Enantioselective cyanation of benzylic C–H bonds via copper-catalyzed radical relay

Asymmetric copper-catalyzed C-N cross-couplings induced by visible light

(2016) Q. M. Kainz et al.   SCIENCE

Functionalization of C(sp3)-H bonds using a transient directing group

(2016) F.-L. Zhang et al.   SCIENCE

Manganese Catalyzed C–H Halogenation

(2015) Wei Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Methods and Mechanisms for Cross-Electrophile Coupling of Csp2 Halides with Alkyl Electrophiles

(2015) Daniel J. Weix   ACCOUNTS OF CHEMICAL RESEARCH

Enantioselective Nickel-Catalyzed Hydrocyanation using Chiral Phosphine-Phosphite Ligands: Recent Improvements and Insights

(2015) Anna Falk et al.   ADVANCED SYNTHESIS & CATALYSIS

Direct Coupling of Arylacetonitriles and Primary Alcohols to α-Alkylated Arylacetamides with Complete Atom Economy Catalyzed by a Rhodium Complex-Triphenylphosphine- Potassium Hydroxide System

(2015) Feng Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic C–H Imidation of Aromatic Cores of Functional Molecules: Ligand-Accelerated Cu Catalysis and Application to Materials- and Biology-Oriented Aromatics

(2015) Takahiro Kawakami et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Rhodium-Catalyzed Allylic Substitution with a Nitrile Anion: Construction of Acyclic Quaternary Carbon Stereogenic Centers

(2015) Ben W. H. Turnbull et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoinduced, Copper-Catalyzed Carbon–Carbon Bond Formation with Alkyl Electrophiles: Cyanation of Unactivated Secondary Alkyl Chlorides at Room Temperature

(2015) Tanvi S. Ratani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Cross-Coupling of Photoredox-Generated Radicals: Uncovering a General Manifold for Stereoconvergence in Nickel-Catalyzed Cross-Couplings

(2015) Osvaldo Gutierrez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metal-catalysed azidation of tertiary C–H bonds suitable for late-stage functionalization

(2015) Ankit Sharma et al.   NATURE

Palladium-Catalyzed Carbonylations of Aryl Bromides using Paraformaldehyde: Synthesis of Aldehydes and Esters

(2014) Kishore Natte et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-catalyzed intermolecular cyanotrifluoromethylation of alkenes: Convenient synthesis of CF3-containing alkyl nitriles

(2014) Zhaoli Liang et al.   JOURNAL OF FLUORINE CHEMISTRY

Copper-Catalyzed Intermolecular Trifluoromethylarylation of Alkenes: Mutual Activation of Arylboronic Acid and CF3+ Reagent

(2014) Fei Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Negishi Arylations of Propargylic Bromides: A Mechanistic Investigation

(2014) Nathan D. Schley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-electron transmetalation in organoboron cross-coupling by photoredox/nickel dual catalysis

(2014) J. C. Tellis et al.   SCIENCE

Merging photoredox with nickel catalysis: Coupling of  -carboxyl sp3-carbons with aryl halides

(2014) Z. Zuo et al.   SCIENCE

Efficient assembly of α-aryl and α-vinyl nitriles via iron-catalyzed ether bond activation

(2014) Xiaohui Fan et al.   TETRAHEDRON LETTERS

Copper-Catalyzed Intermolecular Aminocyanation and Diamination of Alkenes

(2013) Hongwei Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photoinduced Direct Cyanation of C(sp3)-H Bonds

(2013) Masayuki Inoue et al.   SYNTHESIS-STUTTGART

Nickel-catalyzed decyanation of inert carbon–cyano bonds

(2012) Tuhin Patra et al.   CHEMICAL COMMUNICATIONS

First Intramolecular Alkylation of Nitriles with Primary and Secondary Alcohols Catalyzed by Iridium Complexes

(2012) Bruno Anxionnat et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Reaction of CuI with Dialkyl Peroxides: CuII-Alkoxides, Alkoxy Radicals, and Catalytic C–H Etherification

(2012) Raymond T. Gephart et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Regioselective Copper-Catalyzed Benzylic CH Amination by N-Fluorobenzenesulfonimide

(2011) Zhikun Ni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of α-Aryl Nitriles through Palladium-Catalyzed Decarboxylative Coupling of Cyanoacetate Salts with Aryl Halides and Triflates

(2011) Rui Shang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Aerobic Oxidative CH Functionalizations: Trends and Mechanistic Insights

(2011) Alison E. Wendlandt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fe-catalysed oxidative C–H functionalization/C–S bond formation

(2011) Haibo Wang et al.   CHEMICAL COMMUNICATIONS

Biocatalytic strategies for the asymmetric synthesis of profens – recent trends and developments

(2011) Robert Kourist et al.   GREEN CHEMISTRY

Intramolecular Oxidative C−N Bond Formation for the Synthesis of Carbazoles: Comparison of Reactivity between the Copper-Catalyzed and Metal-Free Conditions

(2011) Seung Hwan Cho et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel α-arylnitriles synthesis via Ni-catalyzed cross-coupling of α-bromonitriles with arylboronic acids under mild conditions

(2011) Yingying Yang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enzymatic functionalization of carbon–hydrogen bonds

(2010) Jared C. Lewis et al.   CHEMICAL SOCIETY REVIEWS

Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: SAR and Structural Characterization

(2010) Daniel K. Whelligan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore

(2010) Fraser F. Fleming et al.   JOURNAL OF MEDICINAL CHEMISTRY

Hydrocarbon Hydroxylation by Cytochrome P450 Enzymes

(2009) Paul R. Ortiz de Montellano   CHEMICAL REVIEWS

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

Universal Solvation Model Based on Solute Electron Density and on a Continuum Model of the Solvent Defined by the Bulk Dielectric Constant and Atomic Surface Tensions

(2009) Aleksandr V. Marenich et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Mechanistic considerations of halogenating enzymes

(2009) Alison Butler et al.   NATURE

Low pressure vinylation of aryl and vinyl halides via Heck–Mizoroki reactions using ethylene

(2009) Craig R. Smith et al.   TETRAHEDRON

Synthesis of 2-Arylbenzoxazoles by Copper-Catalyzed Intramolecular Oxidative CO Coupling of Benzanilides

(2008) Satoshi Ueda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Assembled Bidentate Ligands for the Nickel-Catalyzed Hydrocyanation of Alkenes

(2008) Michiel de Greef et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion

(2008) Huw M. L. Davies et al.   NATURE