标题
Biologics to treat substance use disorders: Current status and new directions
作者
关键词
-
出版物
Human Vaccines & Immunotherapeutics
Volume 12, Issue 12, Pages 3005-3019
出版商
Informa UK Limited
发表日期
2016-07-22
DOI
10.1080/21645515.2016.1212785
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Suppression of Cocaine-Evoked Hyperactivity by Self-Adjuvanting and Multivalent Peptide Nanofiber Vaccines
- (2016) Jai S. Rudra et al. ACS Chemical Neuroscience
- Combatting Synthetic Designer Opioids: A Conjugate Vaccine Ablates Lethal Doses of Fentanyl Class Drugs
- (2016) Paul T. Bremer et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Most microbe-specific naive CD4+ T cells produce memory cells during infection
- (2016) N. J. Tubo et al. SCIENCE
- Efficacy, but Not Antibody Titer or Affinity, of a Heroin Hapten Conjugate Vaccine Correlates with Increasing Hapten Densities on Tetanus Toxoid, but Not on CRM197 Carriers
- (2015) Rashmi Jalah et al. BIOCONJUGATE CHEMISTRY
- Synthetic Nanoparticles for Vaccines and Immunotherapy
- (2015) Darrell J. Irvine et al. CHEMICAL REVIEWS
- Effects of active anti-methamphetamine vaccination on intravenous self-administration in rats
- (2015) M.L. Miller et al. DRUG AND ALCOHOL DEPENDENCE
- Anti-nicotine vaccines: Comparison of adjuvanted CRM 197 and Qb-VLP conjugate formulations for immunogenicity and function in non-human primates
- (2015) Michael J. McCluskie et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Molecular attributes of conjugate antigen influence function of antibodies induced by anti-nicotine vaccine in mice and non-human primates
- (2015) Michael J. McCluskie et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Negatively Charged Carbon Nanohorn Supported Cationic Liposome Nanoparticles: A Novel Delivery Vehicle for Anti-Nicotine Vaccine
- (2015) Hong Zheng et al. Journal of Biomedical Nanotechnology
- Nanoparticulate STING agonists are potent lymph node–targeted vaccine adjuvants
- (2015) Melissa C. Hanson et al. JOURNAL OF CLINICAL INVESTIGATION
- Safety, pharmacokinetics, and pharmacodynamics of TV-1380, a novel mutated butyrylcholinesterase treatment for cocaine addiction, after single and multiple intramuscular injections in healthy subjects
- (2015) Orit Cohen-Barak et al. JOURNAL OF CLINICAL PHARMACOLOGY
- The Frequency of Naive and Early-Activated Hapten-Specific B Cell Subsets Dictates the Efficacy of a Therapeutic Vaccine against Prescription Opioid Abuse
- (2015) Megan Laudenbach et al. JOURNAL OF IMMUNOLOGY
- MF59 Mediates Its B Cell Adjuvanticity by Promoting T Follicular Helper Cells and Thus Germinal Center Responses in Adult and Early Life
- (2015) Beatris Mastelic Gavillet et al. JOURNAL OF IMMUNOLOGY
- Oil-in-Water Emulsion MF59 Increases Germinal Center B Cell Differentiation and Persistence in Response to Vaccination
- (2015) Giuseppe Lofano et al. JOURNAL OF IMMUNOLOGY
- Combining Active Immunization with Monoclonal Antibody Therapy To Facilitate Early Initiation of a Long-Acting Anti-Methamphetamine Antibody Response
- (2015) Michael D. Hambuchen et al. JOURNAL OF MEDICINAL CHEMISTRY
- A New Strategy for Smoking Cessation: Characterization of a Bacterial Enzyme for the Degradation of Nicotine
- (2015) Song Xue et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Flagellin as Carrier and Adjuvant in Cocaine Vaccine Development
- (2015) Jonathan W. Lockner et al. MOLECULAR PHARMACEUTICS
- Nicotine-Targeting Nano-Vaccines for Smoking Cessation
- (2015) Rajeev I Desai et al. NEUROPSYCHOPHARMACOLOGY
- Effects of the Nanoparticle-Based Vaccine, SEL-068, on Nicotine Discrimination in Squirrel Monkeys
- (2015) Rajeev I Desai et al. NEUROPSYCHOPHARMACOLOGY
