标题
Regulation of TAZ in cancer
作者
关键词
TAZ, the Hippo pathway, cancer
出版物
Protein & Cell
Volume 7, Issue 8, Pages 548-561
出版商
Springer Nature
发表日期
2016-07-14
DOI
10.1007/s13238-016-0288-z
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- The characterisation of LATS2 kinase regulation in Hippo-YAP signalling
- (2016) Lily Hoa et al. CELLULAR SIGNALLING
- Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP
- (2016) Duyen Amy Bui et al. Science Signaling
- Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP
- (2016) Duyen Amy Bui et al. Science Signaling
- MiRNA-125a-5p inhibits glioblastoma cell proliferation and promotes cell differentiation by targeting TAZ
- (2015) Jian Yuan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Upregulation of miR-130b enhances stem cell-like phenotype in glioblastoma by inactivating the Hippo signaling pathway
- (2015) Guohua Zhu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- TAZ promotes temozolomide resistance by upregulating MCL-1 in human glioma cells
- (2015) Tian Tian et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- miR-9-3p plays a tumour-suppressor role by targeting TAZ (WWTR1) in hepatocellular carcinoma cells
- (2015) T Higashi et al. BRITISH JOURNAL OF CANCER
- Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
- (2015) Fa-Xing Yu et al. CELL
- Energy crisis and the Hippo pathway
- (2015) Wenqi Wang et al. CELL CYCLE
- A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis
- (2015) Shuying Shen et al. CELL RESEARCH
- Identification of Happyhour/MAP4K as Alternative Hpo/Mst-like Kinases in the Hippo Kinase Cascade
- (2015) Yonggang Zheng et al. DEVELOPMENTAL CELL
- Aerobic glycolysis tunes YAP/TAZ transcriptional activity
- (2015) E. Enzo et al. EMBO JOURNAL
- A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis
- (2015) Toshiro Moroishi et al. GENES & DEVELOPMENT
- Photoactivation of TAZ via Akt/GSK3β signaling pathway promotes osteogenic differentiation
- (2015) Jie Feng et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Hippo Component TAZ Functions as a Co-repressor and Negatively Regulates ΔNp63Transcription through TEA Domain (TEAD) Transcription Factor
- (2015) Ivette Valencia-Sama et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Estrogen regulates Hippo signaling via GPER in breast cancer
- (2015) Xin Zhou et al. JOURNAL OF CLINICAL INVESTIGATION
- A YAP/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell Carcinoma
- (2015) S. E. Hiemer et al. MOLECULAR CANCER RESEARCH
- The Hippo transducer TAZ promotes epithelial to mesenchymal transition and cancer stem cell maintenance in oral cancer
- (2015) Zhongwu Li et al. Molecular Oncology
- Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway
- (2015) Jung-Soon Mo et al. NATURE CELL BIOLOGY
- Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth
- (2015) Francesca Zanconato et al. NATURE CELL BIOLOGY
- AMPK modulates Hippo pathway activity to regulate energy homeostasis
- (2015) Wenqi Wang et al. NATURE CELL BIOLOGY
- Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein
- (2015) M R Tanas et al. ONCOGENE
- Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1
- (2015) Huabing Zhang et al. Science Signaling
- YAP and TAZ: a nexus for Hippo signaling and beyond
- (2015) Carsten Gram Hansen et al. TRENDS IN CELL BIOLOGY
- MicroRNA-141 inhibits tumor growth and metastasis in gastric cancer by directly targeting transcriptional co-activator with PDZ-binding motif, TAZ
- (2015) Q-F Zuo et al. Cell Death & Disease
- MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway
- (2015) Zhipeng Meng et al. Nature Communications
- HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells
- (2015) Lisha Xiang et al. Oncotarget
- A novel role for microRNA-129-5p in inhibiting ovarian cancer cell proliferation and survival via direct suppression of transcriptional co-activators YAP and TAZ
- (2015) Guosheng Tan et al. Oncotarget
- Regulation of sensitivity of tumor cells to antitubulin drugs by Cdk1-TAZ signalling
- (2015) Yulei Zhao et al. Oncotarget
- Up-regulation of the Hippo pathway effector TAZ renders lung adenocarcinoma cells harboring EGFR-T790M mutation resistant to gefitinib
- (2015) Wei Xu et al. Cell and Bioscience
- Transcriptional Co-repressor Function of the Hippo Pathway Transducers YAP and TAZ
- (2015) Minchul Kim et al. Cell Reports
- Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1
- (2015) Huabing Zhang et al. Science Signaling
- The Hippo transducer TAZ as a biomarker of pathological complete response in HER2-positive breast cancer patients treated with trastuzumab-based neoadjuvant therapy
- (2015) Patrizia Vici et al. Oncotarget
- Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype
- (2015) Lisha Xiang et al. Oncotarget
- G protein-coupled receptors: bridging the gap from the extracellular signals to the Hippo pathway
- (2014) X. Zhou et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Hypoxic conditions differentially regulate TAZ and YAP in cancer cells
- (2014) Libo Yan et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Mutant Gq/11 Promote Uveal Melanoma Tumorigenesis by Activating YAP
- (2014) Fa-Xing Yu et al. CANCER CELL
- Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry
- (2014) Xiaodong Feng et al. CANCER CELL
- A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer
- (2014) Shi Jiao et al. CANCER CELL
- Hippo Signaling Regulates Microprocessor and Links Cell-Density-Dependent miRNA Biogenesis to Cancer
- (2014) Masaki Mori et al. CELL
- VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex
- (2014) Wenjing Zhang et al. CELL RESEARCH
- An Integrative Analysis of the Tumorigenic Role of TAZ in Human Non-Small Cell Lung Cancer
- (2014) S. Noguchi et al. CLINICAL CANCER RESEARCH
- Sensing the local environment: actin architecture and Hippo signalling
- (2014) Pedro Gaspar et al. CURRENT OPINION IN CELL BIOLOGY
- The Conserved Misshapen-Warts-Yorkie Pathway Acts in Enteroblasts to Regulate Intestinal Stem Cells in Drosophila
- (2014) Qi Li et al. DEVELOPMENTAL CELL
- Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis
- (2014) A. N. Lau et al. EMBO JOURNAL
- Metabolic control of YAP and TAZ by the mevalonate pathway
- (2014) Giovanni Sorrentino et al. NATURE CELL BIOLOGY
- Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathway
- (2014) G Liu et al. ONCOGENE
- TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells
- (2014) M Bartucci et al. ONCOGENE
- Energy Stress Regulates Hippo-YAP Signaling Involving AMPK-Mediated Regulation of Angiomotin-like 1 Protein
- (2014) Michael DeRan et al. Cell Reports
- CDK1 Phosphorylation of YAP Promotes Mitotic Defects and Cell Motility and Is Essential for Neoplastic Transformation
- (2013) S. Yang et al. CANCER RESEARCH
- Hypoxia inducible factor-1 is activated by transcriptional co-activator with PDZ-binding motif (TAZ) versus WWdomain-containing oxidoreductase (WWOX) in hypoxic microenvironment of bone metastasis from breast cancer
- (2013) Paola Bendinelli et al. EUROPEAN JOURNAL OF CANCER
- Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation
- (2013) F.-X. Yu et al. GENES & DEVELOPMENT
- The Hippo pathway: regulators and regulations
- (2013) F.-X. Yu et al. GENES & DEVELOPMENT
- Overexpression of Hippo pathway effector TAZ in tongue squamous cell carcinoma: correlation with clinicopathological features and patients' prognosis
- (2013) Zicheng Wei et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- TAZ Expression as a Prognostic Indicator in Colorectal Cancer
- (2013) Hiu-Fung Yuen et al. PLoS One
- Overexpression of YAP and TAZ Is an Independent Predictor of Prognosis in Colorectal Cancer and Related to the Proliferation and Metastasis of Colon Cancer Cells
- (2013) Lijuan Wang et al. PLoS One
- Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility
- (2013) Z. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutual regulation between Hippo signaling and actin cytoskeleton
- (2013) Yurika Matsui et al. Protein & Cell
- Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling
- (2012) Fa-Xing Yu et al. CELL
- TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin
- (2012) Nuo Yang et al. CELL CYCLE
- Identification of Serum-Derived Sphingosine-1-Phosphate as a Small Molecule Regulator of YAP
- (2012) Eric Miller et al. CHEMISTRY & BIOLOGY
- Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)
- (2012) J.-S. Mo et al. GENES & DEVELOPMENT
- Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
- (2012) Y. Liu-Chittenden et al. GENES & DEVELOPMENT
- Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
- (2012) B. Zhao et al. GENES & DEVELOPMENT
- The N-terminal Phosphodegron Targets TAZ/WWTR1 Protein for SCFβ-TrCP-dependent Degradation in Response to Phosphatidylinositol 3-Kinase Inhibition
- (2012) Wei Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prognostic Significance of TAZ Expression in Resected Non-Small Cell Lung Cancer
- (2012) Mian Xie et al. Journal of Thoracic Oncology
- TAZ Suppresses NFAT5 Activity through Tyrosine Phosphorylation
- (2012) E. J. Jang et al. MOLECULAR AND CELLULAR BIOLOGY
- Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia
- (2012) S. J. Conley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structures of YAP protein domains reveal promising targets for development of new cancer drugs
- (2012) Marius Sudol et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells
- (2011) Michelangelo Cordenonsi et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- MOB control: Reviewing a conserved family of kinase regulators
- (2011) Alexander Hergovich CELLULAR SIGNALLING
- The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma
- (2011) K. P. L. Bhat et al. GENES & DEVELOPMENT
- A novel WWTR1-CAMTA1 gene fusion is a consistent abnormality in epithelioid hemangioendothelioma of different anatomic sites
- (2011) Costantino Errani et al. GENES CHROMOSOMES & CANCER
- A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription
- (2011) Y. Bao et al. JOURNAL OF BIOCHEMISTRY
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- TAZ is a novel oncogene in non-small cell lung cancer
- (2011) Z Zhou et al. ONCOGENE
- Identification of a Disease-Defining Gene Fusion in Epithelioid Hemangioendothelioma
- (2011) M. R. Tanas et al. Science Translational Medicine
- Overexpression of yes-associated protein contributes to progression and poor prognosis of non-small-cell lung cancer
- (2010) Yang Wang et al. CANCER SCIENCE
- The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway
- (2010) Xaralabos Varelas et al. DEVELOPMENTAL CELL
- TAZ as a novel enhancer of MyoD-mediated myogenic differentiation
- (2010) Hana Jeong et al. FASEB JOURNAL
- TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner
- (2010) Eline Remue et al. FEBS LETTERS
- The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version
- (2010) B. Zhao et al. GENES & DEVELOPMENT
- A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF -TRCP
- (2010) B. Zhao et al. GENES & DEVELOPMENT
- The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCFβ-TrCPE3 Ligase
- (2010) Chen-Ying Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PP1 Cooperates with ASPP2 to Dephosphorylate and Activate TAZ
- (2010) Chen-Ying Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Diverse somatic mutation patterns and pathway alterations in human cancers
- (2010) Zhengyan Kan et al. NATURE
- WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ
- (2010) S W Chan et al. ONCOGENE
- TEADs Mediate Nuclear Retention of TAZ to Promote Oncogenic Transformation
- (2009) Siew Wee Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition
- (2009) Heng Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Role for TAZ in Migration, Invasion, and Tumorigenesis of Breast Cancer Cells
- (2008) S. W. Chan et al. CANCER RESEARCH
- The Hippo–YAP pathway: new connections between regulation of organ size and cancer
- (2008) Bin Zhao et al. CURRENT OPINION IN CELL BIOLOGY
- TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation
- (2008) Tina Di Palma et al. EXPERIMENTAL CELL RESEARCH
- TAZ Promotes Cell Proliferation and Epithelial-Mesenchymal Transition and Is Inhibited by the Hippo Pathway
- (2008) Q.-Y. Lei et al. MOLECULAR AND CELLULAR BIOLOGY
- TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
- (2008) Xaralabos Varelas et al. NATURE CELL BIOLOGY
- PI3K pathway alterations in cancer: variations on a theme
- (2008) T L Yuan et al. ONCOGENE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now