DNA Nanotechnology for Precise Control over Drug Delivery and Gene Therapy

Biomimetic DNA nanoballs for oligonucleotide delivery

(2015) Mi-Gyeong Kim et al.   BIOMATERIALS

DNA nanotubes as intracellular delivery vehicles in vivo

(2015) Sabine Sellner et al.   BIOMATERIALS

Optimal DNA Templates for Rolling Circle Amplification Revealed by In Vitro Selection

(2015) Yu Mao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enzymatic Synthesis of Periodic DNA Nanoribbons for Intracellular pH Sensing and Gene Silencing

(2015) Gang Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembly of DNA Nanohydrogels with Controllable Size and Stimuli-Responsive Property for Targeted Gene Regulation Therapy

(2015) Juan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Programmable motion of DNA origami mechanisms

(2015) Alexander E. Marras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclease-resistant synthetic drug-DNA adducts: programmable drug-DNA conjugation for targeted anticancer drug delivery

(2015) Guizhi Zhu et al.   NPG Asia Materials

A Controllable Aptamer-Based Self-Assembled DNA Dendrimer for High Affinity Targeting, Bioimaging and Drug Delivery

(2015) Huimin Zhang et al.   Scientific Reports

DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy

(2014) Qian Zhang et al.   ACS Nano

Multiresponsive Rolling Circle Amplification for DNA Logic Gates Mediated by Endonuclease

(2014) Weidong Xu et al.   ANALYTICAL CHEMISTRY

Intercalation of antitumor drug doxorubicin and its analogue by DNA duplex: Structural features and biological implications

(2014) Daniel Agudelo et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Cocoon-Like Self-Degradable DNA Nanoclew for Anticancer Drug Delivery

(2014) Wujin Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Virus-Encapsulated DNA Origami Nanostructures for Cellular Delivery

(2014) Joona Mikkilä et al.   NANO LETTERS

Polyhedra Self-Assembled from DNA Tripods and Characterized with 3D DNA-PAINT

(2014) R. Iinuma et al.   SCIENCE

Controlled release of an anti-cancer drug from DNA structured nano-films

(2014) Younghyun Cho et al.   Scientific Reports

Drug delivery by a self-assembled DNA tetrahedron for overcoming drug resistance in breast cancer cells

(2013) Kyoung-Ran Kim et al.   CHEMICAL COMMUNICATIONS

Building a Multifunctional Aptamer-Based DNA Nanoassembly for Targeted Cancer Therapy

(2013) Cuichen Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stable RNA interference rules for silencing

(2013) Christof Fellmann et al.   NATURE CELL BIOLOGY

Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics

(2013) G. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma

(2013) S. A. Jensen et al.   Science Translational Medicine

Rolling Circle Amplification-Based DNA Origami Nanostructrures for Intracellular Delivery of Immunostimulatory Drugs

(2013) Xiangyuan Ouyang et al.   Small

DNA Origami Delivery System for Cancer Therapy with Tunable Release Properties

(2012) Yong-Xing Zhao et al.   ACS Nano

Functionalized DNA Nanostructures

(2012) Ofer I. Wilner et al.   CHEMICAL REVIEWS

DNA Origami as a Carrier for Circumvention of Drug Resistance

(2012) Qiao Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rolling Circle Amplification-Templated DNA Nanotubes Show Increased Stability and Cell Penetration Ability

(2012) Graham D. Hamblin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembled RNA interference microsponges for efficient siRNA delivery

(2012) Jong Bum Lee et al.   NATURE MATERIALS

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Rapid Folding of DNA into Nanoscale Shapes at Constant Temperature

(2012) J.-P. J. Sobczak et al.   SCIENCE

Three-Dimensional Structures Self-Assembled from DNA Bricks

(2012) Y. Ke et al.   SCIENCE

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

Two design strategies for enhancement of multilayer–DNA-origami folding: underwinding for specific intercalator rescue and staple-break positioning

(2012) Yonggang Ke et al.   Chemical Science

Aptamer-Conjugated DNA Icosahedral Nanoparticles As a Carrier of Doxorubicin for Cancer Therapy

(2011) Microsugar Chang et al.   ACS Nano

Self-Assembled Multivalent DNA Nanostructures for Noninvasive Intracellular Delivery of Immunostimulatory CpG Oligonucleotides

(2011) Jiang Li et al.   ACS Nano

DNA origami: a quantum leap for self-assembly of complex structures

(2011) Thomas Tørring et al.   CHEMICAL SOCIETY REVIEWS

Uptake mechanisms of non-viral gene delivery

(2011) Shengnan Xiang et al.   JOURNAL OF CONTROLLED RELEASE

Gene Silencing by siRNA Microhydrogels via Polymeric Nanoscale Condensation

(2011) Cheol Am Hong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform

(2011) C.-M. J. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An autonomous DNA nanomachine maps spatiotemporal pH changes in a multicellular living organism

(2011) Sunaina Surana et al.   Nature Communications

Engineering RNA for Targeted siRNA Delivery and Medical Application

(2010) Peixuan Guo et al.   ADVANCED DRUG DELIVERY REVIEWS

Bioluminescent imaging of reporter gene expression in the lungs of wildtype and model mice following the administration of PEG-stabilized DNA nanoparticles

(2010) Assem G. Ziady et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Nucleolin-Mediated Cellular Trafficking of DNA Nanoparticle Is Lipid Raft and Microtubule Dependent and Can Be Modulated by Glucocorticoid

(2010) Xuguang Chen et al.   MOLECULAR THERAPY

Impact of Nanotechnology on Drug Delivery

(2009) Omid C. Farokhzad et al.   ACS Nano

Icosahedral DNA Nanocapsules by Modular Assembly

(2009) Dhiraj Bhatia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Long-term Transgene Expression in the Central Nervous System Using DNA Nanoparticles

(2009) David M Yurek et al.   MOLECULAR THERAPY

Self-assembly of DNA into nanoscale three-dimensional shapes

(2009) Shawn M. Douglas et al.   NATURE

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

A DNA nanomachine that maps spatial and temporal pH changes inside living cells

(2009) Souvik Modi et al.   Nature Nanotechnology

Self-assembled cationic peptide nanoparticles as an efficient antimicrobial agent

(2009) Lihong Liu et al.   Nature Nanotechnology

DNA Origami Design of Dolphin-Shaped Structures with Flexible Tails

(2008) Ebbe S. Andersen et al.   ACS Nano

DNA Block Copolymer Micelles – A Combinatorial Tool for Cancer Nanotechnology

(2008) F. E. Alemdaroglu et al.   ADVANCED MATERIALS

Cellular Uptake and Intracellular Pathways of PLL-g-PEG-DNA Nanoparticles

(2008) Tessa Lühmann et al.   BIOCONJUGATE CHEMISTRY

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS

Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra

(2008) Yu He et al.   NATURE

Conformational flexibility facilitates self-assembly of complex DNA nanostructures

(2008) C. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo cloning of artificial DNA nanostructures

(2008) C. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA