Bisphenol A-Induced Ovotoxicity Involves DNA Damage Induction to Which the Ovary Mounts a Protective Response Indicated by Increased Expression of Proteins Involved in DNA Repair and Xenobiotic Biotransformation

Impact of Obesity on Ovotoxicity Induced by 7,12-dimethylbenz[a]anthracene in Mice1

(2014) Jackson Nteeba et al.   BIOLOGY OF REPRODUCTION

Xenobiotic effects in the ovary: temporary versus permanent infertility

(2014) Patricia B Hoyer et al.   Expert Opinion on Drug Metabolism & Toxicology

Acute 7,12-dimethylbenz[a]anthracene exposure causes differential concentration-dependent follicle depletion and gene expression in neonatal rat ovaries

(2014) Jill A. Madden et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Exposure to bisphenol A at physiological concentrations observed in Chinese children promotes primordial follicle growth through the PI3K/Akt pathway in an ovarian culture system

(2014) Qian Zhao et al.   TOXICOLOGY IN VITRO

Melatonin ameliorates bisphenol A-induced DNA damage in the germ cells of adult male rats

(2013) Hong-Juan Wu et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Plastics Derived Endocrine Disruptors (BPA, DEHP and DBP) Induce Epigenetic Transgenerational Inheritance of Obesity, Reproductive Disease and Sperm Epimutations

(2013) Mohan Manikkam et al.   PLoS One

7,12-Dimethylbenz[a]anthracene exposure induces the DNA repair response in neonatal rat ovaries

(2013) Shanthi Ganesan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Bisphenol A Inhibits Follicle Growth and Induces Atresia in Cultured Mouse Antral Follicles Independently of the Genomic Estrogenic Pathway1

(2012) Jackye Peretz et al.   BIOLOGY OF REPRODUCTION

Bisphenol A inhibits proliferation and induces apoptosis in micromass cultures of rat embryonic midbrain cells through the JNK, CREB and p53 signaling pathways

(2012) Ran Liu et al.   FOOD AND CHEMICAL TOXICOLOGY

Identification of DNA-Dependent Protein Kinase Catalytic Subunit (DNA-PKcs) as a Novel Target of Bisphenol A

(2012) Yuki Ito et al.   PLoS One

Protective role for ovarian glutathione S-transferase isoform pi during 7,12-dimethylbenz[a]anthracene-induced ovotoxicity

(2012) Poulomi Bhattacharya et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Glutathione S-transferase class mu regulation of apoptosis signal-regulating kinase 1 protein during VCD-induced ovotoxicity in neonatal rat ovaries

(2012) Poulomi Bhattacharya et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Roles of Reactive Oxygen Species and Antioxidants in Ovarian Toxicity1

(2011) Patrick J. Devine et al.   BIOLOGY OF REPRODUCTION

Ovarian metabolism of xenobiotics

(2011) Poulomi Bhattacharya et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Fetal exposure to bisphenol A affects the primordial follicle formation by inhibiting the meiotic progression of oocytes

(2011) Han-Qiong Zhang et al.   MOLECULAR BIOLOGY REPORTS

Gene expression is altered after bisphenol A exposure in human fetal oocytes in vitro

(2011) M. A. Brieno-Enriquez et al.   MOLECULAR HUMAN REPRODUCTION

Antiproliferative and proapoptotic effects of bisphenol A on human trophoblastic JEG-3 cells

(2011) Lucie Morice et al.   REPRODUCTIVE TOXICOLOGY

Ovarian expressed microsomal epoxide hydrolase: Role in detoxification of 4-vinylcyclohexene diepoxide and regulation by phosphatidylinositol-3 kinase signaling

(2011) Poulomi Bhattacharya et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene

(2010) Lisa Becks et al.   BMC CANCER

DNA damage signaling in response to double-strand breaks during mitosis

(2010) Simona Giunta et al.   JOURNAL OF CELL BIOLOGY

Bisphenol A impairs the double-strand break repair machinery in the germline and causes chromosome abnormalities

(2010) P. Allard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neonatal exposure to bisphenol A reduces the pool of primordial follicles in the rat ovary

(2010) Horacio A. Rodríguez et al.   REPRODUCTIVE TOXICOLOGY

Semen quality and sperm DNA damage in relation to urinary bisphenol A among men from an infertility clinic☆☆☆

(2010) John D. Meeker et al.   REPRODUCTIVE TOXICOLOGY

Bisphenol A Impairs Follicle Growth, Inhibits Steroidogenesis, and Downregulates Rate-Limiting Enzymes in the Estradiol Biosynthesis Pathway

(2010) Jackye Peretz et al.   TOXICOLOGICAL SCIENCES

Dual protective role for Glutathione S-transferase class pi against VCD-induced ovotoxicity in the rat ovary☆

(2010) Aileen F. Keating et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Subfertility Caused by Altered Follicular Development and Oocyte Growth in Female Mice Lacking PKBalpha/Akt11

(2009) Caitlin Brown et al.   BIOLOGY OF REPRODUCTION

Mechanism of elimination of phosphorylated histone H2AX from chromatin after repair of DNA double-strand breaks

(2009) M.P. Svetlova et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Formation of adducts by bisphenol A, an endocrine disruptor, in DNA in vitro and in liver and mammary tissue of mice

(2009) Alberto Izzotti et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Effect of phosphatidylinositol-3 kinase inhibition on ovotoxicity caused by 4-vinylcyclohexene diepoxide and 7, 12-dimethylbenz[a]anthracene in neonatal rat ovaries

(2009) Aileen F. Keating et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Characterization of the glutathione S-transferase-Mu (GSTM) gene sequence and its expression in the hermaphroditic fish, Kryptolebias marmoratus as a function of development, gender type and chemical exposure

(2008) In Tag Yu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Foxo3 is a PI3K-dependent molecular switch controlling the initiation of oocyte growth

(2008) George B. John et al.   DEVELOPMENTAL BIOLOGY

Expression of ovarian microsomal epoxide hydrolase and glutathione S-transferase during onset of VCD-induced ovotoxicity in B6C3F1 mice

(2008) Aileen F. Keating et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Evaluation of ovotoxicity induced by 7, 12-dimethylbenz[a]anthracene and its 3,4-diol metabolite utilizing a rat in vitro ovarian culture system

(2008) Yoshiyuki Igawa et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY