Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome

Single-molecule imaging of non-equilibrium molecular ensembles on the millisecond timescale

(2016) Manuel F Juette et al.   NATURE METHODS

Structure of the mammalian antimicrobial peptide Bac7(1–16) bound within the exit tunnel of a bacterial ribosome

(2016) A. Carolin Seefeldt et al.   NUCLEIC ACIDS RESEARCH

Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association

(2016) T. Sprink et al.   Science Advances

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structure of the E. coli ribosome–EF-Tu complex at

(2015) Niels Fischer et al.   NATURE

Transport domain unlocking sets the uptake rate of an aspartate transporter

(2015) Nurunisa Akyuz et al.   NATURE

High-resolution structure of the Escherichia coli ribosome

(2015) Jonas Noeske et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9-Å resolution

(2015) Stefan Arenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insights into species-specific features of the ribosome from the pathogenStaphylococcus aureus

(2015) Zohar Eyal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Bacillus subtilis 70S ribosome reveals the basis for species-specific stalling

(2015) Daniel Sohmen et al.   Nature Communications

High-resolution structure of the Escherichia coli ribosome

(2015) Jonas Noeske et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Synergy of Streptogramin Antibiotics Occurs Independently of Their Effects on Translation

(2014) Jonas Noeske et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The bright future of single-molecule fluorescence imaging

(2014) Manuel F Juette et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Drug Sensing by the Ribosome Induces Translational Arrest via Active Site Perturbation

(2014) Stefan Arenz et al.   MOLECULAR CELL

Translational stalling at polyproline stretches is modulated by the sequence context upstream of the stall site

(2014) Agata L. Starosta et al.   NUCLEIC ACIDS RESEARCH

Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide

(2014) Stefan Arenz et al.   Nature Communications

Myosin VIII associates with microtubule ends and together with actin plays a role in guiding plant cell division

(2014) Shu-Zon Wu et al.   eLife

Tools for Characterizing Bacterial Protein Synthesis Inhibitors

(2013) Cédric Orelle et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ultra-stable organic fluorophores for single-molecule research

(2013) Qinsi Zheng et al.   CHEMICAL SOCIETY REVIEWS

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

Ribosome-targeting antibiotics and mechanisms of bacterial resistance

(2013) Daniel N. Wilson   NATURE REVIEWS MICROBIOLOGY

Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor

(2013) A. Simonetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new understanding of the decoding principle on the ribosome

(2012) Natalia Demeshkina et al.   NATURE

Structural basis of highly conserved ribosome recycling in eukaryotes and archaea

(2012) Thomas Becker et al.   NATURE

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

Differential Effects of Thiopeptide and Orthosomycin Antibiotics on Translational GTPases

(2011) Aleksandra Mikolajka et al.   CHEMISTRY & BIOLOGY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Conformational Sampling of Aminoacyl-tRNA during Selection on the Bacterial Ribosome

(2010) Peter Geggier et al.   JOURNAL OF MOLECULAR BIOLOGY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Mitigating Unwanted Photophysical Processes for Improved Single-Molecule Fluorescence Imaging

(2009) Richa Dave et al.   BIOPHYSICAL JOURNAL

The A–Z of bacterial translation inhibitors

(2009) Daniel N. Wilson   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

A fast dynamic mode of the EF-G-bound ribosome

(2009) James B Munro et al.   EMBO JOURNAL

GTPase activation of elongation factor EF-Tu by the ribosome during decoding

(2009) Jan-Christian Schuette et al.   EMBO JOURNAL

The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA

(2009) T. M. Schmeing et al.   SCIENCE

Sharpening high resolution information in single particle electron cryomicroscopy

(2008) J.J. Fernández et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structure of the 30S translation initiation complex

(2008) Angelita Simonetti et al.   NATURE