Pharmacokinetics of the Antiviral Lectin Griffithsin Administered by Different Routes Indicates Multiple Potential Uses

Antiretrovirals for HIV Exposure Prophylaxis

(2015) G. Nikolopoulos et al.   CURRENT MEDICINAL CHEMISTRY

Monoclonal antibodies: Pharmacokinetics as a basis for new dosage regimens?

(2014) J-R Azanza et al.   JOURNAL OF ONCOLOGY PHARMACY PRACTICE

Activity of and Effect of Subcutaneous Treatment with the Broad-Spectrum Antiviral Lectin Griffithsin in Two Laboratory Rodent Models

(2013) Christopher Barton et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics, Pharmacodynamics and Physiologically-Based Pharmacokinetic Modelling of Monoclonal Antibodies

(2013) Miroslav Dostalek et al.   CLINICAL PHARMACOKINETICS

Griffithsin Protects Mice from Genital Herpes by Preventing Cell-to-Cell Spread

(2013) B. Nixon et al.   JOURNAL OF VIROLOGY

Combinations of Griffithsin with Other Carbohydrate-Binding Agents Demonstrate Superior Activity Against HIV Type 1, HIV Type 2, and Selected Carbohydrate-Binding Agent-Resistant HIV Type 1 Strains

(2012) Geoffrey Férir et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Griffithsin inhibits Japanese encephalitis virus infection in vitro and in vivo

(2012) Hassan Z. A. Ishag et al.   ARCHIVES OF VIROLOGY

Algal Lectins as Potential HIV Microbicide Candidates

(2012) Dana Huskens et al.   Marine Drugs

Griffithsin Has Antiviral Activity against Hepatitis C Virus

(2011) Philip Meuleman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Investigation of Griffithsin's Interactions with Human Cells Confirms Its Outstanding Safety and Efficacy Profile as a Microbicide Candidate

(2011) Joseph Calvin Kouokam et al.   PLoS One

The Glycan Shield of HIV Is Predominantly Oligomannose Independently of Production System or Viral Clade

(2011) Camille Bonomelli et al.   PLoS One

Synergistic activity profile of griffithsin in combination with tenofovir, maraviroc and enfuvirtide against HIV-1 clade C

(2011) Geoffrey Férir et al.   VIROLOGY

The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4+ cells

(2011) Kabamba B. Alexandre et al.   VIROLOGY

A Lectin Isolated from Bananas Is a Potent Inhibitor of HIV Replication

(2010) Michael D. Swanson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel L-ficolin/Mannose-binding Lectin Chimeric Molecule with Enhanced Activity against Ebola Virus

(2010) Ian C. Michelow et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-Dose Mannose-Binding Lectin Therapy for Ebola Virus Infection

(2010) Ian C. Michelow et al.   JOURNAL OF INFECTIOUS DISEASES

Envelope glycans of immunodeficiency virions are almost entirely oligomannose antigens

(2010) K. J. Doores et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity

(2010) Tinoush Moulaei et al.   STRUCTURE

Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin

(2010) Kabamba B. Alexandre et al.   VIROLOGY

Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

(2009) B. R. O'Keefe et al.   JOURNAL OF VIROLOGY

Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

(2009) B. R. O'Keefe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA