Cardiovascular Disease Chemogenomics Knowledgebase-guided Target Identification and Drug Synergy Mechanism Study of an Herbal Formula
出版年份 2016 全文链接
标题
Cardiovascular Disease Chemogenomics Knowledgebase-guided Target Identification and Drug Synergy Mechanism Study of an Herbal Formula
作者
关键词
-
出版物
Scientific Reports
Volume 6, Issue 1, Pages -
出版商
Springer Nature
发表日期
2016-09-28
DOI
10.1038/srep33963
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- (2015) Zhiwei Feng et al. Journal of Chemical Information and Modeling
- The effects of modified sini decoction on liver injury and regeneration in acute liver failure induced by d-galactosamine in rats
- (2015) Jianxing Luo et al. JOURNAL OF ETHNOPHARMACOLOGY
- Comparative Pharmacokinetics of Hypaconitine after Oral Administration of Pure Hypaconitine, Aconitum carmichaelii Extract and Sini Decoction to Rats
- (2015) Wen Zhang et al. MOLECULES
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- (2015) Yu-Chian Chen TRENDS IN PHARMACOLOGICAL SCIENCES
- Small-molecule inhibitors targeting INK4 protein p18INK4C enhance ex vivo expansion of haematopoietic stem cells
- (2015) Yingdai Gao et al. Nature Communications
- Comparative pharmacokinetics of three monoester-diterpenoid alkaloids after oral administration ofAcontium carmichaeliextract and its compatibility with other herbal medicines in Sini Decoction to rats
- (2014) Hai Zhang et al. BIOMEDICAL CHROMATOGRAPHY
- Network Pharmacology in Traditional Chinese Medicine
- (2014) Shao Li et al. Evidence-based Complementary and Alternative Medicine
- AlzPlatform: An Alzheimer’s Disease Domain-Specific Chemogenomics Knowledgebase for Polypharmacology and Target Identification Research
- (2014) Haibin Liu et al. Journal of Chemical Information and Modeling
- Absorption and metabolism of three monoester-diterpenoid alkaloids in Aconitum carmichaeli after oral administration to rats by HPLC–MS
- (2014) Hai Zhang et al. JOURNAL OF ETHNOPHARMACOLOGY
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- (2014) Shujing Sheng et al. JOURNAL OF ETHNOPHARMACOLOGY
- Polypharmacology: Challenges and Opportunities in Drug Discovery
- (2014) Andrew Anighoro et al. JOURNAL OF MEDICINAL CHEMISTRY
- Investigation of the therapeutic effectiveness of active components in Sini decoction by a comprehensive GC/LC-MS based metabolomics and network pharmacology approaches
- (2014) Si Chen et al. Molecular BioSystems
- Qishenyiqi Protects Ligation-Induced Left Ventricular Remodeling by Attenuating Inflammation and Fibrosis via STAT3 and NF-κB Signaling Pathway
- (2014) Chun Li et al. PLoS One
- In silico polypharmacology: retrospective recognition vs. rational design
- (2014) Ewgenij Proschak Journal of Cheminformatics
- Chemogenomics knowledgebased polypharmacology analyses of drug abuse related G-protein coupled receptors and their ligands
- (2014) Xiang-Qun Xie et al. Frontiers in Pharmacology
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- (2014) Walmor C. De Mello Frontiers in Endocrinology
- TargetHunter: An In Silico Target Identification Tool for Predicting Therapeutic Potential of Small Organic Molecules Based on Chemogenomic Database
- (2013) Lirong Wang et al. AAPS Journal
- Renin–Angiotensin–Aldosterone System Inhibitors in Heart Failure
- (2013) F Shearer et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- The Economics of Polypharmacology: Fixed Dose Combinations and Drug Cocktails
- (2013) A. I. Wertheimer CURRENT MEDICINAL CHEMISTRY
- Liquorice, a unique “guide drug” of traditional Chinese medicine: A review of its role in drug interactions
- (2013) Xiaoying Wang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Deciphering the combination principles of Traditional Chinese Medicine from a systems pharmacology perspective based on Ma-huang Decoction
- (2013) Yao Yao et al. JOURNAL OF ETHNOPHARMACOLOGY
- The effects of Rhizoma Zingiberis on pharmacokinetics of six Aconitum alkaloids in herb couple of Radix Aconiti Lateralis−Rhizoma Zingiberis
- (2013) Wen-Wen Peng et al. JOURNAL OF ETHNOPHARMACOLOGY
- Herb-Herb Combination for Therapeutic Enhancement and Advancement: Theory, Practice and Future Perspectives
- (2013) Chun-Tao Che et al. MOLECULES
- Bioinformatics opportunities for identification and study of medicinal plants
- (2012) V. Sharma et al. BRIEFINGS IN BIOINFORMATICS
- Metabonomic Profiles Delineate the Effect of Traditional Chinese Medicine Sini Decoction on Myocardial Infarction in Rats
- (2012) Guangguo Tan et al. PLoS One
- Repulsive Guidance Molecule (RGM) Family Proteins Exhibit Differential Binding Kinetics for Bone Morphogenetic Proteins (BMPs)
- (2012) Qifang Wu et al. PLoS One
- Dose-related effects of salvinorin A in humans: dissociative, hallucinogenic, and memory effects
- (2012) Katherine A. MacLean et al. PSYCHOPHARMACOLOGY
- A new model of congestive heart failure in rats
- (2011) Jiqiu Chen et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Proteopedia entry: HMG-CoA reductase
- (2011) David Canner BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION
- Detection and identification of diterpenoid alkaloids, isoflavonoids and saponins in Qifu decoction and rat plasma by liquid chromatography-time-of-flight mass spectrometry
- (2011) Guangguo Tan et al. BIOMEDICAL CHROMATOGRAPHY
- Screening and analysis of aconitum alkaloids and their metabolites in rat urine after oral administration of aconite roots extract using LC-TOFMS-based metabolomics
- (2011) Guangguo Tan et al. BIOMEDICAL CHROMATOGRAPHY
- Computational Polypharmacology with Text Mining and Ontologies
- (2011) Conrad Plake et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
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- (2011) Chao Ma et al. Journal of Chemical Information and Modeling
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- (2011) Chao Ma et al. Journal of Chemical Information and Modeling
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- (2011) Guangguo Tan et al. Molecular BioSystems
- The structural basis for agonist and partial agonist action on a β1-adrenergic receptor
- (2011) Tony Warne et al. NATURE
- ChEMBL: a large-scale bioactivity database for drug discovery
- (2011) A. Gaulton et al. NUCLEIC ACIDS RESEARCH
- Compound Acquisition and Prioritization Algorithm for Constructing Structurally Diverse Compound Libraries
- (2011) Chao Ma et al. ACS Combinatorial Science
- Characterization of constituents in Sini decoction and rat plasma by high-performance liquid chromatography with diode array detection coupled to time-of-flight mass spectrometry
- (2010) Guangguo Tan et al. BIOMEDICAL CHROMATOGRAPHY
- Polysaccharide from Fuzi (FPS) prevents hypercholesterolemia in rats
- (2010) Xiongqing Huang et al. Lipids in Health and Disease
- Aconitum in Traditional Chinese Medicine—A valuable drug or an unpredictable risk?
- (2009) Judith Singhuber et al. JOURNAL OF ETHNOPHARMACOLOGY
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- (2009) Guangguo Tan et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
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- (2008) Jiangshan Wang et al. JOURNAL OF CHROMATOGRAPHY A
- Measurement of cardiac function using pressure–volume conductance catheter technique in mice and rats
- (2008) Pál Pacher et al. Nature Protocols
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