Quantitative evaluation of first, second, and third generation hairpin systems reveals the limit of mammalian vector-based RNAi

The Menu of Features that Define Primary MicroRNAs and Enable De Novo Design of MicroRNA Genes

(2015) Wenwen Fang et al.   MOLECULAR CELL

A Computational Algorithm to Predict shRNA Potency

(2014) Simon R.V. Knott et al.   MOLECULAR CELL

RNAi screening comes of age: improved techniques and complementary approaches

(2014) Stephanie E. Mohr et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

5′ isomiR variation is of functional and evolutionary importance

(2014) Geok Chin Tan et al.   NUCLEIC ACIDS RESEARCH

Deep Sequencing Insights in Therapeutic shRNA Processing and siRNA Target Cleavage Precision

(2014) Hubert Denise et al.   Molecular Therapy-Nucleic Acids

Beyond Secondary Structure: Primary-Sequence Determinants License Pri-miRNA Hairpins for Processing

(2013) Vincent C. Auyeung et al.   CELL

Stable RNA interference rules for silencing

(2013) Christof Fellmann et al.   NATURE CELL BIOLOGY

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

An Optimized microRNA Backbone for Effective Single-Copy RNAi

(2013) Christof Fellmann et al.   Cell Reports

The Loop Position of shRNAs and Pre-miRNAs Is Critical for the Accuracy of Dicer Processing In Vivo

(2012) Shuo Gu et al.   CELL

The effects of stem length and core placement on shRNA activity

(2011) Glen J Mcintyre et al.   BMC MOLECULAR BIOLOGY

Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay

(2011) Christof Fellmann et al.   MOLECULAR CELL

Polymerase II Promoter Strength Determines Efficacy of microRNA Adapted shRNAs

(2011) Robert Jan Lebbink et al.   PLoS One

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Rapid creation and quantitative monitoring of high coverage shRNA libraries

(2009) Michael C Bassik et al.   NATURE METHODS

Argonaute Loading Improves the 5′ Precision of Both MicroRNAs and Their miRNA∗ Strands in Flies

(2008) Hervé Seitz et al.   CURRENT BIOLOGY

Applications of Lentiviral Vectors for shRNA Delivery and Transgenesis

(2008) Oded Singer et al.   CURRENT GENE THERAPY

A simplified miRNA-based gene silencing method for Drosophila melanogaster

(2008) Benjamin Haley et al.   DEVELOPMENTAL BIOLOGY

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: Implications for the therapeutic development of RNAi

(2008) J. L. McBride et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minimizing variables among hairpin-based RNAi vectors reveals the potency of shRNAs

(2008) R. L. Boudreau et al.   RNA