Proximity biotinylation provides insight into the molecular composition of focal adhesions at the nanometer scale

Plasticity of PI4KIII  interactions at the plasma membrane

(2015) J. Chung et al.   EMBO REPORTS

Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly

(2015) Edward R. Horton et al.   NATURE CELL BIOLOGY

Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions

(2015) Lindsay B. Case et al.   NATURE CELL BIOLOGY

Talin determines the nanoscale architecture of focal adhesions

(2015) Jaron Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic Analysis of Proteins Surrounding Occludin and Claudin-4 Reveals Their Proximity to Signaling and Trafficking Networks

(2015) Karin Fredriksson et al.   PLoS One

SnapShot: Talin and the Modular Nature of the Integrin Adhesome

(2014) Feng Ye et al.   CELL

Talin Dependent Mechanosensitivity of Cell Focal Adhesions

(2014) Jie Yan et al.   Cellular and Molecular Bioengineering

Integrin-Associated Complexes Form Hierarchically with Variable Stoichiometry in Nascent Adhesions

(2014) Alexia I. Bachir et al.   CURRENT BIOLOGY

Proximity Interactions among Centrosome Components Identify Regulators of Centriole Duplication

(2014) Elif Nur Firat-Karalar et al.   CURRENT BIOLOGY

Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation

(2014) C. Huet-Calderwood et al.   JOURNAL OF CELL SCIENCE

Liprin- 1, ERC1 and LL5 define polarized and dynamic structures that are implicated in cell migration

(2014) V. Astro et al.   JOURNAL OF CELL SCIENCE

RhoA activation by CNFy restores cell-cell adhesion in kindlin-2-deficient keratinocytes

(2014) Yinghong He et al.   JOURNAL OF PATHOLOGY

The integrin adhesome: from genes and proteins to human disease

(2014) Sabina E. Winograd-Katz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Kank Is an EB1 Interacting Protein that Localises to Muscle-Tendon Attachment Sites in Drosophila

(2014) Sara M. R. Clohisey et al.   PLoS One

Probing nuclear pore complex architecture with proximity-dependent biotinylation

(2014) D. I. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular physiology of the tensin brotherhood of integrin adaptor proteins

(2014) Donald T. Haynie   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

(2014) Z. Guo et al.   Science Signaling

Symmetric exchange of multi-protein building blocks between stationary focal adhesions and the cytosol

(2014) Jan-Erik Hoffmann et al.   eLife

A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties

(2013) James M. Murphy et al.   BIOCHEMICAL JOURNAL

The RasGAP Gene, RASAL2, Is a Tumor and Metastasis Suppressor

(2013) Sara Koenig McLaughlin et al.   CANCER CELL

The GTPase-Activating Protein RN-tre Controls Focal Adhesion Turnover and Cell Migration

(2013) Andrea Palamidessi et al.   CURRENT BIOLOGY

Mechanosensitivity and compositional dynamics of cell–matrix adhesions

(2013) Herbert B Schiller et al.   EMBO REPORTS

Nck enables directional cell migration through the coordination of polarized membrane protrusion with adhesion dynamics

(2013) S. P. Chaki et al.   JOURNAL OF CELL SCIENCE

The role of integrin-linked kinase in the molecular architecture of focal adhesions

(2013) N. Elad et al.   JOURNAL OF CELL SCIENCE

αE-catenin actin-binding domain alters actin filament conformation and regulates binding of nucleation and disassembly factors

(2013) Scott D. Hansen et al.   MOLECULAR BIOLOGY OF THE CELL

The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

(2013) Dattatreya Mellacheruvu et al.   NATURE METHODS

Talins and kindlins: partners in integrin-mediated adhesion

(2013) David A. Calderwood et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The MIntAct project—IntAct as a common curation platform for 11 molecular interaction databases

(2013) Sandra Orchard et al.   NUCLEIC ACIDS RESEARCH

EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation

(2013) E. A. Bard-Chapeau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution Structure of the First Sam Domain of Odin and Binding Studies with the EphA2 Receptor

(2012) Flavia Anna Mercurio et al.   BIOCHEMISTRY

Cell Adhesion: A FERM Grasp of the Tail Sorts Out Integrins

(2012) Nina N. Brahme et al.   CURRENT BIOLOGY

Opening the floodgates: proteomics and the integrin adhesome

(2012) Tamar Geiger et al.   CURRENT OPINION IN CELL BIOLOGY

Spatial Coordination of Kindlin-2 with Talin Head Domain in Interaction with Integrin β Cytoplasmic Tails

(2012) Kamila Bledzka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity

(2012) Fubito Nakatsu et al.   JOURNAL OF CELL BIOLOGY

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells

(2012) Kyle J. Roux et al.   JOURNAL OF CELL BIOLOGY

CD98 at the crossroads of adaptive immunity and cancer

(2012) J. M. Cantor et al.   JOURNAL OF CELL SCIENCE

Comparison and applications of label-free absolute proteome quantification methods on Escherichia coli

(2012) L. Arike et al.   Journal of Proteomics

The Lipid Raft-Associated Protein CD98 Is Required for Vaccinia Virus Endocytosis

(2012) N. Schroeder et al.   JOURNAL OF VIROLOGY

Comparative Proteomic Analysis of Eleven Common Cell Lines Reveals Ubiquitous but Varying Expression of Most Proteins

(2012) Tamar Geiger et al.   MOLECULAR & CELLULAR PROTEOMICS

STRING v9.1: protein-protein interaction networks, with increased coverage and integration

(2012) Andrea Franceschini et al.   NUCLEIC ACIDS RESEARCH

Kindlin-1 and -2 Have Overlapping Functions in Epithelial Cells

(2011) Yinghong He et al.   AMERICAN JOURNAL OF PATHOLOGY

The integrin coactivator Kindlin-2 plays a critical role in angiogenesis in mice and zebrafish

(2011) E. Pluskota et al.   BLOOD

Super-Resolution Microscopy: A New Dimension in Focal Adhesions

(2011) Martin Alexander Schwartz   CURRENT BIOLOGY

Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins

(2011) Herbert B Schiller et al.   EMBO REPORTS

Protein 4.1R regulates cell adhesion, spreading, migration and motility of mouse keratinocytes by modulating surface expression of  1 integrin

(2011) L. Chen et al.   JOURNAL OF CELL SCIENCE

Actomyosin-generated tension controls the molecular kinetics of focal adhesions

(2011) H. Wolfenson et al.   JOURNAL OF CELL SCIENCE

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

(2011) Jean-Cheng Kuo et al.   NATURE CELL BIOLOGY

Basement membrane sliding and targeted adhesion remodels tissue boundaries during uterine–vulval attachment in Caenorhabditis elegans

(2011) Shinji Ihara et al.   NATURE CELL BIOLOGY

Mammalian Pragmin regulates Src family kinases via the Glu-Pro-Ile-Tyr-Ala (EPIYA) motif that is exploited by bacterial effectors

(2011) F. Safari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic Analysis of Integrin Adhesion Complexes

(2011) A. Byron et al.   Science Signaling

The tail of integrin activation

(2011) Nicholas J. Anthis et al.   TRENDS IN BIOCHEMICAL SCIENCES

Productive tension: force-sensing and homeostasis of cell–cell junctions

(2011) Guillermo A. Gomez et al.   TRENDS IN CELL BIOLOGY

Molecular Architecture and Function of Matrix Adhesions

(2011) B. Geiger et al.   Cold Spring Harbor Perspectives in Biology

Liprin-α1 affects the distribution of low-affinity β1 integrins and stabilizes their permanence at the cell surface

(2010) Claudia Asperti et al.   EXPERIMENTAL CELL RESEARCH

The interactome of a PTB domain-containing adapter protein, Odin, revealed by SILAC

(2010) Jun Zhong et al.   Journal of Proteomics

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography

(2010) Israel Patla et al.   NATURE CELL BIOLOGY

Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression

(2010) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell adhesion and EGFR activation regulate EphA2 expression in cancer

(2009) Alice Bjerregaard Larsen et al.   CELLULAR SIGNALLING

Multiparametric analysis of focal adhesion formation by RNAi-mediated gene knockdown

(2009) Sabina E. Winograd-Katz et al.   JOURNAL OF CELL BIOLOGY

Molecular dissection of the ILK-PINCH-parvin triad reveals a fundamental role for the ILK kinase domain in the late stages of focal-adhesion maturation

(2009) F. Stanchi et al.   JOURNAL OF CELL SCIENCE

Proteomic Analysis of Integrin-Associated Complexes Identifies RCC2 as a Dual Regulator of Rac1 and Arf6

(2009) J. D. Humphries et al.   Science Signaling

The heel and toe of the cell's foot: A multifaceted approach for understanding the structure and dynamics of focal adhesions

(2009) Haguy Wolfenson et al.   CELL MOTILITY AND THE CYTOSKELETON

Paxillin nuclear-cytoplasmic localization is regulated by phosphorylation of the LD4motif: evidence that nuclear paxillin promotes cell proliferation

(2008) Jing-Ming Dong et al.   BIOCHEMICAL JOURNAL

Cell cycle regulated phosphorylation of LIMD1 in cell lines and expression in human breast cancers

(2008) Christopher Jack Huggins et al.   CANCER LETTERS

The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction

(2008) Vladimir Pena et al.   EMBO REPORTS

Kindlin-2 controls bidirectional signaling of integrins

(2008) E. Montanez et al.   GENES & DEVELOPMENT

RIAM Activates Integrins by Linking Talin to Ras GTPase Membrane-targeting Sequences

(2008) Ho-Sup Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paxillin comes of age

(2008) N. O. Deakin et al.   JOURNAL OF CELL SCIENCE

Rolling blackout is required for bulk endocytosis in non-neuronal cells and neuronal synapses

(2008) N. Vijayakrishnan et al.   JOURNAL OF CELL SCIENCE

Structures of Dimeric GIT1 and Trimeric β-PIX and Implications for GIT–PIX Complex Assembly

(2008) Oliver Schlenker et al.   JOURNAL OF MOLECULAR BIOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Precision proteomics: The case for high resolution and high mass accuracy

(2008) M. Mann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Analysis of the Interactions Between Paxillin LD Motifs and α-Parvin

(2008) Sonja Lorenz et al.   STRUCTURE

Promiscuous protein biotinylation by Escherichia coli biotin protein ligase

(2004) Eunjoo Choi-Rhee et al.   PROTEIN SCIENCE