- Long-acting cocaine hydrolase for addiction therapy
- (2015) Xiabin Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Apoptosis and antigen affinity limit effector cell differentiation of a single naive B cell
- (2015) J. J. Taylor et al. SCIENCE
- Biologic Approaches to Treat Substance-Use Disorders
- (2015) Phil Skolnick TRENDS IN PHARMACOLOGICAL SCIENCES
- The frequency of early-activated hapten-specific B cell subsets predicts the efficacy of vaccines for nicotine dependence
- (2015) M. Laudenbach et al. VACCINE
- New generation adjuvants – From empiricism to rational design
- (2015) Derek T. O’Hagan et al. VACCINE
- A Nanotechnology-Based Platform for Extending the Pharmacokinetic and Binding Properties of Anti-methamphetamine Antibody Fragments
- (2015) Nisha Nanaware-Kharade et al. Scientific Reports
- Characterization of a recombinant humanized anti-cocaine monoclonal antibody and its Fab fragment
- (2015) Terence L Kirley et al. Human Vaccines & Immunotherapeutics
- Efficacy of interventions to combat tobacco addiction: Cochrane update of 2013 reviews
- (2014) Jamie Hartmann-Boyce et al. ADDICTION
- Efficacy of the nicotine vaccine 3′-AmNic-rEPA (NicVAX) co-administered with varenicline and counselling for smoking cessation: a randomized placebo-controlled trial
- (2014) Philippe H. J. Hoogsteder et al. ADDICTION
- Investigating Hapten Clustering as a Strategy to Enhance Vaccines against Drugs of Abuse
- (2014) Karen C. Collins et al. BIOCONJUGATE CHEMISTRY
- Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses
- (2014) John S. Tsang et al. CELL
- Lipid tucaresol as an adjuvant for methamphetamine vaccine development
- (2014) K. C. Collins et al. CHEMICAL COMMUNICATIONS
- Amino-acid mutations to extend the biological half-life of a therapeutically valuable mutant of human butyrylcholinesterase
- (2014) Lei Fang et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Clonal and cellular dynamics in germinal centers
- (2014) Gabriel D Victora et al. CURRENT OPINION IN IMMUNOLOGY
- The future potential for cocaine vaccines
- (2014) Frank M Orson et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- T-Cell-Receptor-Dependent Signal Intensity Dominantly Controls CD4+ T Cell Polarization In Vivo
- (2014) Nicholas van Panhuys et al. IMMUNITY
- Hapten-specific naïve B cells are biomarkers of vaccine efficacy against drugs of abuse
- (2014) J.J. Taylor et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Viral Particles Drive Rapid Differentiation of Memory B Cells into Secondary Plasma Cells Producing Increased Levels of Antibodies
- (2014) F. Zabel et al. JOURNAL OF IMMUNOLOGY
- A Conjugate Vaccine Using Enantiopure Hapten Imparts Superior Nicotine-Binding Capacity
- (2014) Jonathan W. Lockner et al. JOURNAL OF MEDICINAL CHEMISTRY
- First human study of a chimeric anti-methamphetamine monoclonal antibody in healthy volunteers
- (2014) Misty W Stevens et al. mAbs
- Injection Route and TLR9 Agonist Addition Significantly Impact Heroin Vaccine Efficacy
- (2014) Paul T. Bremer et al. MOLECULAR PHARMACEUTICS
- Structure-based programming of lymph-node targeting in molecular vaccines
- (2014) Haipeng Liu et al. NATURE
- The promise and challenge of high-throughput sequencing of the antibody repertoire
- (2014) George Georgiou et al. NATURE BIOTECHNOLOGY
- Synthesis and immunological effects of heroin vaccines
- (2014) Fuying Li et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Effect of Currently Approved Carriers and Adjuvants on the Pre-Clinical Efficacy of a Conjugate Vaccine against Oxycodone in Mice and Rats
- (2014) Marco Pravetoni et al. PLoS One
- Effects of an Oxycodone Conjugate Vaccine on Oxycodone Self-Administration and Oxycodone-Induced Brain Gene Expression in Rats
- (2014) Marco Pravetoni et al. PLoS One
- Pharmacokinetic Correlates of the Effects of a Heroin Vaccine on Heroin Self-Administration in Rats
- (2014) Michael D. Raleigh et al. PLoS One
- Novel Anti-Nicotine Vaccine Using a Trimeric Coiled-Coil Hapten Carrier
- (2014) Keith D. Miller et al. PLoS One
- Vaccines, new opportunities for a new society
- (2014) R. Rappuoli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional heterogeneity of human memory CD4+ T cell clones primed by pathogens or vaccines
- (2014) S. Becattini et al. SCIENCE
- TCR signal quantity and quality in CD4+ T cell differentiation
- (2014) Noah J. Tubo et al. TRENDS IN IMMUNOLOGY
- Adjuvants for vaccines to drugs of abuse and addiction
- (2014) Carl R. Alving et al. VACCINE
- Physiologic and metabolic safety of butyrylcholinesterase gene therapy in mice
- (2014) Vishakantha Murthy et al. VACCINE
- Generation of a universal CD4 memory T cell recall peptide effective in humans, mice and non-human primates
- (2014) Christopher C. Fraser et al. VACCINE
- Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release
- (2014) Petr O. Ilyinskii et al. VACCINE
- A highly efficient cocaine-detoxifying enzyme obtained by computational design
- (2014) Fang Zheng et al. Nature Communications
- Fate of Systemically Administered Cocaine in Nonhuman Primates Treated with the dAd5GNE Anticocaine Vaccine
- (2014) Martin J. Hicks et al. Human Gene Therapy Clinical Development
- Effect of a Nicotine Vaccine on Nicotine Binding to β2*-Nicotinic Acetylcholine Receptors In Vivo in Human Tobacco Smokers
- (2013) Irina Esterlis et al. AMERICAN JOURNAL OF PSYCHIATRY
- Vaccines against stimulants: cocaine and MA
- (2013) Thomas Kosten et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Single Naive CD4+ T Cells from a Diverse Repertoire Produce Different Effector Cell Types during Infection
- (2013) Noah J. Tubo et al. CELL
- Therapeutic vaccines against tobacco addiction
- (2013) Raafat EF Fahim et al. Expert Review of Vaccines
- Prospects, promise and problems on the road to effective vaccines and related therapies for substance abuse
- (2013) Stephen Brimijoin et al. Expert Review of Vaccines
- Suppression of Nicotine-Induced Pathophysiology by an Adenovirus Hexon-Based Antinicotine Vaccine
- (2013) Jonathan B. Rosenberg et al. HUMAN GENE THERAPY
- Persistent Antigen and Germinal Center B Cells Sustain T Follicular Helper Cell Responses and Phenotype
- (2013) Dirk Baumjohann et al. IMMUNITY
- Enhancing immunogenicity of a 3′aminomethylnicotine-DT-conjugate anti-nicotine vaccine with CpG adjuvant in mice and non-human primates
- (2013) Michael J. McCluskie et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Preclinical Studies on Neurobehavioral and Neuromuscular Effects of Cocaine Hydrolase Gene Therapy in Mice
- (2013) Vishakantha Murthy et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Modulating Cocaine Vaccine Potency through Hapten Fluorination
- (2013) Xiaoqing Cai et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Probing the Effects of Hapten Stability on Cocaine Vaccine Immunogenicity
- (2013) Xiaoqing Cai et al. MOLECULAR PHARMACEUTICS
- Engineering synthetic vaccines using cues from natural immunity
- (2013) Darrell J. Irvine et al. NATURE MATERIALS
- Adenovirus Capsid-Based Anti-Cocaine Vaccine Prevents Cocaine from Binding to the Nonhuman Primate CNS Dopamine Transporter
- (2013) Anat Maoz et al. NEUROPSYCHOPHARMACOLOGY
- Niccine(R), a Nicotine Vaccine, for Relapse Prevention: A Phase II, Randomized, Placebo-Controlled, Multicenter Clinical Trial
- (2013) S. Tonstad et al. NICOTINE & TOBACCO RESEARCH
