Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1
出版年份 2015 全文链接
标题
Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1
作者
关键词
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出版物
Science Signaling
Volume 8, Issue 397, Pages ra98-ra98
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2015-10-07
DOI
10.1126/scisignal.aac5418
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A gp130–Src–YAP module links inflammation to epithelial regeneration
- (2015) Koji Taniguchi et al. NATURE
- Phase I/II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer
- (2014) M T Huggett et al. BRITISH JOURNAL OF CANCER
- Cancer statistics, 2014
- (2014) Rebecca Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Mutant Gq/11 Promote Uveal Melanoma Tumorigenesis by Activating YAP
- (2014) Fa-Xing Yu et al. CANCER CELL
- Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry
- (2014) Xiaodong Feng et al. CANCER CELL
- Hippo Coactivator YAP1 Upregulates SOX9 and Endows Esophageal Cancer Cells with Stem-like Properties
- (2014) S. Song et al. CANCER RESEARCH
- YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response
- (2014) Luca Azzolin et al. CELL
- The clinically used photosensitizer Verteporfin (VP) inhibits YAP-TEAD and human retinoblastoma cell growth in vitro without light activation
- (2014) Katarzyna Brodowska et al. EXPERIMENTAL EYE RESEARCH
- YAP activation is an early event and a potential therapeutic target in liver cancer development
- (2014) Andrea Perra et al. JOURNAL OF HEPATOLOGY
- ProteomeXchange provides globally coordinated proteomics data submission and dissemination
- (2014) Juan A Vizcaíno et al. NATURE BIOTECHNOLOGY
- In vivo quantitative phosphoproteomic profiling identifies novel regulators of castration-resistant prostate cancer growth
- (2014) N Jiang et al. ONCOGENE
- Induction of Covalently Crosslinked p62 Oligomers with Reduced Binding to Polyubiquitinated Proteins by the Autophagy Inhibitor Verteporfin
- (2014) Elizabeth Donohue et al. PLoS One
- Sox9 Induction, Ectopic Paneth Cells, and Mitotic Spindle Axis Defects in Mouse Colon Adenomatous Epithelium Arising From Conditional Biallelic Apc Inactivation
- (2013) Ying Feng et al. AMERICAN JOURNAL OF PATHOLOGY
- Intestinal Regeneration: YAP—Tumor Suppressor and Oncoprotein?
- (2013) Vivian S.W. Li et al. CURRENT BIOLOGY
- Endothelial PAS Domain Protein 1 Activates the Inflammatory Response in the Intestinal Epithelium to Promote Colitis in Mice
- (2013) Xiang Xue et al. GASTROENTEROLOGY
- Lamin aggregation is an early sensor of porphyria-induced liver injury
- (2013) A. Singla et al. JOURNAL OF CELL SCIENCE
- Human colonic crypts in culture: segregation of immunochemical markers in normal versus adenoma-derived
- (2013) Michael K Dame et al. LABORATORY INVESTIGATION
- Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer
- (2013) Balázs Győrffy et al. PLoS One
- Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma
- (2012) Y.-L. Hu et al. CANCER RESEARCH
- β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis
- (2012) Joseph Rosenbluh et al. CELL
- Role of TAZ as Mediator of Wnt Signaling
- (2012) Luca Azzolin et al. CELL
- YAP oncogene overexpression supercharges colon cancer proliferation
- (2012) Joseph Avruch et al. CELL CYCLE
- Evaluation of verteporfin pharmakokinetics – redefining the need of photosensitizers in ophthalmology
- (2012) Focke Ziemssen et al. Expert Opinion on Drug Metabolism & Toxicology
- Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
- (2012) Y. Liu-Chittenden et al. GENES & DEVELOPMENT
- Oxidative stress, Nrf2 and keratin up-regulation associate with Mallory-Denk body formation in mouse erythropoietic protoporphyria
- (2012) Amika Singla et al. HEPATOLOGY
- Restriction of intestinal stem cell expansion and the regenerative response by YAP
- (2012) Evan R. Barry et al. NATURE
- Molecular Genetics of Colorectal Cancer
- (2011) Eric R. Fearon Annual Review of Pathology-Mechanisms of Disease
- Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance
- (2011) D. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program
- (2010) J. Cai et al. GENES & DEVELOPMENT
- Inhibition of Autophagosome Formation by the Benzoporphyrin Derivative Verteporfin
- (2010) Elizabeth Donohue et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis
- (2009) Julia Bollrath et al. CANCER CELL
- Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene
- (2009) Dawang Zhou et al. CANCER CELL
- IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
- (2009) Sergei Grivennikov et al. CANCER CELL
- VEGF inhibitors for the treatment of neovascular age-related macular degeneration
- (2009) Mark Rami Barakat et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Human colon tissue in organ culture: preservation of normal and neoplastic characteristics
- (2009) Michael K. Dame et al. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
- SCALLOPED Interacts with YORKIE, the Nuclear Effector of the Hippo Tumor-Suppressor Pathway in Drosophila
- (2008) Youlian Goulev et al. CURRENT BIOLOGY
- The TEAD/TEF Family Protein Scalloped Mediates Transcriptional Output of the Hippo Growth-Regulatory Pathway
- (2008) Shian Wu et al. DEVELOPMENTAL CELL
- The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control
- (2008) Lei Zhang et al. DEVELOPMENTAL CELL
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