Acute exposure to ZnO nanoparticles induces autophagic immune cell death

Reducing ZnO nanoparticle cytotoxicity by surface modification

(2014) Mingdeng Luo et al.   Nanoscale

Toxicity assessment of zinc oxide nanoparticles using sub-acute and sub-chronic murine inhalation models

(2014) Andrea Adamcakova-Dodd et al.   Particle and Fibre Toxicology

Bioavailability, distribution and clearance of tracheally-instilled and gavaged uncoated or silica-coated zinc oxide nanoparticles

(2014) Nagarjun V Konduru et al.   Particle and Fibre Toxicology

Zinc oxide nanoparticles induce apoptosis by enhancement of autophagy via PI3K/Akt/mTOR inhibition

(2014) Ruchi Roy et al.   TOXICOLOGY LETTERS

Quantification of ZnO Nanoparticle Uptake, Distribution, and Dissolution within Individual Human Macrophages

(2013) Simon A. James et al.   ACS Nano

Inhibitory zinc sites in enzymes

(2013) Wolfgang Maret   BIOMETALS

Nanoparticle-induced photocatalytic head and neck squamous cell carcinoma cell death is associated with autophagy

(2013) Stephan Hackenberg et al.   Nanomedicine

Cardiopulmonary toxicity of pulmonary exposure to occupationally relevant zinc oxide nanoparticles

(2013) Hsiao-Chi Chuang et al.   Nanotoxicology

Gene Expression Profiling of Immune-Competent Human Cells Exposed to Engineered Zinc Oxide or Titanium Dioxide Nanoparticles

(2013) Soile Tuomela et al.   PLoS One

Relating Cytotoxicity, Zinc Ions, and Reactive Oxygen in ZnO Nanoparticle–Exposed Human Immune Cells

(2013) Cenchao Shen et al.   TOXICOLOGICAL SCIENCES

Zinc oxide nanoparticle induced autophagic cell death and mitochondrial damage via reactive oxygen species generation

(2013) Kyeong-Nam Yu et al.   TOXICOLOGY IN VITRO

The modality of cell–particle interactions drives the toxicity of nanosized CuO and TiO2 in human alveolar epithelial cells

(2013) Elisa Moschini et al.   TOXICOLOGY LETTERS

Use of Metal Oxide Nanoparticle Band Gap To Develop a Predictive Paradigm for Oxidative Stress and Acute Pulmonary Inflammation

(2012) Haiyuan Zhang et al.   ACS Nano

Association of zinc ion release and oxidative stress induced by intratracheal instillation of ZnO nanoparticles to rat lung

(2012) Hiroko Fukui et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Toxic effect of different ZnO particles on mouse alveolar macrophages

(2012) Jinyang Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

Self-eating and self-defense: autophagy controls innate immunity and adaptive immunity

(2012) Guangwei Liu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The effect of fluorination of zinc oxide nanoparticles on evaluation of their biodistribution after oral administration

(2012) Chang-Moon Lee et al.   NANOTECHNOLOGY

Effects of subtoxic concentrations of TiO2 and ZnO nanoparticles on human lymphocytes, dendritic cells and exosome production

(2012) Britta Andersson-Willman et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status

(2012) Morag Prach et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Decreased Dissolution of ZnO by Iron Doping Yields Nanoparticles with Reduced Toxicity in the Rodent Lung and Zebrafish Embryos

(2011) Tian Xia et al.   ACS Nano

Cell type-specific responses of peripheral blood mononuclear cells to silver nanoparticles

(2011) C. Greulich et al.   Acta Biomaterialia

Inhibition of autophagy by 3-methyladenine protects 1321N1 astrocytoma cells against pyocyanin- and 1-hydroxyphenazine-induced toxicity

(2011) Amelia J. McFarland et al.   ARCHIVES OF TOXICOLOGY

Evaluation of the cytotoxic and inflammatory potential of differentially shaped zinc oxide nanoparticles

(2011) Boon Chin Heng et al.   ARCHIVES OF TOXICOLOGY

Cell death by autophagy: facts and apparent artefacts

(2011) D Denton et al.   CELL DEATH AND DIFFERENTIATION

Dendritic Cells and CD28 Costimulation Are Required To Sustain Virus-Specific CD8+ T Cell Responses during the Effector Phase In Vivo

(2011) D. V. Dolfi et al.   JOURNAL OF IMMUNOLOGY

Aggregation and Dissolution of 4 nm ZnO Nanoparticles in Aqueous Environments: Influence of pH, Ionic Strength, Size, and Adsorption of Humic Acid

(2011) Shao-Wei Bian et al.   LANGMUIR

Organ biodistribution, clearance, and genotoxicity of orally administered zinc oxide nanoparticles in mice

(2011) Ching-Hao Li et al.   Nanotoxicology

Zinc Oxide Nanoparticles Interfere With Zinc Ion Homeostasis to Cause Cytotoxicity

(2011) Yi-Yun Kao et al.   TOXICOLOGICAL SCIENCES

Use of a Rapid Cytotoxicity Screening Approach To Engineer a Safer Zinc Oxide Nanoparticle through Iron Doping

(2010) Saji George et al.   ACS Nano

Zinc induced apoptotic death of mouse dendritic cells

(2010) Ekaterina Shumilina et al.   APOPTOSIS

Contributions of surface topography and cytotoxicity to the macrophage response to zinc oxide nanorods

(2010) Toral D. Zaveri et al.   BIOMATERIALS

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Increased level of exogenous zinc induces cytotoxicity and up-regulates the expression of the ZnT-1 zinc transporter gene in pancreatic cancer cells

(2010) Arathi K. Jayaraman et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

ZnO Nanoparticles: Synthesis, Characterization, and Ecotoxicological Studies

(2010) Roberta Brayner et al.   LANGMUIR

Role of the dissolved zinc ion and reactive oxygen species in cytotoxicity of ZnO nanoparticles

(2010) Wenhua Song et al.   TOXICOLOGY LETTERS

Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis

(2009) Mehrdad Alirezaei et al.   Autophagy

Comparison of inhibitory activities of zinc oxide ultrafine and fine particulates on IgE-induced mast cell activation

(2009) Kouya Yamaki et al.   BIOMETALS

Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy

(2009) O. Zabirnyk et al.   CARCINOGENESIS

Superoxide is the major reactive oxygen species regulating autophagy

(2009) Y Chen et al.   CELL DEATH AND DIFFERENTIATION

The Influences of Cell Type and ZnO Nanoparticle Size on Immune Cell Cytotoxicity and Cytokine Induction

(2009) Cory Hanley et al.   Nanoscale Research Letters

Engineered nanomaterials cause cytotoxicity and activation on mouse antigen presenting cells

(2009) J. Palomäki et al.   TOXICOLOGY

Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

(2008) Tian Xia et al.   ACS Nano

Intracellular zinc homeostasis and zinc signaling

(2008) Masaaki Murakami et al.   CANCER SCIENCE

Toxicity of nano- and micro-sized ZnO particles in human lung epithelial cells

(2008) Weisheng Lin et al.   JOURNAL OF NANOPARTICLE RESEARCH

Preferential killing of cancer cells and activated human T cells using ZnO nanoparticles

(2008) Cory Hanley et al.   NANOTECHNOLOGY

Promotion of autophagy and inhibition of apoptosis by low concentrations of cadmium in vascular endothelial cells

(2008) Zhiwu Dong et al.   TOXICOLOGY IN VITRO