Cardiac electrical defects in progeroid mice and Hutchinson–Gilford progeria syndrome patients with nuclear lamina alterations

Constitutive Intracellular Na+Excess in Purkinje Cells Promotes Arrhythmogenesis at Lower Levels of Stress Than Ventricular Myocytes From Mice With Catecholaminergic Polymorphic Ventricular TachycardiaCLINICAL PERSPECTIVE

(2016) B. Cicero Willis et al.   CIRCULATION

Ageing is associated with deterioration of calcium homeostasis in isolated human right atrial myocytes

(2015) Adela Herraiz-Martínez et al.   CARDIOVASCULAR RESEARCH

Targeting the late component of the cardiac L-type Ca2+current to suppress early afterdepolarizations

(2015) Roshni V. Madhvani et al.   JOURNAL OF GENERAL PHYSIOLOGY

Late Na+ current and protracted electrical recovery are critical determinants of the aging myopathy

(2015) Sergio Signore et al.   Nature Communications

Progeria: A Paradigm for Translational Medicine

(2014) Leslie B. Gordon et al.   CELL

Impact of Farnesylation Inhibitors on Survival in Hutchinson-Gilford Progeria Syndrome

(2014) Leslie B. Gordon et al.   CIRCULATION

Incidence of and Risk Factors for Sick Sinus Syndrome in the General Population

(2014) Paul N. Jensen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Defective Extracellular Pyrophosphate Metabolism Promotes Vascular Calcification in a Mouse Model of Hutchinson-Gilford Progeria Syndrome That Is Ameliorated on Pyrophosphate Treatment

(2013) Ricardo Villa-Bellosta et al.   CIRCULATION

Ambulatory ECG-Based T-Wave Alternans Monitoring for Risk Assessment and Guiding Medical Therapy: Mechanisms and Clinical Applications

(2013) Richard L. Verrier et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Mouse models of laminopathies

(2012) Haoyue Zhang et al.   AGING CELL

Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency

(2012) Marina Cerrone et al.   CARDIOVASCULAR RESEARCH

Actin Cytoskeleton Rest Stops Regulate Anterograde Traffic of Connexin 43 Vesicles to the Plasma Membrane

(2012) James W. Smyth et al.   CIRCULATION RESEARCH

Human ZMPSTE24 disease mutations: residual proteolytic activity correlates with disease severity

(2012) Jemima Barrowman et al.   HUMAN MOLECULAR GENETICS

Cell autonomous and systemic factors in progeria development: Figure 1.

(2011) Fernando G. Osorio et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Functional consequences of abnormal Cx43 expression in the heart

(2011) Magda S.C. Fontes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Aging-Associated Cardiovascular Changes and Their Relationship to Heart Failure

(2011) James B. Strait et al.   Heart Failure Clinics

Cardiovascular Pathology in Hutchinson-Gilford Progeria: Correlation With the Vascular Pathology of Aging

(2010) Michelle Olive et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Cardiac Desmosome and Arrhythmogenic Cardiomyopathies

(2010) Mario Delmar et al.   CIRCULATION RESEARCH

SYMPOSIUM REVIEW: Revealing the structural basis of action of hERG potassium channel activators and blockers

(2010) Matthew Perry et al.   JOURNAL OF PHYSIOLOGY-LONDON

Role of A-type lamins in signaling, transcription, and chromatin organization

(2009) Vicente Andrés et al.   JOURNAL OF CELL BIOLOGY

Phenotype and Course of Hutchinson–Gilford Progeria Syndrome

(2008) Melissa A. Merideth et al.   NEW ENGLAND JOURNAL OF MEDICINE