Autophagy and autophagy dysfunction contribute to apoptosis in HepG2 cells exposed to nanosilica

Magnetic ferroferric oxide nanoparticles induce vascular endothelial cell dysfunction and inflammation by disturbing autophagy

(2016) Lu Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

Bio-functionalized dense-silica nanoparticles for MR/NIRF imaging of CD146 in gastric cancer

(2015) Pu Wang et al.   International Journal of Nanomedicine

Single peptide ligand-functionalized uniform hollow mesoporous silica nanoparticles achieving dual-targeting drug delivery to tumor cells and angiogenic blood vessel cells

(2015) Yang Liu et al.   International Journal of Nanomedicine

Mesoporous silica nanoparticles in drug delivery and biomedical applications

(2015) Ying Wang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Cationic polystyrene nanospheres induce autophagic cell death through the induction of endoplasmic reticulum stress

(2015) Hui-Wen Chiu et al.   Nanoscale

Mechanism of autophagic regulation in carcinogenesis and cancer therapeutics

(2015) Prashanta Kumar Panda et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Autophagy as the effector and player in DNA damage response of cells to genotoxicants

(2015) Shi-Meng Zhang et al.   Toxicology Research

Role for nanomaterial-autophagy interaction in neurodegenerative disease

(2014) Stephan T. Stern et al.   Autophagy

The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers

(2014) Shaofei Wang et al.   BIOMATERIALS

Presence of nanosilica (E551) in commercial food products: TNF-mediated oxidative stress and altered cell cycle progression in human lung fibroblast cells

(2014) Jegan Athinarayanan et al.   CELL BIOLOGY AND TOXICOLOGY

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

(2014) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Overendocytosis of gold nanoparticles increases autophagy and apoptosis in hypoxic human renal proximal tubular cells

(2014) Fengan Ding et al.   International Journal of Nanomedicine

Synthesis, characterization, and cellular uptake of magnetic nanocarriers for cancer drug delivery

(2014) Leva Momtazi et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Silica nanoparticles induce autophagy and autophagic cell death in HepG2 cells triggered by reactive oxygen species

(2014) Yongbo Yu et al.   JOURNAL OF HAZARDOUS MATERIALS

Acute exposure to ZnO nanoparticles induces autophagic immune cell death

(2014) Brandon M. Johnson et al.   Nanotoxicology

Cytoskeleton and Chromosome Damage Leading to Abnormal Mitosis Were Involved in Multinucleated Cells Induced by Silicon Nanoparticles

(2014) Yang Li et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Metabolic control of cell death

(2014) D. R. Green et al.   SCIENCE

Formation of a Protein Corona on Silver Nanoparticles Mediates Cellular Toxicity via Scavenger Receptors

(2014) Jonathan H. Shannahan et al.   TOXICOLOGICAL SCIENCES

Magnetic iron oxide nanoparticles induce autophagy preceding apoptosis through mitochondrial damage and ER stress in RAW264.7 cells

(2014) Eun-Jung Park et al.   TOXICOLOGY IN VITRO

Zinc oxide nanoparticles induce apoptosis by enhancement of autophagy via PI3K/Akt/mTOR inhibition

(2014) Ruchi Roy et al.   TOXICOLOGY LETTERS

The Role of the Selective Adaptor p62 and Ubiquitin-Like Proteins in Autophagy

(2014) Mónika Lippai et al.   Biomed Research International

Cardiovascular toxicity evaluation of silica nanoparticles in endothelial cells and zebrafish model

(2013) Junchao Duan et al.   BIOMATERIALS

Cadmium-Based Quantum Dot Induced Autophagy Formation for Cell Survival via Oxidative Stress

(2013) Yueh-Hsia Luo et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Silica nanoparticles-induced cytotoxicity, oxidative stress and apoptosis in cultured A431 and A549 cells

(2013) Maqusood Ahamed   HUMAN & EXPERIMENTAL TOXICOLOGY

Evaluation of the toxicity of food additive silica nanoparticles on gastrointestinal cells

(2013) Yi-Xin Yang et al.   JOURNAL OF APPLIED TOXICOLOGY

p62/Sequestosome-1 Up-regulation Promotes ABT-263-induced Caspase-8 Aggregation/Activation on the Autophagosome

(2013) Shengbing Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recent development of silica nanoparticles as delivery vectors for cancer imaging and therapy

(2013) Xu Wu et al.   Nanomedicine-Nanotechnology Biology and Medicine

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(2013) B Korzeniowska et al.   NANOTECHNOLOGY

Acute Toxicity of Amorphous Silica Nanoparticles in Intravenously Exposed ICR Mice

(2013) Yang Yu et al.   PLoS One

Toxic Effect of Silica Nanoparticles on Endothelial Cells through DNA Damage Response via Chk1-Dependent G2/M Checkpoint

(2013) Junchao Duan et al.   PLoS One

Size-dependent cellular uptake efficiency, mechanism, and cytotoxicity of silica nanoparticles toward HeLa cells

(2013) Jie Zhu et al.   TALANTA

Autophagy protein p62/SQSTM1 is involved in HAMLET-induced cell death by modulating apotosis in U87MG cells

(2013) Y-B Zhang et al.   Cell Death & Disease

Cerium Dioxide Nanoparticles Induce Apoptosis and Autophagy in Human Peripheral Blood Monocytes

(2012) Salik Hussain et al.   ACS Nano

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

(2012) Stephan T Stern et al.   Particle and Fibre Toxicology

Copper Oxide Nanoparticles Induce Autophagic Cell Death in A549 Cells

(2012) Tingting Sun et al.   PLoS One

The toxicological mode of action and the safety of synthetic amorphous silica—A nanostructured material

(2012) Claudia Fruijtier-Pölloth   TOXICOLOGY

Cellular uptake, intracellular trafficking and cytotoxicity of silver nanoparticles

(2012) Raman Preet Singh et al.   TOXICOLOGY LETTERS

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(2011) Andreas Elsaesser et al.   ADVANCED DRUG DELIVERY REVIEWS

Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application

(2011) Hiromi Nabeshi et al.   BIOMATERIALS

Cytotoxicity of silica nanoparticles through exocytosis of von Willebrand factor and necrotic cell death in primary human endothelial cells

(2011) Alexander T. Bauer et al.   BIOMATERIALS

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Effects of SiO2 nanoparticles on HFL-I activating ROS-mediated apoptosis via p53 pathway

(2011) Zhengli Xu et al.   JOURNAL OF APPLIED TOXICOLOGY

Multimodal silica nanoparticles are effective cancer-targeted probes in a model of human melanoma

(2011) Miriam Benezra et al.   JOURNAL OF CLINICAL INVESTIGATION

Cytotoxicity and mitochondrial damage caused by silica nanoparticles

(2011) Lei Sun et al.   TOXICOLOGY IN VITRO

Size-dependent cytotoxicity of amorphous silica nanoparticles in human hepatoma HepG2 cells

(2011) Yang Li et al.   TOXICOLOGY IN VITRO

A functionalized single-walled carbon nanotube-induced autophagic cell death in human lung cells through Akt–TSC2-mTOR signaling

(2011) H-L Liu et al.   Cell Death & Disease

Endothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF-κB pathways

(2010) Xin Liu et al.   BIOMATERIALS

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(2010) Gaurav Sahay et al.   JOURNAL OF CONTROLLED RELEASE

Vertical Inhibition of the mTORC1/mTORC2/PI3K Pathway Shows Synergistic Effects against Melanoma In Vitro and In Vivo

(2010) Johannes Werzowa et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Presence and risks of nanosilica in food products

(2010) Susan Dekkers et al.   Nanotoxicology

The nanosilica hazard: another variable entity

(2010) Dorota Napierska et al.   Particle and Fibre Toxicology

SiO2 nanoparticles induce cytotoxicity and protein expression alteration in HaCaT cells

(2010) Xifei Yang et al.   Particle and Fibre Toxicology

Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema

(2010) Z.-H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nano-SiO2 induces apoptosis via activation of p53 and Bax mediated by oxidative stress in human hepatic cell line

(2010) Yiyi Ye et al.   TOXICOLOGY IN VITRO

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Biodistribution and toxicity of intravenously administered silica nanoparticles in mice

(2009) Guangping Xie et al.   ARCHIVES OF TOXICOLOGY

Nanocarriers’ entry into the cell: relevance to drug delivery

(2009) Hervé Hillaireau et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Silica nanoparticles as hepatotoxicants

(2009) Hikaru Nishimori et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

When apoptosis meets autophagy: deciding cell fate after trauma and sepsis

(2009) Ya-Ching Hsieh et al.   TRENDS IN MOLECULAR MEDICINE

Size-dependent hydroxyl radicals generation induced by SiO2 ultra-fine particles: The role of surface iron

(2009) Yu Shang et al.   Science in China. Series B, Chemistry

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Categorization framework to aid exposure assessment of nanomaterials in consumer products

(2008) Steffen Foss Hansen et al.   ECOTOXICOLOGY

Effect of Micro/Nano Silica Particle Feeding for Mice

(2008) Soo Jeong So et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Cellular Fate of a Modular DNA Delivery System Mediated by Silica Nanoparticles

(2005) Richard A. Gemeinhart et al.   BIOTECHNOLOGY PROGRESS