Low nanomolar concentrations of Cucurbitacin-I induces G2/M phase arrest and apoptosis by perturbing redox homeostasis in gastric cancer cells in vitro and in vivo
出版年份 2016 全文链接
标题
Low nanomolar concentrations of Cucurbitacin-I induces G2/M phase arrest and apoptosis by perturbing redox homeostasis in gastric cancer cells in vitro and in vivo
作者
关键词
-
出版物
Cell Death & Disease
Volume 7, Issue 2, Pages e2106-e2106
出版商
Springer Nature
发表日期
2016-02-19
DOI
10.1038/cddis.2016.13
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Global cancer statistics, 2012
- (2015) Lindsey A. Torre et al. CA-A CANCER JOURNAL FOR CLINICIANS
- LKB1 Inactivation Elicits a Redox Imbalance to Modulate Non-small Cell Lung Cancer Plasticity and Therapeutic Response
- (2015) Fuming Li et al. CANCER CELL
- Proton pump inhibitor pantoprazole abrogates adriamycin-resistant gastric cancer cell invasiveness via suppression of Akt/GSK-β/β-catenin signaling and epithelial–mesenchymal transition
- (2015) Bin Zhang et al. CANCER LETTERS
- Radioprotective effects of genistein on HL-7702 cells via the inhibition of apoptosis and DNA damage
- (2015) Lihua Song et al. CANCER LETTERS
- Amplification of oxidative stress by a dual stimuli-responsive hybrid drug enhances cancer cell death
- (2015) Joungyoun Noh et al. Nature Communications
- Triptolide induces apoptotic cell death of human cholangiocarcinoma cells through inhibition of myeloid cell leukemia-1
- (2014) Xiwei Ding et al. BMC CANCER
- Silencing of PKCη induces cycle arrest of EBV+ B lymphoma cells by upregulating expression of p38-MAPK/TAp73/GADD45α and increases susceptibility to chemotherapeutic agents
- (2014) Ga Bin Park et al. CANCER LETTERS
- Depletion of Sirtuin 1 (SIRT1) Leads to Epigenetic Modifications of Telomerase (TERT) Gene in Hepatocellular Carcinoma Cells
- (2014) Bin Zhang et al. PLoS One
- Antioxidants Accelerate Lung Cancer Progression in Mice
- (2014) V. I. Sayin et al. Science Translational Medicine
- Cucurbitacin B potently suppresses non-small-cell lung cancer growth: Identification of intracellular thiols as critical targets
- (2013) Hina Kausar et al. CANCER LETTERS
- Capecitabine and cisplatin with or without cetuximab for patients with previously untreated advanced gastric cancer (EXPAND): a randomised, open-label phase 3 trial
- (2013) Florian Lordick et al. LANCET ONCOLOGY
- Gastric cancer—molecular and clinical dimensions
- (2013) Roopma Wadhwa et al. Nature Reviews Clinical Oncology
- Modulation of oxidative stress as an anticancer strategy
- (2013) Chiara Gorrini et al. NATURE REVIEWS DRUG DISCOVERY
- Redox homeostasis: the linchpin in stem cell self-renewal and differentiation
- (2013) Kui Wang et al. Cell Death & Disease
- Cucurbitacin induces autophagy through mitochondrial ROS production which counteracts to limit caspase-dependent apoptosis
- (2012) Tiejun Zhang et al. Autophagy
- DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis
- (2012) Wynand P. Roos et al. CANCER LETTERS
- Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity
- (2012) A Arlt et al. ONCOGENE
- Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in nonsmall cell lung cancer-derived CD133-positive cells
- (2011) Han-Shui Hsu et al. CANCER
- Inhibition of activated Stat3 reverses drug resistance to chemotherapeutic agents in gastric cancer cells
- (2011) Shuling Huang et al. CANCER LETTERS
- Roles of oxidative stress in stomach disorders
- (2011) Hidekazu Suzuki et al. JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION
- Selective killing of cancer cells by a small molecule targeting the stress response to ROS
- (2011) Lakshmi Raj et al. NATURE
- γH2AX: a sensitive molecular marker of DNA damage and repair
- (2010) L-J Mah et al. LEUKEMIA
- Cucurbitacin I Suppressed Stem-Like Property and Enhanced Radiation-Induced Apoptosis in Head and Neck Squamous Carcinoma-Derived CD44+ALDH1+ Cells
- (2010) Y.-W. Chen et al. MOLECULAR CANCER THERAPEUTICS
- Inhibition of Constitutive Activation of STAT3 by Curcurbitacin-I (JSI-124) Sensitized Human B-Leukemia Cells to Apoptosis
- (2010) G. Ishdorj et al. MOLECULAR CANCER THERAPEUTICS
- Therapeutic strategies by modulating oxygen stress in cancer and inflammation
- (2009) Jun Fang et al. ADVANCED DRUG DELIVERY REVIEWS
- Redox-Directed Cancer Therapeutics: Molecular Mechanisms and Opportunities
- (2009) Georg T. Wondrak ANTIOXIDANTS & REDOX SIGNALING
- Cucurbitacin I elicits anoikis sensitization, inhibits cellular invasion and in vivo tumor formation ability of nasopharyngeal carcinoma cells
- (2009) Vivian W.Y. Lui et al. CARCINOGENESIS
- Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin
- (2009) Yoo Ri Kim et al. JOURNAL OF PATHOLOGY
- Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
- (2009) Dunyaporn Trachootham et al. NATURE REVIEWS DRUG DISCOVERY
- Intracellular redox status and oxidative stress: implications for cell proliferation, apoptosis, and carcinogenesis
- (2008) José M. Matés et al. ARCHIVES OF TOXICOLOGY
- Constitutively Activated STAT3 Frequently Coexpresses with Epidermal Growth Factor Receptor in High-Grade Gliomas and Targeting STAT3 Sensitizes Them to Iressa and Alkylators
- (2008) H.-W. Lo et al. CLINICAL CANCER RESEARCH
- Growth arrest and DNA damage-45 alpha (GADD45α)
- (2008) A. Rosemary Siafakas et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started