- Selection of a Novel Anti-Nicotine Vaccine: Influence of Antigen Design on Antibody Function in Mice
- (2013) David C. Pryde et al. PLoS One
- Dynamic vaccine blocks relapse to compulsive intake of heroin
- (2013) J. E. Schlosburg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A morphine conjugate vaccine attenuates the behavioral effects of morphine in rats
- (2013) Therese A. Kosten et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Accelerating Next-Generation Vaccine Development for Global Disease Prevention
- (2013) W. C. Koff et al. SCIENCE
- T Follicular Helper Cell Dynamics in Germinal Centers
- (2013) Z. Shulman et al. SCIENCE
- Increased efficacy of a trivalent nicotine vaccine compared to a dose-matched monovalent vaccine when formulated with alum
- (2013) Sabina H.L. de Villiers et al. VACCINE
- Liposomes containing monophosphoryl lipid A: A potent adjuvant system for inducing antibodies to heroin hapten analogs
- (2013) Gary R. Matyas et al. VACCINE
- Vaccination protects rats from methamphetamine-induced impairment of behavioral responding for food
- (2013) Daniela Rüedi-Bettschen et al. VACCINE
- A novel and efficient nicotine vaccine using nano-lipoplex as a delivery vehicle
- (2013) Yun Hu et al. Human Vaccines & Immunotherapeutics
- Engineering Nano- and Microparticles to Tune Immunity
- (2012) James J. Moon et al. ADVANCED MATERIALS
- Germinal Centers
- (2012) Gabriel D. Victora et al. Annual Review of Immunology
- Addiction Therapeutics: Obstacles and Opportunities
- (2012) Phil Skolnick et al. BIOLOGICAL PSYCHIATRY
- A Methamphetamine Vaccine Attenuates Methamphetamine-Induced Disruptions in Thermoregulation and Activity in Rats
- (2012) Michelle L. Miller et al. BIOLOGICAL PSYCHIATRY
- Self-assembled peptide nanofibers raising durable antibody responses against a malaria epitope
- (2012) Jai S. Rudra et al. BIOMATERIALS
- Enhancing nicotine vaccine immunogenicity with liposomes
- (2012) Jonathan W. Lockner et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The efficacy and safety of a nicotine conjugate vaccine (NicVAX®) or placebo co-administered with varenicline (Champix®) for smoking cessation: study protocol of a phase IIb, double blind, randomized, placebo controlled trial
- (2012) Philippe HJ Hoogsteder et al. BMC PUBLIC HEALTH
- Anti-cocaine antibody and butyrylcholinesterase-derived cocaine hydrolase exert cooperative effects on cocaine pharmacokinetics and cocaine-induced locomotor activity in mice
- (2012) Stephen Brimijoin et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Plants as a source of butyrylcholinesterase variants designed for enhanced cocaine hydrolase activity
- (2012) Katherine E. Larrimore et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Interception of Cocaine by Enzyme or Antibody Delivered with Viral Gene Transfer: A Novel Strategy for Preventing Relapse in Recovering Drug Users
- (2012) Stephen Brimijoin CNS & Neurological Disorders-Drug Targets
- Anti-Cocaine Vaccine Based on Coupling a Cocaine Analog to a Disrupted Adenovirus
- (2012) George Koob et al. CNS & Neurological Disorders-Drug Targets
- Developing a Vaccine Against Multiple Psychoactive Targets: A Case Study of Heroin
- (2012) G. Neil Stowe et al. CNS & Neurological Disorders-Drug Targets
- A vaccine against methamphetamine attenuates its behavioral effects in mice
- (2012) Xiaoyun Y. Shen et al. DRUG AND ALCOHOL DEPENDENCE
- Cocaine hydrolase gene therapy for cocaine abuse
- (2012) Stephen Brimijoin et al. Future Medicinal Chemistry
- Bacterial cocaine esterase: a protein-based therapy for cocaine overdose and addiction
- (2012) Diwahar Narasimhan et al. Future Medicinal Chemistry
