Dimeric bis (heptyl)-Cognitin Blocks Alzheimer's β-Amyloid Neurotoxicity Via the Inhibition of Aβ Fibrils Formation and Disaggregation of Preformed Fibrils
出版年份 2015 全文链接
标题
Dimeric bis (heptyl)-Cognitin Blocks Alzheimer's β-Amyloid Neurotoxicity Via the Inhibition of Aβ Fibrils Formation and Disaggregation of Preformed Fibrils
作者
关键词
-
出版物
CNS Neuroscience & Therapeutics
Volume 21, Issue 12, Pages 953-961
出版商
Wiley
发表日期
2015-10-28
DOI
10.1111/cns.12472
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Resveratrol Protects β Amyloid-Induced Oxidative Damage and Memory Associated Proteins in H19-7 Hippocampal Neuronal Cells
- (2015) Shraddha Rege et al. Current Alzheimer Research
- Antioxidative effects of ethyl 2-(3-(benzo[d]thiazol-2-yl)ureido)acetate against amyloid β-induced oxidative cell death via NF-κB, GSK-3β and β-catenin signaling pathways in cultured cortical neurons
- (2015) E.-A. Kim et al. FREE RADICAL RESEARCH
- A newly designed molecule J2326 for Alzheimer's disease disaggregates amyloid fibrils and induces neurite outgrowth
- (2015) Pei-Teh Chang et al. NEUROPHARMACOLOGY
- Edaravone alleviates Alzheimer’s disease-type pathologies and cognitive deficits
- (2015) Shu-Sheng Jiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Protection against β-amyloid-induced synaptic and memory impairments via altering β-amyloid assembly by bis(heptyl)-cognitin
- (2015) Lan Chang et al. Scientific Reports
- Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity
- (2015) Wen-Jie Du et al. Scientific Reports
- Inhibiting β-Amyloid-Associated Alzheimer’s Pathogenesis In Vitro and In Vivo by a Multifunctional Dimeric Bis(12)-hupyridone Derived from Its Natural Analogue
- (2014) Shengquan Hu et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Amyloid-Beta Disrupts Calcium and Redox Homeostasis in Brain Endothelial Cells
- (2014) Ana Catarina R. G. Fonseca et al. MOLECULAR NEUROBIOLOGY
- A three-dimensional human neural cell culture model of Alzheimer’s disease
- (2014) Se Hoon Choi et al. NATURE
- A induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss
- (2013) M. Talantova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Treatment Strategies Targeting Amyloid -Protein
- (2013) D. Schenk et al. Cold Spring Harbor Perspectives in Medicine
- Reversal of scopolamine-induced spatial and recognition memory deficits in mice by novel multifunctional dimers bis-cognitins
- (2012) Ren-wen Han et al. BRAIN RESEARCH
- Inhibition of Choline Acetyltransferase as a Mechanism for Cholinergic Dysfunction Induced by Amyloid-β Peptide Oligomers
- (2012) Nilson Nunes-Tavares et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Adiponectin is Protective against Oxidative Stress Induced Cytotoxicity in Amyloid-Beta Neurotoxicity
- (2012) Koon-Ho Chan et al. PLoS One
- Old Drug, New Hope for Alzheimer's Disease
- (2012) W. J. Strittmatter SCIENCE
- What Drives Amyloid Molecules To Assemble into Oligomers and Fibrils?
- (2011) Jeremy D. Schmit et al. BIOPHYSICAL JOURNAL
- Protection against 1-methyl-4-phenylpyridinium ion (MPP+)-induced apoptosis by water extract of ginseng (Panax ginseng C.A. Meyer) in SH-SY5Y cells
- (2011) Shengquan Hu et al. JOURNAL OF ETHNOPHARMACOLOGY
- Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment
- (2011) A. Minarini et al. NEUROPHARMACOLOGY
- Pathologically Activated Neuroprotection via Uncompetitive Blockade ofN-Methyl-d-aspartate Receptors with Fast Off-rate by Novel Multifunctional Dimer Bis(propyl)-cognitin
- (2010) Jialie Luo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Amyloid fibrils
- (2010) Roma N. Rambaran et al. Prion
- EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
- (2010) Jan Bieschke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Huperzine A protects isolated rat brain mitochondria against β-amyloid peptide
- (2009) Xin Gao et al. FREE RADICAL BIOLOGY AND MEDICINE
- Bis(7)-tacrine, a promising anti-Alzheimer's dimer, affords dose- and time-dependent neuroprotection against transient focal cerebral ischemia
- (2008) Yuming Zhao et al. NEUROSCIENCE LETTERS
- The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine
- (2007) Hua Yu et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
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