Intraarticular Sprifermin (Recombinant Human Fibroblast Growth Factor 18) in Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Trial

Magnetic Resonance Imaging-Based Three-Dimensional Bone Shape of the Knee Predicts Onset of Knee Osteoarthritis: Data From the Osteoarthritis Initiative

(2013) Tuhina Neogi et al.   ARTHRITIS AND RHEUMATISM

Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial

(2012) Jean-Yves Reginster et al.   ANNALS OF THE RHEUMATIC DISEASES

Quantitative MRI measures of cartilage predict knee replacement: a case–control study from the Osteoarthritis Initiative

(2012) Felix Eckstein et al.   ANNALS OF THE RHEUMATIC DISEASES

A 2-year randomised, double-blind, placebo-controlled, multicentre study of oral selective iNOS inhibitor, cindunistat (SD-6010), in patients with symptomatic osteoarthritis of the knee

(2012) Marie-Pierre Hellio le Graverand et al.   ANNALS OF THE RHEUMATIC DISEASES

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Theo Vos et al.   LANCET

Recent advances in osteoarthritis imaging—the Osteoarthritis Initiative

(2012) Felix Eckstein et al.   Nature Reviews Rheumatology

Predictive validity of within-grade scoring of longitudinal changes of MRI-based cartilage morphology and bone marrow lesion assessment in the tibio-femoral joint – the MOST study

(2012) F.W. Roemer et al.   OSTEOARTHRITIS AND CARTILAGE

Recombinant human fibroblast growth factor-18 (rhFG18) promotes bovine articular chondrocyte proliferation and cartilage matrix production in vitro

(2012) A. Gigout et al.   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritis as a disease of mechanics

(2012) D.T. Felson   OSTEOARTHRITIS AND CARTILAGE

American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee

(2012) Marc C. Hochberg et al.   ARTHRITIS CARE & RESEARCH

Lifetime Risk and Age at Diagnosis of Symptomatic Knee Osteoarthritis in the US

(2012) Elena Losina et al.   ARTHRITIS CARE & RESEARCH

Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI

(2011) L. M. Wildi et al.   ANNALS OF THE RHEUMATIC DISEASES

Tissue structure modification in knee osteoarthritis by use of joint distraction: an open 1-year pilot study

(2011) F. Intema et al.   ANNALS OF THE RHEUMATIC DISEASES

309 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY OF rhFGF18 ADMINISTERED INTRAARTICULARLY USING SINGLE OR MULTIPLE ASCENDING DOSES IN PATIENTS WITH PRIMARY KNEE OSTEOARTHRITIS (OA), SCHEDULED FOR TOTAL KNEE REPLACEMENT

(2011) L.E. Dahlberg et al.   OSTEOARTHRITIS AND CARTILAGE

Systematic review of the concurrent and predictive validity of MRI biomarkers in OA

(2011) D.J. Hunter et al.   OSTEOARTHRITIS AND CARTILAGE

Responsiveness and reliability of MRI in knee osteoarthritis: a meta-analysis of published evidence

(2011) D.J. Hunter et al.   OSTEOARTHRITIS AND CARTILAGE

Pharmacologic therapy for osteoarthritis—the era of disease modification

(2010) David J. Hunter   Nature Reviews Rheumatology

OARSI recommendations for the management of hip and knee osteoarthritis

(2010) W. Zhang et al.   OSTEOARTHRITIS AND CARTILAGE

Comparison of 1-year vs 2-year change in regional cartilage thickness in osteoarthritis results from 346 participants from the Osteoarthritis Initiative

(2010) W. Wirth et al.   OSTEOARTHRITIS AND CARTILAGE

Long-term effects of chondroitins 4 and 6 sulfate on knee osteoarthritis: The study on osteoarthritis progression prevention, a two-year, randomized, double-blind, placebo-controlled trial

(2009) André Kahan et al.   ARTHRITIS AND RHEUMATISM

OA clinical trials: current targets and trials for OA. Choosing molecular targets: what have we learned and where we are headed?

(2009) M.-P. Hellio Le Graverand-Gastineau   OSTEOARTHRITIS AND CARTILAGE

Developments in the clinical understanding of osteoarthritis

(2009) David T Felson   ARTHRITIS RESEARCH & THERAPY

Precision of 3.0 Tesla quantitative magnetic resonance imaging of cartilage morphology in a multicentre clinical trial

(2008) F Eckstein et al.   ANNALS OF THE RHEUMATIC DISEASES

Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI

(2008) J-P Raynauld et al.   ANNALS OF THE RHEUMATIC DISEASES

One year change of knee cartilage morphology in the first release of participants from the Osteoarthritis Initiative progression subcohort: association with sex, body mass index, symptoms and radiographic osteoarthritis status

(2008) F Eckstein et al.   ANNALS OF THE RHEUMATIC DISEASES

Patterns of femorotibial cartilage loss in knees with neutral, varus, and valgus alignment

(2008) Felix Eckstein et al.   ARTHRITIS AND RHEUMATISM

A Technique for Regional Analysis of Femorotibial Cartilage Thickness Based on Quantitative Magnetic Resonance Imaging

(2008) W. Wirth et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort

(2008) W. Wirth et al.   OSTEOARTHRITIS AND CARTILAGE