Article
Food Science & Technology
Ben Niu, Simin Feng, Shuangqing Xuan, Ping Shao
Summary: The study found that using maltodextrin as wall materials can reduce moisture adsorption and caking strength of Tremella fuciformis polysaccharides (TPs) microcapsules powder. The administration of TPs microcapsules powder showed hypoglycemic effects and molecular mechanisms related to regulating the PI3K/Akt pathway, leading to decreased blood glucose levels and improved lipid profiles.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Biochemistry & Molecular Biology
Yaxing Li, Guanping Zhan, Min Tu, Yuhua Wang, Jixuan Cao, Shujing Sun
Summary: In this study, a high-quality chromosome-scale genome of Tremella fuciformis was reported using Pacbio HiFi sequencing combining Hi-C technology. The genome size was 27.38 Mb, organized into 10 chromosomes, with a contig N50 of 2.28 Mb, GC content of 56.51%, BUSCOs completeness of 93.1%, and consensus quality value of 33.7. Additionally, the proteome of T. fuciformis was identified, and 24 genes related to T. fuciformis polysaccharides biosynthesis were discovered in mycelia. This study provides valuable genomic and proteomic information for further biological and genetic studies in T. fuciformis.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Acoustics
Quancen Lee, Xianjing Han, Mingfeng Zheng, Feng Lv, Bin Liu, Feng Zeng
Summary: Different methods were used to degrade Tremella fuciformis polysaccharides (TFP) and prepare low molecular weight polysaccharides of Tremella fuciformis (TFLP) to improve their bioavailability. The TFLP prepared by ultrasonic-assisted H2O2-Vc method showed the highest level of antioxidant activity and stress resistance in C. elegans. TFLP-1, an acid polysaccharide composed mainly of mannose, was found to regulate antioxidant activity and stress resistance in C. elegans through upregulation of various mRNA transcripts.
ULTRASONICS SONOCHEMISTRY
(2023)
Article
Food Science & Technology
Hongjie Yuan, Lin Dong, Zhiyuan Zhang, Yan He, Xia Ma
Summary: This study extracted Tremella fuciformis polysaccharide (TFP) and investigated its physicochemical and biological activities. The results showed that TFP had high purity, moderate molecular weight, and contained various amino acids and carbohydrates. It exhibited excellent antioxidant and water holding capacity, indicating its potential applications in the pharmaceutical, food, and cosmetic industries.
FOOD SCIENCE AND HUMAN WELLNESS
(2022)
Article
Biotechnology & Applied Microbiology
Qian Huang, Yu Liu, Yongfei Deng, Bin Yang, Ruixue Guo, Xiaobao Jin, Lin Zhou
Summary: By optimizing fermentation conditions and purification processes, this study obtained Tremella fuciformis polysaccharide fractions with significant in vitro antioxidant activities, which could serve as active ingredients in functional foods.
FERMENTATION-BASEL
(2022)
Article
Food Science & Technology
Furong Hou, Shuhui Yang, Xiaobin Ma, Zhiqing Gong, Yansheng Wang, Wenliang Wang
Summary: In this study, emulsions stabilized by Tremella fuciformis polysaccharides (TFP) were prepared and evaluated. The TFP emulsions exhibited excellent emulsifying activity and stability, as well as good storage and freeze-thaw stability. The rheological properties of TFP emulsions showed higher viscosity and tendency to form a more stable network structure. Additionally, the O-H bond could be destructed during the emulsion preparation without the formation of new covalent bonds.
Review
Dermatology
Jessica Mineroff, Jared Jagdeo
Summary: Tremella fuciformis, also known as snow mushroom, is an edible mushroom widely used in herbal and Asian medicine and cuisine. Its polysaccharide ingredients have shown positive effects in antioxidation, antitumor, antidiabetic, immunomodulatory, and neuroprotective pathways. However, further clinical research is needed to understand its role in dermatology.
ARCHIVES OF DERMATOLOGICAL RESEARCH
(2023)
Article
Acoustics
Yixuan Li, Yan He, Hua Zhang, Xia Ma
Summary: This study developed a novel method for extracting polysaccharides from Tremella fuciformis spore fermentation broth and compared it with enzymatic and ultrasonic extraction methods. The results showed that the ultrasonic-enzymatic-assisted ethanol precipitation method had the highest extraction rate and the lowest viscosity, and could enhance the activity of polysaccharides.
ULTRASONICS SONOCHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Hongyu Xiao, Hailun Li, Yifan Wen, Dongxu Jiang, Shumin Zhu, Xueling He, Qingping Xiong, Jie Gao, Shaozhen Hou, Song Huang, Lian He, Jian Liang
Summary: TFP shows significant therapeutic effects on DSS-induced UC model by inhibiting inflammation and restoring intestinal barrier and mucus barrier function.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Pharmacology & Pharmacy
Lingna Xie, Kaiye Yang, Yiheng Liang, Zhenyuan Zhu, Zhengqiang Yuan, Zhiyun Du
Summary: Tremella fuciformis polysaccharides (TFPS) have therapeutic effects on atopic dermatitis (AD), with oral administration showing better efficacy than topical application. TFPS treatment increases the proportion of regulatory T cells and modulates the composition of gut microbiota.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Agriculture, Multidisciplinary
Jiaqi Shang, Yang Liu, Jiaxin Kang, Shen Yang, Ritian Jin
Summary: This study demonstrated that TFP-WPI nanoparticles can serve as carriers for CUR, with good stability and sustained release properties.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Food Science & Technology
Lei Gao, Yifei Wang, Fan Zhang, Shiji Li, Jiaqi Zhao, Qing Zhang, Jingrun Ye, Yan Ma, Zhipeng Wang, Wei Chen
Summary: In this study, the problems of poor reproducibilities and large measurement errors in the widely used colorimetric method based on the phenol-sulfuric acid system were addressed through a systematic investigation. The influences of various factors on TFPS determination were intensively studied and optimized, and the accurate quantification of TFPS in the presence of enzyme interference was innovatively realized. This study not only provides a theoretical basis for accurate detection and quantification of TFPS, but also offers insights for standardization and utilization of other types of polysaccharides.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Ding-Tao Wu, Ling-Yan An, Wen Liu, Yi-Chen Hu, Sheng-Peng Wang, Liang Zou
Summary: The polysaccharides from Tremella fuciformis show stability under simulated digestion conditions, but are significantly utilized by intestinal microbiota in human feces after in vitro fermentation, potentially improving intestinal health.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Chemistry, Applied
Fang Yang, Qinling Du, Ting Miao, Xueer Zhang, Wen Xu, Dongying Jia
Summary: This study investigated the mechanism of interaction between Tremella fuciformis polysaccharide (TP) and potato starch (PS). The results showed that TP inhibited starch granule swelling, formed complexes with the starch, and altered the physicochemical properties of the starch. The composite gels exhibited increased rigidity and density, and TP interaction resulted in an increase in the short-range ordered structure of starch.
FOOD HYDROCOLLOIDS
(2022)
Article
Food Science & Technology
Caiyuan Yu, Yan Fang, Weiwei Huang, Peng Lei, Xiaoqi Xu, Dafeng Sun, Lingtian Wu, Hong Xu, Sha Li
Summary: This study investigated the promoting effect of Span 80 on substrate transfer and TFPS production. The results showed that the addition of 0.3% Span 80 significantly increased the yield of TFPS. Span 80 improved the permeability of cell membrane, facilitated TFPS secretion, and enhanced its antioxidant activity.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Food Science & Technology
Wanzi Yao, Xiaoyong Chen, Xiong Li, Shiyuan Chang, Mouming Zhao, Lijun You
Summary: Photoaging is a complex process triggered by UV radiation, causing changes in skin appearance and function, ultimately leading to skin cancer. Non-starch polysaccharides from natural resources are believed to have anti-photoaging effects, but research on this topic is still limited.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Agronomy
Yujiao Yang, Rui Zheng, Pingling Zhang, Jing Wen, Yue Luo, Zhengang Zhao, Lijun You, Chi-Tang Ho
Summary: Sugarcane is rich in polyphenols, including quercetin, apigenin, luteolin, tricin, and p-coumaric acid, which have shown inhibitory effects against MCF-7 breast cancer cells. The combination of luteolin and p-coumaric acid exhibited synergistic effects at all tested concentrations, while luteolin combined with apigenin showed synergistic effects at high inhibition rates. synergistic relation among polyphenols present in sugarcane in inhibition of cancer cell growth.
Article
Chemistry, Applied
Zhengming Xu, Chengtao Wang, Huaifeng Yan, Zhengang Zhao, Lijun You, Chi-Tang Ho
Summary: This study investigated the color intensification of the major anthocyanin in sugarcane by phenolic acids/aldehydes, finding that temperature and concentration affected the color enhancement. Thermodynamic parameters and quantum chemical calculations showed that hydrogen bonds and van der Waals force interactions contributed to color. Pyranoanthocyanins derived from cyanidin-3-O-glucoside and phenolic acids were identified, with electron-donating substituents stabilizing the intermediate carbenium ion forming the final products.
Article
Food Science & Technology
Wanzi Yao, Mengyuan Liu, Xiaoyong Chen, Lijun You, Yongxuan Ma, Kseniya Hileuskaya
Summary: In this study, a degraded purified fraction from Sargassum fusiforme polysaccharides (SFP), called DSFP, was produced by UV/H2O2 degradation and step gradient ethanol precipitation. DSFP showed improved protective effects against intestinal epithelial injury, promoting wound healing and cell migration. It also enhanced intestinal barrier function and attenuated intestinal inflammation.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Chemistry, Applied
Wanzi Yao, Yufeng Gong, Laihao Li, Xiao Hu, Lijun You
Summary: Dietary fibers from rice bran and wheat bran can modulate gut microbiota, enhance intestinal barrier function, regulate the immune system, and play an important role in human health.
