标题
Effect of IL-17 receptor A blockade with brodalumab in inflammatory diseases
作者
关键词
-
出版物
RHEUMATOLOGY
Volume 55, Issue suppl 2, Pages ii43-ii55
出版商
Oxford University Press (OUP)
发表日期
2016-10-12
DOI
10.1093/rheumatology/kew346
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials
- (2015) Christopher E M Griffiths et al. LANCET
- Phase 3 Studies Comparing Brodalumab with Ustekinumab in Psoriasis
- (2015) Mark Lebwohl et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Human IL-17F/IL-17A Heterodimeric Cytokine Signals through the IL-17RA/IL-17RC Receptor Complex
- (2014) J. F. Wright et al. JOURNAL OF IMMUNOLOGY
- Identification of Functional Roles for Both IL-17RB and IL-17RA in Mediating IL-25-Induced Activities
- (2014) E. A. Rickel et al. JOURNAL OF IMMUNOLOGY
- TH17 Cells Mediate Steroid-Resistant Airway Inflammation and Airway Hyperresponsiveness in Mice
- (2014) L. McKinley et al. JOURNAL OF IMMUNOLOGY
- Gene Expression Profiles Normalized in Psoriatic Skin by Treatment with Brodalumab, a Human Anti-IL-17 Receptor Monoclonal Antibody
- (2014) C. B. Russell et al. JOURNAL OF IMMUNOLOGY
- Brodalumab, an Anti-IL17RA Monoclonal Antibody, in Psoriatic Arthritis
- (2014) Philip J. Mease et al. NEW ENGLAND JOURNAL OF MEDICINE
- Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials
- (2014) Richard G. Langley et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial
- (2013) Iain B McInnes et al. ANNALS OF THE RHEUMATIC DISEASES
- The anti-IL-17A antibody secukinumab does not attenuate ozone-induced airway neutrophilia in healthy volunteers
- (2013) A. Kirsten et al. EUROPEAN RESPIRATORY JOURNAL
- A Randomized, Double-Blind, Placebo-Controlled, Multiple-Dose Study to Evaluate the Safety, Tolerability, and Efficacy of Brodalumab (AMG 827) in Subjects with Moderate to Severe Asthma
- (2013) William W. Busse et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Keratinocyte Overexpression of IL-17C Promotes Psoriasiform Skin Inflammation
- (2013) A. Johnston et al. JOURNAL OF IMMUNOLOGY
- Cross-Study Homogeneity of Psoriasis Gene Expression in Skin across a Large Expression Range
- (2013) Jeannette Bigler et al. PLoS One
- Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study
- (2012) Mark C Genovese et al. ANNALS OF THE RHEUMATIC DISEASES
- Secukinumab induction and maintenance therapy in moderate-to-severe plaque psoriasis: a randomised, double-blind, placebo-controlled, phase II regimen-finding study
- (2012) P. Rich et al. BRITISH JOURNAL OF DERMATOLOGY
- Efficacy and safety of secukinumab in the treatment of moderate-to-severe plaque psoriasis: a randomized, double-blind, placebo-controlled phase II dose-ranging study
- (2012) K.A. Papp et al. BRITISH JOURNAL OF DERMATOLOGY
- Mo2083 A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Efficacy of AMG 827 in Subjects With Moderate to Severe Crohn's Disease
- (2012) Stephan R. Targan et al. GASTROENTEROLOGY
- Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial
- (2012) Wolfgang Hueber et al. GUT
- IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis
- (2012) James G. Krueger et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Autocrine-regulated airway smooth muscle cell migration is dependent on IL-17–induced growth-related oncogenes
- (2012) Laila A. Al-Alwan et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- IL-17 and TNF- Sustain Neutrophil Recruitment during Inflammation through Synergistic Effects on Endothelial Activation
- (2012) G. K. Griffin et al. JOURNAL OF IMMUNOLOGY
- Anti-IL-17 Receptor Antibody AMG 827 Leads to Rapid Clinical Response in Subjects with Moderate to Severe Psoriasis: Results from a Phase I, Randomized, Placebo-Controlled Trial
- (2012) Kim A. Papp et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction
- (2012) Makoto Kudo et al. NATURE MEDICINE
- Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathology
- (2012) Bryan C Petersen et al. NATURE MEDICINE
- Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis
- (2012) Kim A. Papp et al. NEW ENGLAND JOURNAL OF MEDICINE
- Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis
- (2012) Craig Leonardi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interleukin-17C Promotes Th17 Cell Responses and Autoimmune Disease via Interleukin-17 Receptor E
- (2011) Seon Hee Chang et al. IMMUNITY
- Mast Cells and Neutrophils Release IL-17 through Extracellular Trap Formation in Psoriasis
- (2011) A. M. Lin et al. JOURNAL OF IMMUNOLOGY
- Spondyloarthritis
- (2011) Maxime Dougados et al. LANCET
- Control of TH17 cells occurs in the small intestine
- (2011) Enric Esplugues et al. NATURE
- IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens
- (2011) Xinyang Song et al. NATURE IMMUNOLOGY
- Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF)
- (2011) Dongxu Sun et al. NATURE IMMUNOLOGY
- IL-17C regulates the innate immune function of epithelial cells in an autocrine manner
- (2011) Vladimir Ramirez-Carrozzi et al. NATURE IMMUNOLOGY
- LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study
- (2010) M. C. Genovese et al. ARTHRITIS AND RHEUMATISM
- The increased mucosal mRNA expressions of complement C3 and interleukin-17 in inflammatory bowel disease
- (2010) T. Sugihara et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Genetic variations associated with psoriasis and psoriatic arthritis found by genome-wide association
- (2010) Kristina Callis Duffin et al. Dermatologic Therapy
- The IL-17 Family Cytokines in Immunity and Disease
- (2010) Rajita Pappu et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1 , and TNF- Recapitulates Some Features of Psoriasis
- (2010) K. Guilloteau et al. JOURNAL OF IMMUNOLOGY
- Critical Role of IL-25 in Nematode Infection-Induced Alterations in Intestinal Function
- (2010) A. Zhao et al. JOURNAL OF IMMUNOLOGY
- IL-1RL2 and Its Ligands Contribute to the Cytokine Network in Psoriasis
- (2010) H. Blumberg et al. JOURNAL OF IMMUNOLOGY
- Assessment of the Psoriatic Transcriptome in a Large Sample: Additional Regulated Genes and Comparisons with In Vitro Models
- (2010) Johann E. Gudjonsson et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Integrative Responses to IL-17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis
- (2010) Andrea Chiricozzi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
- (2010) Eva Ellinghaus et al. NATURE GENETICS
- Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis
- (2010) Ulrike Hüffmeier et al. NATURE GENETICS
- Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma
- (2010) Stephane Lajoie et al. NATURE IMMUNOLOGY
- Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis
- (2010) W. Hueber et al. Science Translational Medicine
- Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease
- (2009) Kai Wang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis
- (2009) J T Elder GENES AND IMMUNITY
- Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses
- (2009) Harumichi Ishigame et al. IMMUNITY
- TH17-associated cytokines (IL-17A and IL-17F) in severe asthma
- (2009) Wisam Al-Ramli et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes
- (2009) Lisa C. Zaba et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- IL-17 Regulates CXCL1 mRNA Stability via an AUUUA/Tristetraprolin-Independent Sequence
- (2009) S. Datta et al. JOURNAL OF IMMUNOLOGY
- Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways
- (2009) Rajan P Nair et al. NATURE GENETICS
- Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides
- (2008) Camilla Jandus et al. ARTHRITIS AND RHEUMATISM
- Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways
- (2008) K.E. Nograles et al. BRITISH JOURNAL OF DERMATOLOGY
- T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ
- (2008) Xuexian O. Yang et al. IMMUNITY
- Regulation of inflammatory responses by IL-17F
- (2008) Xuexian O. Yang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Guidelines of care for the management of psoriasis and psoriatic arthritis
- (2008) Alice Gottlieb et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
- (2008) Jeffrey C Barrett et al. NATURE GENETICS
- Type I Interferon: Potential Therapeutic Target for Psoriasis?
- (2008) Yihong Yao et al. PLoS One
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More