Investigation of the therapeutic effectiveness of active components in Sini decoction by a comprehensive GC/LC-MS based metabolomics and network pharmacology approaches

Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture

(2015) Pasha Apontes et al.   Oncotarget

Hsp70 regulates the doxorubicin-mediated heart failure in Hsp70-transgenic mice

(2014) Katerina Naka K et al.   CELL STRESS & CHAPERONES

A novel network pharmacology approach to analyse traditional herbal formulae: the Liu-Wei-Di-Huang pill as a case study

(2014) Xujun Liang et al.   Molecular BioSystems

Network pharmacology study on the mechanism of traditional Chinese medicine for upper respiratory tract infection

(2014) Xinzhuang Zhang et al.   Molecular BioSystems

Notch-1 Mediated Cardiac Protection following Embryonic and Induced Pluripotent Stem Cell Transplantation in Doxorubicin-Induced Heart Failure

(2014) Hilda Merino et al.   PLoS One

Inhibition of phosphoinositide 3-kinase γ attenuates inflammation, obesity, and cardiovascular risk factors

(2013) Matthias P. Wymann et al.   Annals of the New York Academy of Sciences

Nicorandil ameliorates mitochondrial dysfunction in doxorubicin-induced heart failure in rats: Possible mechanism of cardioprotection

(2013) Lamiaa A. Ahmed et al.   BIOCHEMICAL PHARMACOLOGY

Higenamine Combined with [6]-Gingerol Suppresses Doxorubicin-Triggered Oxidative Stress and Apoptosis in Cardiomyocytes via Upregulation of PI3K/Akt Pathway

(2013) Yan-Ling Chen et al.   Evidence-based Complementary and Alternative Medicine

Prediction of Polypharmacological Profiles of Drugs by the Integration of Chemical, Side Effect, and Therapeutic Space

(2013) Feixiong Cheng et al.   Journal of Chemical Information and Modeling

A novel concept for detoxification: Complexation between aconitine and liquiritin in a Chinese herbal formula (‘Sini Tang’)

(2013) Karoline Peter et al.   JOURNAL OF ETHNOPHARMACOLOGY

Metabolic Profiling Provides a System Understanding of Hypothyroidism in Rats and Its Application

(2013) Si Wu et al.   PLoS One

Metabolism-based synthesis, biologic evaluation and SARs analysis of O-methylated analogs of quercetin as thrombin inhibitors

(2012) Zhi-Hao Shi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Network pharmacology-based prediction of the active ingredients and potential targets of Chinese herbal Radix Curcumae formula for application to cardiovascular disease

(2012) Weiyang Tao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Prediction of chemical–protein interactions: multitarget-QSAR versus computational chemogenomic methods

(2012) Feixiong Cheng et al.   Molecular BioSystems

Therapeutic Effects of Astragaloside IV on Myocardial Injuries: Multi-Target Identification and Network Analysis

(2012) Jing Zhao et al.   PLoS One

Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference

(2012) Feixiong Cheng et al.   PLoS Computational Biology

Screening and analysis of aconitum alkaloids and their metabolites in rat urine after oral administration of aconite roots extract using LC-TOFMS-based metabolomics

(2011) Guangguo Tan et al.   BIOMEDICAL CHROMATOGRAPHY

Regulation of Kinase Cascade Activation and Heat Shock Protein Expression by Poly(ADP-ribose) Polymerase Inhibition in Doxorubicin-induced Heart Failure

(2011) Eva Bartha et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Analysis of proteome changes in doxorubicin-treated adult rat cardiomyocyte

(2011) Suresh N. Kumar et al.   Journal of Proteomics

DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical–protein interactome

(2011) Heng Luo et al.   NUCLEIC ACIDS RESEARCH

Potential Biomarkers in Mouse Myocardium of Doxorubicin-Induced Cardiomyopathy: A Metabonomic Method and Its Application

(2011) Guangguo Tan et al.   PLoS One

Characterization of constituents in Sini decoction and rat plasma by high-performance liquid chromatography with diode array detection coupled to time-of-flight mass spectrometry

(2010) Guangguo Tan et al.   BIOMEDICAL CHROMATOGRAPHY

Global metabolic profiling procedures for urine using UPLC–MS

(2010) Elizabeth J Want et al.   Nature Protocols

Discovery of drug mode of action and drug repositioning from transcriptional responses

(2010) F. Iorio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational network pharmacological research of Chinese medicinal plants for chronic kidney disease

(2010) Wei Zhu et al.   Science China-Chemistry

Metabolic remodeling associated with subchronic doxorubicin cardiomyopathy

(2010) Rui A. Carvalho et al.   TOXICOLOGY

Metabonomics study of liver cancer based on ultra performance liquid chromatography coupled to mass spectrometry with HILIC and RPLC separations

(2009) Jing Chen et al.   ANALYTICA CHIMICA ACTA

Molecular networks for the study of TCM Pharmacology

(2009) J. Zhao et al.   BRIEFINGS IN BIOINFORMATICS

Oral Glutamine Protects against Acute Doxorubicin-Induced Cardiotoxicity of Tumor-Bearing Rats

(2009) Valentina K. Todorova et al.   JOURNAL OF NUTRITION

Metabonomic Evaluation of Melamine-Induced Acute Renal Toxicity in Rats

(2009) Guoxiang Xie et al.   JOURNAL OF PROTEOME RESEARCH

Molecular Targets for Diabetes Mellitus-associated Erectile Dysfunction

(2009) Elizabeth Yohannes et al.   MOLECULAR & CELLULAR PROTEOMICS

Analysis of phenolic and triterpenoid compounds in licorice and rat plasma by high-performance liquid chromatography diode-array detection, time-of-flight mass spectrometry and quadrupole ion trap mass spectrometry

(2009) Guangguo Tan et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Chemical analysis of the Chinese herbal medicine Gan-Cao (licorice)

(2008) Qingying Zhang et al.   JOURNAL OF CHROMATOGRAPHY A

Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia

(2008) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Studies on the aconitine-type alkaloids in the roots of Aconitum Carmichaeli Debx. by HPLC/ESIMS/MSn

(2008) H YUE et al.   TALANTA