND RHEUMATISM
- Synovial perlecan is required for osteophyte formation in knee osteoarthritis
- (2013) Haruka Kaneko et al. MATRIX BIOLOGY
- Post-traumatic osteoarthritis: from mouse models to clinical trials
- (2013) Christopher B. Little et al. Nature Reviews Rheumatology
- Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice
- (2012) Tujun Weng et al. ARTHRITIS AND RHEUMATISM
- Chondroitin sulphate and heparan sulphate sulphation motifs and their proteoglycans are involved in articular cartilage formation during human foetal knee joint development
- (2012) James Melrose et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Fibroblast growth factor-2 promotes catabolism via FGFR1-Ras-Raf-MEK1/2-ERK1/2 axis that coordinates with the PKCδ pathway in human articular chondrocytes
- (2012) Dongyao Yan et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Species-specific biological effects of FGF-2 in articular cartilage: Implication for distinct roles within the FGF receptor family
- (2012) Xin Li et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Fibroblast growth factor control of cartilage homeostasis
- (2012) M.B. Ellman et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- A biomechanical role for perlecan in the pericellular matrix of articular cartilage
- (2012) Rebecca E. Wilusz et al. MATRIX BIOLOGY
- Correlation between plasma and synovial fluid basic fibroblast growth factor with radiographic severity in primary knee osteoarthritis
- (2011) Sittisak Honsawek et al. INTERNATIONAL ORTHOPAEDICS
- Fibroblast growth factor 2: good or bad guy in the joint?
- (2011) Tonia L Vincent ARTHRITIS RESEARCH & THERAPY
- Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes
- (2011) Dongyao Yan et al. ARTHRITIS RESEARCH & THERAPY
- Heparan Sulfate-Dependent Signaling of Fibroblast Growth Factor 18 by Chondrocyte-Derived Perlecan
- (2010) Christine Y. Chuang et al. BIOCHEMISTRY
- Disruption of the Fgf2 gene activates the adipogenic and suppresses the osteogenic program in mesenchymal marrow stromal stem cells
- (2010) Liping Xiao et al. BONE
- Comparative immunolocalisation of perlecan with collagen II and aggrecan in human foetal, newborn and adult ovine joint tissues demonstrates perlecan as an early developmental chondrogenic marker
- (2010) Susan M. Smith et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Fibroblast growth factor 2 is an intrinsic chondroprotective agent that suppresses ADAMTS-5 and delays cartilage degradation in murine osteoarthritis
- (2009) Shi-Lu Chia et al. ARTHRITIS AND RHEUMATISM
- Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis
- (2009) Frank Echtermeyer et al. NATURE MEDICINE
- Diverse Cell Signaling Events Modulated by Perlecan†
- (2008) John M. Whitelock et al. BIOCHEMISTRY
- Perlecan, the “jack of all trades” proteoglycan of cartilaginous weight-bearing connective tissues
- (2008) James Melrose et al. BIOESSAYS
- Reduced expression and function of bone morphogenetic protein-2 in bones of Fgf2 null mice
- (2007) Takahiro Naganawa et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The major basement membrane components localize to the chondrocyte pericellular matrix — A cartilage basement membrane equivalent?
- (2007) Alexander J. Kvist et al. MATRIX BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now