Hypocholesterolaemic Activity of Lupin Peptides: Investigation on the Crosstalk between Human Enterocytes and Hepatocytes Using a Co-Culture System Including Caco-2 and HepG2 Cells

Transepithelial transport of dry-cured ham peptides with ACE inhibitory activity through a Caco-2 cell monolayer

(2016) Marta Gallego et al.   Journal of Functional Foods

A multidisciplinary investigation on the bioavailability and activity of peptides from lupin protein

(2016) Carmen Lammi et al.   Journal of Functional Foods

Lupin protein exerts cholesterol-lowering effects targeting PCSK9: From clinical evidences to elucidation of the in vitro molecular mechanism using HepG2 cells

(2016) Carmen Lammi et al.   Journal of Functional Foods

Consuming a mixed diet enriched with lupin protein beneficially affects plasma lipids in hypercholesterolemic subjects: A randomized controlled trial

(2015) Melanie Bähr et al.   CLINICAL NUTRITION

Proprotein convertase subtilisin/kexin type 9 (PCSK9) in lipid metabolism, atherosclerosis and ischemic stroke

(2015) Lingling Zhang et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

The health benefits of sweet lupin seed flours and isolated proteins

(2015) Anna Arnoldi et al.   Journal of Functional Foods

Lipid-Lowering Drug Therapy for CVD Prevention: Looking into the Future

(2015) Evan A. Stein et al.   Current Cardiology Reports

Proprotein Convertase Subtilisin Kexin Type 9 Promotes Intestinal Overproduction of Triglyceride-Rich Apolipoprotein B Lipoproteins Through Both Low-Density Lipoprotein Receptor–Dependent and –Independent Mechanisms

(2014) Shirya Rashid et al.   CIRCULATION

PCSK9

(2014) Nabil G. Seidah et al.   CIRCULATION RESEARCH

Lupin Peptides Lower Low-Density Lipoprotein (LDL) Cholesterol through an Up-regulation of the LDL Receptor/Sterol Regulatory Element Binding Protein 2 (SREBP2) Pathway at HepG2 Cell Line

(2014) Carmen Lammi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Transintestinal Cholesterol Excretion Is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1

(2013) Cédric Le May et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

PCSK9 plays a significant role in cholesterol homeostasis and lipid transport in intestinal epithelial cells

(2013) Emile Levy et al.   ATHEROSCLEROSIS

ACE-inhibitory activity of enzymatic protein hydrolysates from lupin and other legumes

(2013) Giovanna Boschin et al.   FOOD CHEMISTRY

A protocol for differentiation of human intestinal Caco-2 cells in asymmetric serum-containing medium

(2012) Simonetta Ferruzza et al.   TOXICOLOGY IN VITRO

Hypocholesterolaemic effects of lupin protein and pea protein/fibre combinations in moderately hypercholesterolaemic individuals

(2011) Cesare R. Sirtori et al.   BRITISH JOURNAL OF NUTRITION

Hypoglycemic effect of lupin seed γ-conglutin in experimental animals and healthy human subjects

(2011) Juan C. Bertoglio et al.   FITOTERAPIA

Legumes are valuable sources of tocopherols

(2011) Giovanna Boschin et al.   FOOD CHEMISTRY

Cholesterol-lowering effect of whole lupin (Lupinus albus) seed and its protein isolate

(2011) Gustavo Guadagnucci Fontanari et al.   FOOD CHEMISTRY

Antioxidant activity and phenolic content in three lupin species

(2011) Aleksander Siger et al.   JOURNAL OF FOOD COMPOSITION AND ANALYSIS

Cell growing density affects the structural and functional properties of Caco-2 differentiated monolayer

(2010) Manuela Natoli et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Effects of lupin kernel flour–enriched bread on blood pressure: a controlled intervention study

(2009) Ya P Lee et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Proprotein Convertase Subtilisin Kexin Type 9 Null Mice Are Protected From Postprandial Triglyceridemia

(2009) Cédric Le May et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Activation of the Liver X Receptor Stimulates Trans-intestinal Excretion of Plasma Cholesterol

(2009) Jelske N. van der Veen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differing Effect of Protein Isolates from Different Cultivars of Blue Lupin on Plasma Lipoproteins of Hypercholesterolemic Rats

(2008) Anja BETTZIECHE et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Hypolipidaemic and anti-atherosclerotic effects of lupin proteins in a rabbit model

(2008) Marta Marchesi et al.   BRITISH JOURNAL OF NUTRITION