Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma
出版年份 2016 全文链接
标题
Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma
作者
关键词
-
出版物
Nature Communications
Volume 7, Issue -, Pages 12493
出版商
Springer Nature
发表日期
2016-08-25
DOI
10.1038/ncomms12493
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- TGF-β Promotes Heterogeneity and Drug Resistance in Squamous Cell Carcinoma
- (2015) Naoki Oshimori et al. CELL
- Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma
- (2015) Jessica Okosun et al. NATURE GENETICS
- High burden and pervasive positive selection of somatic mutations in normal human skin
- (2015) I. Martincorena et al. SCIENCE
- Discrepancies in Cancer Genomic Sequencing Highlight Opportunities for Driver Mutation Discovery
- (2014) A. M. Hudson et al. CANCER RESEARCH
- Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma
- (2014) C. R. Pickering et al. CLINICAL CANCER RESEARCH
- NOTCH1 Mutations Occur Early during Cutaneous Squamous Cell Carcinogenesis
- (2014) Andrew P. South et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Recurrent point mutations in the kinetochore gene KNSTRN in cutaneous squamous cell carcinoma
- (2014) Carolyn S Lee et al. NATURE GENETICS
- Mechanisms underlying mutational signatures in human cancers
- (2014) Thomas Helleday et al. NATURE REVIEWS GENETICS
- Phase I Study of GC1008 (Fresolimumab): A Human Anti-Transforming Growth Factor-Beta (TGFβ) Monoclonal Antibody in Patients with Advanced Malignant Melanoma or Renal Cell Carcinoma
- (2014) John C. Morris et al. PLoS One
- RAF Inhibitors Activate the MAPK Pathway by Relieving Inhibitory Autophosphorylation
- (2013) Matthew Holderfield et al. CANCER CELL
- The Epidermis Comprises Autonomous Compartments Maintained by Distinct Stem Cell Populations
- (2013) Mahalia E. Page et al. Cell Stem Cell
- Epithelial stem cell mutations that promote squamous cell carcinoma metastasis
- (2013) Ruth A. White et al. JOURNAL OF CLINICAL INVESTIGATION
- Methylated Tissue Factor Pathway Inhibitor 2 (TFPI2) DNA in Serum Is a Biomarker of Metastatic Melanoma
- (2013) Cristiana Lo Nigro et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Mutational Landscape of Basal Cell Carcinomas by Whole-Exome Sequencing
- (2013) Shyam S. Jayaraman et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Mutational heterogeneity in cancer and the search for new cancer-associated genes
- (2013) Michael S. Lawrence et al. NATURE
- Stem cell quiescence acts as a tumour suppressor in squamous tumours
- (2013) A. C. White et al. NATURE CELL BIOLOGY
- Tracing the cellular origin of cancer
- (2013) Cédric Blanpain NATURE CELL BIOLOGY
- Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma
- (2013) Jessica Okosun et al. NATURE GENETICS
- IntOGen-mutations identifies cancer drivers across tumor types
- (2013) Abel Gonzalez-Perez et al. NATURE METHODS
- Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry
- (2013) Michael J. Kluk et al. PLoS One
- Cancer Genome Landscapes
- (2013) B. Vogelstein et al. SCIENCE
- Strelka: accurate somatic small-variant calling from sequenced tumor–normal sample pairs
- (2012) Christopher T. Saunders et al. BIOINFORMATICS
- Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
- (2012) Sarah Schwitalla et al. CELL
- Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation
- (2012) Naoki Oshimori et al. Cell Stem Cell
- The Harmonies Played by TGF-β in Stem Cell Biology
- (2012) Naoki Oshimori et al. Cell Stem Cell
- VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing
- (2012) D. C. Koboldt et al. GENOME RESEARCH
- Clonal evolution in cancer
- (2012) Mel Greaves et al. NATURE
- Absolute quantification of somatic DNA alterations in human cancer
- (2012) Scott L Carter et al. NATURE BIOTECHNOLOGY
- TGFβ signalling in context
- (2012) Joan Massagué NATURE REVIEWS MOLECULAR CELL BIOLOGY
- RASMutations in Cutaneous Squamous-Cell Carcinomas in Patients Treated with BRAF Inhibitors
- (2012) Fei Su et al. NEW ENGLAND JOURNAL OF MEDICINE
- Predicting the Functional Effect of Amino Acid Substitutions and Indels
- (2012) Yongwook Choi et al. PLoS One
- Skin Tumors Induced by Sorafenib; Paradoxic RAS-RAF Pathway Activation and Oncogenic Mutations of HRAS, TP53, and TGFBR1
- (2011) J. P. Arnault et al. CLINICAL CANCER RESEARCH
- The Complexities of TGF-β Action During Mammary and Squamous Cell Carcinogenesis
- (2011) Erin C. Connolly et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- RASMutations Are Associated With the Development of Cutaneous Squamous Cell Tumors in Patients Treated With RAF Inhibitors
- (2011) Patrick A. Oberholzer et al. JOURNAL OF CLINICAL ONCOLOGY
- Multiple self-healing squamous epithelioma is caused by a disease-specific spectrum of mutations in TGFBR1
- (2011) David R Goudie et al. NATURE GENETICS
- Predicting the functional impact of protein mutations: application to cancer genomics
- (2011) Boris Reva et al. NUCLEIC ACIDS RESEARCH
- Identifying the cellular origin of squamous skin tumors
- (2011) G. Lapouge et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma
- (2011) N. J. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF
- (2010) Sonja J. Heidorn et al. CELL
- Sun-Induced Nonsynonymous p53 Mutations Are Extensively Accumulated and Tolerated in Normal Appearing Human Skin
- (2010) Patrik L. Ståhl et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
- (2010) Poulikos I. Poulikakos et al. NATURE
- RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
- (2010) Georgia Hatzivassiliou et al. NATURE
- A method and server for predicting damaging missense mutations
- (2010) Ivan A Adzhubei et al. NATURE METHODS
- Allele-specific copy number analysis of tumors
- (2010) P. Van Loo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm
- (2009) Prateek Kumar et al. Nature Protocols
- Cooperative Assembly of TGF-β Superfamily Signaling Complexes Is Mediated by Two Disparate Mechanisms and Distinct Modes of Receptor Binding
- (2008) Jay Groppe et al. MOLECULAR CELL
- Crypt stem cells as the cells-of-origin of intestinal cancer
- (2008) Nick Barker et al. NATURE
- Lgr5 marks cycling, yet long-lived, hair follicle stem cells
- (2008) Viljar Jaks et al. NATURE GENETICS
- How the Smads regulate transcription
- (2007) Sarah Ross et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now