Article
Biochemistry & Molecular Biology
Bingxue Lv, Jiahao Ren, Yang Chen, Siyu Guo, Minqian Wu, Lijun You
Summary: In this study, a polysaccharide-based hydrogel microsphere was prepared and its improved properties, including increased springiness, cohesiveness, thermal stability, and enhanced adsorption capacity for crystal violet dye, were demonstrated.
Article
Chemistry, Applied
Xiong Li, Bo Peng, Peter Chi-Keung Cheung, Jiacheng Wang, Xudong Zheng, Lijun You
Summary: Hydrothermal treatment can be used to depolymerize sulfated polysaccharide extracted from Gracilaria chouae to produce low molecular weight polysaccharides. These depolymerized polysaccharides have lower apparent viscosity and modulus, and can promote the growth of beneficial bacteria in the gut while inhibiting the growth of harmful bacteria.
FOOD HYDROCOLLOIDS
(2022)
Article
Biochemistry & Molecular Biology
Yifan Chen, Weixuan Huang, Yang Chen, Minqian Wu, Ruohan Jia, Lijun You
Summary: By degrading LJP with UV/H2O2, hydrogels with different molecular weights were produced for wound dressings with excellent anti-inflammatory activity and swelling property. Low Mw LJP-based hydrogels showed great potential for wound dressing application.
Article
Chemistry, Medicinal
Mengfen Wei, Huamai Qiu, Jie Zhou, Chenghao Yang, Yifan Chen, Lijun You
Summary: Peptides from Pinctada martensii meat have anti-photoaging activities by increasing cell viability and reducing the levels of specific enzymes. Some identified peptides, such as Phe-His (FH), effectively reduce the levels of specific enzymes through molecular docking analysis and show potential as anti-photoaging agents.
Article
Agriculture, Multidisciplinary
Zhengming Xu, Shuang Liu, Huining Lai, Lijun You, Zhengang Zhao
Summary: To improve the liposolubility and bioavailability of phenolic glycosides, highly liposoluble derivatives were efficiently synthesized. These derivatives exhibited high log P values and retained good antioxidant activity, making them potential alternatives to BHT and TBHQ in lipid systems.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Jie Zhou, Mengfen Wei, Lijun You
Summary: In this study, peptides from Pinctada martensii meat were prepared and the structures were identified. The potential antioxidant peptides were synthesized and their activities were verified using HepG2 cells. The results showed that the peptides exhibited antioxidant effects and could be used as candidates in functional foods.
Article
Chemistry, Medicinal
Shiyuan Chang, Xiaoyong Chen, Yifan Chen, Lijun You, Kseniya Hileuskaya
Summary: This study analyzed the structural properties and anti-inflammatory activity of purified fractions derived from UV/H2O2-degraded polysaccharides from Sargassum fusiforme. The results showed that two fractions with different monosaccharide compositions and morphological characteristics were obtained, and PT-0.5 exhibited better anti-inflammatory activity.
Article
Chemistry, Medicinal
Wanzi Yao, Jiayu Yong, Bingxue Lv, Siyu Guo, Lijun You, Peter Chi-Keung Cheung, Viktoryia I. Kulikouskaya
Summary: In this study, UV/H2O2 treatment was used to prepare low-molecular-weight seaweed polysaccharides from Sargassum fusiforme. The treatment effectively degraded the polysaccharides and improved their anti-photoaging activity. UV/H2O2 treatment for 45 minutes showed the best anti-photoaging effect.
Editorial Material
Food Science & Technology
Wanzi Yao, Qiuhong Kong, Lijun You, Saiyi Zhong, Kseniya Hileuskaya
Summary: The intestinal barrier is vital for maintaining gut homeostasis and overall health. Dysfunction of the intestinal barrier is linked to various diseases such as inflammatory bowel disease and colorectal cancer. This review focuses on the physicochemical properties of three main types of brown seaweed polysaccharides (BSP), their absorption and metabolism in the intestine, and their impact on the intestinal barrier. BSP are not directly digested in the upper gastrointestinal tract but can be utilized through fermentation by gut microbiota. They improve intestinal integrity, reduce tight junction dysfunction and intestinal permeability, and promote the production of beneficial metabolites. This review highlights the potential of BSP derived from brown seaweed as a natural and effective approach for preventing and treating intestinal diseases.
Article
Chemistry, Applied
Aliaksandr Kraskouski, Kseniya Hileuskaya, Viktoryia Nikalaichuk, Alena Ladutska, Volha Kabanava, Wanzi Yao, Lijun You
Summary: New chitosan derivatives were obtained by hydrothermal treatment and characterized using various physical and spectroscopic methods. The hydrothermal treatment resulted in a significant decrease in molecular weight and increased antiradical and antimicrobial activities of the derivatives.
CARBOHYDRATE POLYMER TECHNOLOGIES AND APPLICATIONS
(2022)