- AAVrh.10-Mediated Expression of an Anti-Cocaine Antibody Mediates Persistent Passive Immunization That Suppresses Cocaine-Induced Behavior
- (2012) Jonathan B. Rosenberg et al. HUMAN GENE THERAPY
- Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen
- (2012) Justin J. Taylor et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A germinal center–independent pathway generates unswitched memory B cells early in the primary response
- (2012) Justin J. Taylor et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Role of Naive T Cell Precursor Frequency and Recruitment in Dictating Immune Response Magnitude
- (2012) M. K. Jenkins et al. JOURNAL OF IMMUNOLOGY
- Investigating the Effects of a Hydrolytically Stable Hapten and a Th1 Adjuvant on Heroin Vaccine Performance
- (2012) Paul T. Bremer et al. JOURNAL OF MEDICINAL CHEMISTRY
- Reduced Antinociception of Opioids in Rats and Mice by Vaccination with Immunogens Containing Oxycodone and Hydrocodone Haptens
- (2012) Marco Pravetoni et al. JOURNAL OF MEDICINAL CHEMISTRY
- A DNA Nanostructure Platform for Directed Assembly of Synthetic Vaccines
- (2012) Xiaowei Liu et al. NANO LETTERS
- A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants
- (2012) NEW ENGLAND JOURNAL OF MEDICINE
- Enhanced attenuation of nicotine discrimination in rats by combining nicotine-specific antibodies with a nicotinic receptor antagonist
- (2012) Mark G. LeSage et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Combined Cocaine Hydrolase Gene Transfer and Anti-Cocaine Vaccine Synergistically Block Cocaine-Induced Locomotion
- (2012) Marilyn E. Carroll et al. PLoS One
- AAV-Directed Persistent Expression of a Gene Encoding Anti-Nicotine Antibody for Smoking Cessation
- (2012) M. J. Hicks et al. Science Translational Medicine
- Heterogeneity in the differentiation and function of memory B cells
- (2012) Justin J. Taylor et al. TRENDS IN IMMUNOLOGY
- High immunogenicity of nicotine vaccines obtained by intradermal delivery with safe adjuvants
- (2012) Xinyuan Chen et al. VACCINE
- Co-administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats
- (2012) M. Pravetoni et al. VACCINE
- Prescription Pain Medication Dependence
- (2011) Carrie L. Dodrill et al. AMERICAN JOURNAL OF PSYCHIATRY
- Follicular Helper CD4 T Cells (TFH)
- (2011) Shane Crotty Annual Review of Immunology
- Structurally distinct nicotine immunogens elicit antibodies with non-overlapping specificities
- (2011) M. Pravetoni et al. BIOCHEMICAL PHARMACOLOGY
- Biochemical and biological characteristics of cross-reacting material 197 (CRM197), a non-toxic mutant of diphtheria toxin: Use as a conjugation protein in vaccines and other potential clinical applications
- (2011) Michael Bröker et al. BIOLOGICALS
- Vaccines Against Drug Abuse
- (2011) X Y Shen et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Immunogenicity and Smoking-Cessation Outcomes for a Novel Nicotine Immunotherapeutic
- (2011) D K Hatsukami et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Virus-like particles induce robust human T-helper cell responses
- (2011) Marion Braun et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The long-term potential of biodegradable poly(lactideco-glycolide) microparticles as the next-generation vaccine adjuvant
- (2011) Siddhartha Jain et al. Expert Review of Vaccines
- Combined active and passive immunization against nicotine: Minimizing monoclonal antibody requirements using a target antibody concentration strategy
- (2011) Katherine E. Cornish et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- A Vaccine Strategy that Induces Protective Immunity against Heroin
- (2011) G. Neil Stowe et al. JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis of Mercapto-(+)-methamphetamine Haptens and Their Use for Obtaining Improved Epitope Density on (+)-Methamphetamine Conjugate Vaccines
- (2011) F. Ivy Carroll et al. JOURNAL OF MEDICINAL CHEMISTRY
- A morphine/heroin vaccine with new hapten design attenuates behavioral effects in rats
- (2011) Qian-Qian Li et al. JOURNAL OF NEUROCHEMISTRY
- Impact of Distinct Chemical Structures for the Development of a Methamphetamine Vaccine
- (2011) Amira Y. Moreno et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Long-Lasting Effects of a PEGylated Mutant Cocaine Esterase (CocE) on the Reinforcing and Discriminative Stimulus Effects of Cocaine in Rats
- (2011) Gregory T Collins et al. NEUROPSYCHOPHARMACOLOGY
- First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children
- (2011) NEW ENGLAND JOURNAL OF MEDICINE
- Different B Cell Populations Mediate Early and Late Memory During an Endogenous Immune Response
- (2011) K. A. Pape et al. SCIENCE
- On the Composition of the Preimmune Repertoire of T Cells Specific for Peptide–Major Histocompatibility Complex Ligands
- (2010) Marc K. Jenkins et al. Annual Review of Immunology
- Using T. brucei as a biological epitope-display platform to elicit specific antibody responses
- (2010) Pete Stavropoulos et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Negative Selection and Peptide Chemistry Determine the Size of Naive Foreign Peptide-MHC Class II-Specific CD4+ T Cell Populations
- (2010) H. H. Chu et al. JOURNAL OF IMMUNOLOGY
- Carbohydrate vaccines: developing sweet solutions to sticky situations?
- (2010) Rena D. Astronomo et al. NATURE REVIEWS DRUG DISCOVERY
- A Novel Laser Vaccine Adjuvant Increases the Motility of Antigen Presenting Cells
- (2010) Xinyuan Chen et al. PLoS One
- Cocaine Vaccine for the Treatment of Cocaine Dependence in Methadone-Maintained Patients
- (2009) Bridget A. Martell et al. ARCHIVES OF GENERAL PSYCHIATRY
- Cocaine-Specific Antibodies Blunt the Subjective Effects of Smoked Cocaine in Humans
- (2009) Margaret Haney et al. BIOLOGICAL PSYCHIATRY
- Opioid dependence treatment: options in pharmacotherapy
- (2009) Angela L Stotts et al. EXPERT OPINION ON PHARMACOTHERAPY
- Human naive and memory CD4+T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells
- (2009) Rebekka Geiger et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Tracking epitope-specific T cells
- (2009) James J Moon et al. Nature Protocols
- Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire
- (2009) H. H. Chu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immune responses to methamphetamine by active immunization with peptide-based, molecular adjuvant-containing vaccines
- (2009) Michael J. Duryee et al. VACCINE
- Vaccine Adjuvants Alter TCR-Based Selection Thresholds
- (2008) Laurent Malherbe et al. IMMUNITY
- Evolution in miniature: selection, survival and distribution of antigen reactive cells in the germinal centre
- (2008) David M Tarlinton IMMUNOLOGY AND CELL BIOLOGY
- The Effect of a Chimeric Human/Murine Anti-Cocaine Monoclonal Antibody on Cocaine Self-Administration in Rats
- (2008) A. B. Norman et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Rapid cloning of high-affinity human monoclonal antibodies against influenza virus
- (2008) Jens Wrammert et al. NATURE
- A Vaccine against Nicotine for Smoking Cessation: A Randomized Controlled Trial
- (2008) Jacques Cornuz et al. PLoS One
- Isolation of human monoclonal antibodies by mammalian cell display
- (2008) R. R. Beerli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure-and-mechanism-based design and discovery of therapeutics for cocaine overdose and addiction
- (2007) Fang Zheng et al. ORGANIC & BIOMOLECULAR CHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation