标题
Holdase activity of secreted Hsp70 masks amyloid-β42 neurotoxicity inDrosophila
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 113, Issue 35, Pages E5212-E5221
出版商
Proceedings of the National Academy of Sciences
发表日期
2016-08-17
DOI
10.1073/pnas.1608045113
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Modeling the complex pathology of Alzheimer's disease in Drosophila
- (2015) Pedro Fernandez-Funez et al. EXPERIMENTAL NEUROLOGY
- Anti-Aβ single-chain variable fragment antibodies exert synergistic neuroprotective activities inDrosophilamodels of Alzheimer's disease
- (2015) Pedro Fernandez-Funez et al. HUMAN MOLECULAR GENETICS
- Mutations in the substrate binding site of human heat-shock protein 70 indicate specific interaction with HLA-DR outside the peptide binding groove
- (2014) Karin M. Rohrer et al. IMMUNOLOGY
- Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases
- (2014) Jing L Guo et al. NATURE MEDICINE
- Extracellular Chaperones and Proteostasis
- (2013) Amy R. Wyatt et al. Annual Review of Biochemistry
- Extracellular chaperones prevent Aβ42-induced toxicity in rat brains
- (2013) Roberta Cascella et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Genetics of dementia
- (2013) Clement T Loy et al. LANCET
- Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
- (2013) Mathias Jucker et al. NATURE
- Drosophila Models of Proteinopathies: the Little Fly that Could
- (2012) CURRENT PHARMACEUTICAL DESIGN
- Roles of Extracellular Chaperones in Amyloidosis
- (2012) Amy R. Wyatt et al. JOURNAL OF MOLECULAR BIOLOGY
- The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
- (2012) Iryna Benilova et al. NATURE NEUROSCIENCE
- Chaperones in autophagy
- (2012) Susmita Kaushik et al. PHARMACOLOGICAL RESEARCH
- Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers
- (2012) B. Mannini et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The ER stress factor XBP1s prevents amyloid-β neurotoxicity
- (2011) Sergio Casas-Tinto et al. HUMAN MOLECULAR GENETICS
- Characterization of Oligomer Formation of Amyloid-β Peptide Using a Split-luciferase Complementation Assay
- (2011) Tadafumi Hashimoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Suppression of Alzheimer's Disease-Related Phenotypes by Expression of Heat Shock Protein 70 in Mice
- (2011) T. Hoshino et al. JOURNAL OF NEUROSCIENCE
- SignalP 4.0: discriminating signal peptides from transmembrane regions
- (2011) Thomas Nordahl Petersen et al. NATURE METHODS
- Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases
- (2011) Daniel W. Neef et al. NATURE REVIEWS DRUG DISCOVERY
- Activation of JNK Signaling Mediates Amyloid-ß-Dependent Cell Death
- (2011) Meghana Tare et al. PLoS One
- Molecular mechanisms of neurodegeneration in Alzheimer's disease
- (2010) L. Crews et al. HUMAN MOLECULAR GENETICS
- Cellular strategies for controlling protein aggregation
- (2010) Jens Tyedmers et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Prion-like transmission of protein aggregates in neurodegenerative diseases
- (2010) Patrik Brundin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The role of molecular chaperones in human misfolding diseases
- (2009) Sarah A. Broadley et al. FEBS LETTERS
- The amyloid hypothesis for Alzheimer’s disease: a critical reappraisal
- (2009) John Hardy JOURNAL OF NEUROCHEMISTRY
- In Vivo Generation of Neurotoxic Prion Protein: Role for Hsp70 in Accumulation of Misfolded Isoforms
- (2009) Pedro Fernandez-Funez et al. PLoS Genetics
- The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases
- (2008) Konstanze F Winklhofer et al. EMBO JOURNAL
- Neuronal assemblies of theDrosophila mushroom body
- (2008) Nobuaki K. Tanaka et al. JOURNAL OF COMPARATIVE NEUROLOGY
- BRI2 (ITM2b) Inhibits A Deposition In Vivo
- (2008) J. Kim et al. JOURNAL OF NEUROSCIENCE
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