Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1α/SIRT1-dependent transcriptional regulation of mitochondrial function

Perilipin 5–Driven Lipid Droplet Accumulation in Skeletal Muscle Stimulates the Expression of Fibroblast Growth Factor 21

(2015) Lydia-Ann L.S. Harris et al.   DIABETES

Perilipin 5 improves hepatic lipotoxicity by inhibiting lipolysis

(2015) Chao Wang et al.   HEPATOLOGY

Liver Perilipin 5 Expression Worsens Hepatosteatosis But Not Insulin Resistance in High Fat-Fed Mice

(2015) Michelle B. Trevino et al.   MOLECULAR ENDOCRINOLOGY

Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21

(2015) Bryn M. Owen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Unraveling the roles of PLIN5: linking cell biology to physiology

(2015) Rachael R. Mason et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Protein Kinase A Activation Enhances β-Catenin Transcriptional Activity through Nuclear Localization to PML Bodies

(2014) Mei Zhang et al.   PLoS One

PLIN5 deletion remodels intracellular lipid composition and causes insulin resistance in muscle

(2014) Rachael R. Mason et al.   Molecular Metabolism

Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity

(2013) M. Bosma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Perilipins: Lipid droplet coat proteins adapted for tissue-specific energy storage and utilization, and lipid cytoprotection

(2013) Carole Sztalryd et al.   BIOCHIMIE

Cardiomyocyte-specific perilipin 5 overexpression leads to myocardial steatosis and modest cardiac dysfunction

(2013) Hong Wang et al.   JOURNAL OF LIPID RESEARCH

Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier

(2013) Nina M. Pollak et al.   JOURNAL OF LIPID RESEARCH

GuiTope: an application for mapping random-sequence peptides to protein sequences

(2012) Rebecca F Halperin et al.   BMC BIOINFORMATICS

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

(2012) Nathan L. Price et al.   Cell Metabolism

Role of Deleted in Breast Cancer 1 (DBC1) Protein in SIRT1 Deacetylase Activation Induced by Protein Kinase A and AMP-activated Protein Kinase

(2012) Veronica Nin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Perilipin 5, a Lipid Droplet-binding Protein, Protects Heart from Oxidative Burden by Sequestering Fatty Acid from Excessive Oxidation

(2012) Kenta Kuramoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans

(2012) Timothy R. Koves et al.   JOURNAL OF LIPID RESEARCH

Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis

(2011) Pablo J Fernandez-Marcos et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Distinct cellular pools of perilipin 5 point to roles in lipid trafficking

(2011) Sadie R. Bartholomew et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance: Another Paradox in Endurance-Trained Athletes?

(2011) F. Amati et al.   DIABETES

The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria

(2011) Madeleen Bosma et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Unique Regulation of Adipose Triglyceride Lipase (ATGL) by Perilipin 5, a Lipid Droplet-associated Protein

(2011) Hong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria

(2011) Hong Wang et al.   JOURNAL OF LIPID RESEARCH

The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD+

(2011) Zachary Gerhart-Hines et al.   MOLECULAR CELL

Dual function lipin proteins and glycerolipid metabolism

(2011) Thurl E. Harris et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Interactions of Perilipin-5 (Plin5) with Adipose Triglyceride Lipase

(2010) James G. Granneman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deleted in breast cancer–1 regulates SIRT1 activity and contributes to high-fat diet–induced liver steatosis in mice

(2010) Carlos Escande et al.   JOURNAL OF CLINICAL INVESTIGATION

Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores

(2010) Achim Lass et al.   PROGRESS IN LIPID RESEARCH

PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores

(2009) Perry E. Bickel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5

(2009) John E. Dominy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Innate Short-Circuiting of Mitochondrial Metabolism in Cardiac Hypertrophy

(2009) Michael N. Sack   CIRCULATION RESEARCH

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

(2009) Carles Cantó et al.   CURRENT OPINION IN LIPIDOLOGY

Diacylglycerol Enrichment of Endoplasmic Reticulum or Lipid Droplets Recruits Perilipin 3/TIP47 during Lipid Storage and Mobilization

(2009) James R. Skinner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt

(2008) Marcella Fulco et al.   DEVELOPMENTAL CELL

Minireview: Lipid Droplets in Lipogenesis and Lipolysis

(2008) Nicole A. Ducharme et al.   ENDOCRINOLOGY

Negative regulation of the deacetylase SIRT1 by DBC1

(2008) Wenhui Zhao et al.   NATURE