Expanding the application potential of DNA aptamers by their functionalization

Systematic selection of modified aptamer pairs for diagnostic sandwich assays

(2016) Urs A. Ochsner et al.   BIOTECHNIQUES

Particle Display: A Quantitative Screening Method for Generating High-Affinity Aptamers

(2014) Jinpeng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Emerging techniques employed in aptamer-based diagnostic tests

(2014) Wataru Yoshida et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Current Progress of Aptamer-Based Molecular Imaging

(2014) A. Z. Wang et al.   JOURNAL OF NUCLEAR MEDICINE

Optimization of SELEX: Comparison of different methods for monitoring the progress of in vitro selection of aptamers

(2014) Nina Mencin et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Proteomics Analysis of Cancer Exosomes Using a Novel Modified Aptamer-based Array (SOMAscanTM) Platform

(2014) Jason Webber et al.   MOLECULAR & CELLULAR PROTEOMICS

Defining NELF-E RNA Binding in HIV-1 and Promoter-Proximal Pause Regions

(2014) John M. Pagano et al.   PLoS Genetics

New Strategies for Evaluation and Analysis of SELEX Experiments

(2014) Rico Beier et al.   Biomed Research International

Conversion Strategy Using an Expanded Genetic Alphabet to Assay Nucleic Acids

(2013) Zunyi Yang et al.   ANALYTICAL CHEMISTRY

Multiplexed Microcolumn-Based Process for Efficient Selection of RNA Aptamers

(2013) David R. Latulippe et al.   ANALYTICAL CHEMISTRY

A cross-contamination-free SELEX platform for a multi-target selection strategy

(2013) SangWook Lee et al.   BioChip Journal

An ultra-sensitive detection of a whole virus using dual aptamers developed by immobilization-free screening

(2013) Jee-Woong Park et al.   BIOSENSORS & BIOELECTRONICS

A Mixed Mirror-image DNA/RNA Aptamer Inhibits Glucagon and Acutely Improves Glucose Tolerance in Models of Type 1 and Type 2 Diabetes

(2013) Axel Vater et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleic acid aptamers as high affinity ligands in biotechnology and biosensorics

(2013) Tina Šmuc et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Generation of high-affinity DNA aptamers using an expanded genetic alphabet

(2013) Michiko Kimoto et al.   NATURE BIOTECHNOLOGY

RAPID-SELEX for RNA Aptamers

(2013) Kylan Szeto et al.   PLoS One

In vitro selection with artificial expanded genetic information systems

(2013) K. Sefah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-stranded DNA (ssDNA) production in DNA aptamer generation

(2012) Citartan Marimuthu et al.   ANALYST

Comparison of different methods for generation of single-stranded DNA for SELEX processes

(2012) M. Svobodová et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

DNase-Mediated Single-Cycle Selection of Aptamers for Proteins Blotted on a Membrane

(2012) Yanming Liu et al.   ANALYTICAL CHEMISTRY

Selection Strategy to Generate Aptamer Pairs that Bind to Distinct Sites on Protein Targets

(2012) Qiang Gong et al.   ANALYTICAL CHEMISTRY

A simple and effective colorimetric technique for the detection of boronic acids and their derivatives

(2012) Katherine Lawrence et al.   Analytical Methods

HEXIM1-binding elements on mRNAs identified through transcriptomic SELEX and computational screening

(2012) Yuki Fujimoto et al.   BIOCHIMIE

One round of SELEX for the generation of DNA aptamers directed against KLK6

(2012) Steve Arnold et al.   BIOLOGICAL CHEMISTRY

Aptamer selection by high-throughput sequencing and informatic analysis

(2012) Shawn Hoon et al.   BIOTECHNIQUES

Nucleic acid aptamers: an emerging frontier in cancer therapy

(2012) Guizhi Zhu et al.   CHEMICAL COMMUNICATIONS

Convergent Evolution of Adenosine Aptamers Spanning Bacterial, Human, and Random Sequences Revealed by Structure-Based Bioinformatics and Genomic SELEX

(2012) Michael M.K. Vu et al.   CHEMISTRY & BIOLOGY

Selection of bovine catalase aptamers using non-SELEX

(2012) Jon Ashley et al.   ELECTROPHORESIS

Therapeutic RNA aptamers in clinical trials

(2012) Padma Sundaram et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Isolation and Optimization of Murine IL-10 Receptor Blocking Oligonucleotide Aptamers Using High-throughput Sequencing

(2012) Alexey Berezhnoy et al.   MOLECULAR THERAPY

Aptamers as potential tools for super-resolution microscopy

(2012) Felipe Opazo et al.   NATURE METHODS

Selection is more intelligent than design: improving the affinity of a bivalent ligand through directed evolution

(2012) Kareem M. Ahmad et al.   NUCLEIC ACIDS RESEARCH

Efficient Reverse Transcription Using Locked Nucleic Acid Nucleotides towards the Evolution of Nuclease Resistant RNA Aptamers

(2012) Lucile Crouzier et al.   PLoS One

Rapid One-Step Selection Method for Generating Nucleic Acid Aptamers: Development of a DNA Aptamer against α-Bungarotoxin

(2012) Lasse H. Lauridsen et al.   PLoS One

Aptamers and the next generation of diagnostic reagents

(2012) Varatharasa Thiviyanathan et al.   Proteomics Clinical Applications

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

Synthetic Genetic Polymers Capable of Heredity and Evolution

(2012) V. B. Pinheiro et al.   SCIENCE

A primer-free method that selects high-affinity single-stranded DNA aptamers using thermostable RNA ligase

(2011) Yi-Tak Lai et al.   ANALYTICAL BIOCHEMISTRY

Fluorescence detection of thrombin using autocatalytic strand displacement cycle reaction and a dual-aptamer DNA sandwich assay

(2011) Shuyan Niu et al.   ANALYTICAL BIOCHEMISTRY

Amplification, Mutation, and Sequencing of a Six-Letter Synthetic Genetic System

(2011) Zunyi Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RNA aptamers that functionally interact with green fluorescent protein and its derivatives

(2011) Bo Shui et al.   NUCLEIC ACIDS RESEARCH

Unlocking Biomarker Discovery: Large Scale Application of Aptamer Proteomic Technology for Early Detection of Lung Cancer

(2011) Rachel M. Ostroff et al.   PLoS One

Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery

(2011) Larry Gold et al.   PLoS One

Emulsion PCR: A High Efficient Way of PCR Amplification of Random DNA Libraries in Aptamer Selection

(2011) Keke Shao et al.   PLoS One

Probing the SELEX Process with Next-Generation Sequencing

(2011) Tatjana Schütze et al.   PLoS One

Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration

(2011) H. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleotide Bias Observed with a Short SELEX RNA Aptamer Library

(2011) William H. Thiel et al.   Nucleic Acid Therapeutics

Sensitive Discrimination and Detection of Prion Disease-Associated Isoform with a Dual-Aptamer Strategy by Developing a Sandwich Structure of Magnetic Microparticles and Quantum Dots

(2010) Sai Jin Xiao et al.   ANALYTICAL CHEMISTRY

Effect of 3′-end capping of aptamer with various 2′,4′-bridged nucleotides: Enzymatic post-modification toward a practical use of polyclonal aptamers

(2010) Yuuya Kasahara et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Click chemistry with DNA

(2010) Afaf H. El-Sagheer et al.   CHEMICAL SOCIETY REVIEWS

Enhanced Functional Potential of Nucleic Acid Aptamer Libraries Patterned to Increase Secondary Structure

(2010) Karen M. Ruff et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Screening and Improvement of an Anti-VEGF DNA Aptamer

(2010) Yoshihiko Nonaka et al.   MOLECULES

Computational generation and screening of RNA motifs in large nucleotide sequence pools

(2010) Namhee Kim et al.   NUCLEIC ACIDS RESEARCH

Monitoring Genomic Sequences during SELEX Using High-Throughput Sequencing: Neutral SELEX

(2010) Bob Zimmermann et al.   PLoS One

Computational approaches toward the design of pools for the in vitro selection of complex aptamers

(2010) X. Luo et al.   RNA

Targeting cancer cells with nucleic acid aptamers

(2010) Laura Cerchia et al.   TRENDS IN BIOTECHNOLOGY

Effective isolation of RNA aptamer through suppression of PCR bias

(2009) Shoutaro Tsuji et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Disease-specific biomarker discovery by aptamers

(2009) Henning Ulrich et al.   CYTOMETRY PART A

Aptamers as inhibitors of target proteins

(2009) S Missailidis et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

The stability of the circulating human proteome to variations in sample collection and handling procedures measured with an aptamer-based proteomics array

(2009) Rachel Ostroff et al.   Journal of Proteomics

Selection and elution of aptamers using nanoporous sol-gel arrays with integrated microheaters

(2009) Seung-min Park et al.   LAB ON A CHIP

The Shorter the Better: Reducing Fixed Primer Regions of Oligonucleotide Libraries for Aptamer Selection

(2009) Weihua Pan et al.   MOLECULES

Upgrading SELEX Technology by Using Lambda Exonuclease Digestion for Single-Stranded DNA Generation

(2009) Meltem Avci-Adali et al.   MOLECULES

Development of universal antidotes to control aptamer activity

(2009) Sabah Oney et al.   NATURE MEDICINE

Selection of DNA aptamers using atomic force microscopy

(2009) Yusuke Miyachi et al.   NUCLEIC ACIDS RESEARCH

In silico selection of RNA aptamers

(2009) Y. Chushak et al.   NUCLEIC ACIDS RESEARCH

Streptavidin-Coated Magnetic Beads for DNA Strand Separation Implicate a Multitude of Problems During Cell-SELEX

(2009) Angela Paul et al.   OLIGONUCLEOTIDES

Micromagnetic selection of aptamers in microfluidic channels

(2009) X. Lou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human growth hormone-specific aptamer identification using improved oligonucleotide ligand evolution method

(2009) Pınar Çalık et al.   PROTEIN EXPRESSION AND PURIFICATION

Synergistic effect of aptamers that inhibit exosites 1 and 2 on thrombin

(2009) S. M. Nimjee et al.   RNA

Minimal primer and primer-free SELEX protocols for selection of aptamers from random DNA libraries

(2008) Weihua Pan et al.   BIOTECHNIQUES

Electrochemically Protected Copper(I)-Catalyzed Azide-Alkyne Cycloaddition

(2008) Vu Hong et al.   CHEMBIOCHEM

SELEX with modified nucleotides

(2008) Anthony D Keefe et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Bioinformatic Analysis of the Contribution of Primer Sequences to Aptamer Structures

(2008) Matthew C. Cowperthwaite et al.   JOURNAL OF MOLECULAR EVOLUTION

Aptamer-Facilitated Biomarker Discovery (AptaBiD)

(2008) Maxim V. Berezovski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selecting Aptamers for a Glycoprotein through the Incorporation of the Boronic Acid Moiety

(2008) Minyong Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Vitro Selection and Characterization of Cellulose-Binding RNA Aptamers Using isothermal Amplification

(2008) B. J. Boese et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS