Activation and conformational dynamics of a class B G-protein-coupled glucagon receptor
出版年份 2016 全文链接
标题
Activation and conformational dynamics of a class B G-protein-coupled glucagon receptor
作者
关键词
-
出版物
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
Volume 18, Issue 18, Pages 12642-12650
出版商
Royal Society of Chemistry (RSC)
发表日期
2016-04-04
DOI
10.1039/c6cp00798h
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Markov State Models Provide Insights into Dynamic Modulation of Protein Function
- (2015) Diwakar Shukla et al. ACCOUNTS OF CHEMICAL RESEARCH
- ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
- (2015) James A. Maier et al. Journal of Chemical Theory and Computation
- An insight into antagonist binding and induced conformational dynamics of class B GPCR corticotropin-releasing factor receptor 1
- (2015) Junli Xu et al. Molecular BioSystems
- Quercetin Enhances Cisplatin Sensitivity of Human Osteosarcoma Cells by Modulating microRNA-217-KRAS Axis
- (2015) Xian Zhang et al. MOLECULES AND CELLS
- Understanding the conformation transition in the activation pathway of β2 adrenergic receptor via a targeted molecular dynamics simulation
- (2015) Xiuchan Xiao et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Accelerated molecular dynamics simulations of ligand binding to a muscarinic G-protein-coupled receptor
- (2015) Kalli Kappel et al. QUARTERLY REVIEWS OF BIOPHYSICS
- Conformational states of the full-length glucagon receptor
- (2015) Linlin Yang et al. Nature Communications
- Lipid14: The Amber Lipid Force Field
- (2014) Callum J. Dickson et al. Journal of Chemical Theory and Computation
- Exploration of the antagonist CP-376395 escape pathway for the corticotropin-releasing factor receptor 1 by random acceleration molecular dynamics simulations
- (2014) Qifeng Bai et al. Molecular BioSystems
- Free energy landscape of G-protein coupled receptors, explored by accelerated molecular dynamics
- (2014) Yinglong Miao et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Simulations of Biased Agonists in the β2 Adrenergic Receptor with Accelerated Molecular Dynamics
- (2013) Irina G. Tikhonova et al. BIOCHEMISTRY
- Mapping of Allosteric Druggable Sites in Activation-Associated Conformers of the M2 Muscarinic Receptor
- (2013) Yinglong Miao et al. Chemical Biology & Drug Design
- Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor
- (2013) Susmith Mukund et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of the human glucagon class B G-protein-coupled receptor
- (2013) Fai Yiu Siu et al. NATURE
- Molecular signatures of G-protein-coupled receptors
- (2013) A. J. Venkatakrishnan et al. NATURE
- Activation and dynamic network of the M2 muscarinic receptor
- (2013) Y. Miao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Insights into the structure of class B GPCRs
- (2013) Kaspar Hollenstein et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Structure and activation of rhodopsin
- (2012) X Edward Zhou et al. ACTA PHARMACOLOGICA SINICA
- Differential determinants for coupling of distinct G proteins with the class B secretin receptor
- (2012) Gene L. Garcia et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Structure-Function of the G Protein–Coupled Receptor Superfamily
- (2012) Vsevolod Katritch et al. Annual Review of Pharmacology and Toxicology
- NetworkView: 3D display and analysis of protein{middle dot}RNA interaction networks
- (2012) J. Eargle et al. BIOINFORMATICS
- Mapping Structural Determinants within Third Intracellular Loop That Direct Signaling Specificity of Type 1 Corticotropin-releasing Hormone Receptor
- (2012) Anu Punn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Routine Access to Millisecond Time Scale Events with Accelerated Molecular Dynamics
- (2012) Levi C.T. Pierce et al. Journal of Chemical Theory and Computation
- Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies
- (2012) S. Vohra et al. Journal of the Royal Society Interface
- H++ 3.0: automating pK prediction and the preparation of biomolecular structures for atomistic molecular modeling and simulations
- (2012) R. Anandakrishnan et al. NUCLEIC ACIDS RESEARCH
- Targeting the glucagon receptor family for diabetes and obesity therapy
- (2012) Young Min Cho et al. PHARMACOLOGY & THERAPEUTICS
- Molecular basis for negative regulation of the glucagon receptor
- (2012) C. M. Koth et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- GPCR activation: a mutagenic spotlight on crystal structures
- (2012) Edward C. Hulme TRENDS IN PHARMACOLOGICAL SCIENCES
- The Role of Conformational Ensembles in Ligand Recognition in G-Protein Coupled Receptors
- (2011) Michiel J. M. Niesen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Analysis of the glucagon receptor first extracellular loop by the substituted cysteine accessibility method
- (2011) David J. Roberts et al. PEPTIDES
- Studying functional dynamics in bio-molecules using accelerated molecular dynamics
- (2011) Phineus R. L. Markwick et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Activation mechanism of the 2-adrenergic receptor
- (2011) R. O. Dror et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutational and Cysteine Scanning Analysis of the Glucagon Receptor N-terminal Domain
- (2010) Martine Prévost et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- G protein-coupled receptors: novel targets for drug discovery in cancer
- (2010) Rosamaria Lappano et al. NATURE REVIEWS DRUG DISCOVERY
- Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor
- (2009) Christina Rye Underwood et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dynamical networks in tRNA:protein complexes
- (2009) A. Sethi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Passing the baton in class B GPCRs: peptide hormone activation via helix induction?
- (2009) Christoph Parthier et al. TRENDS IN BIOCHEMICAL SCIENCES
- Structural diversity of G protein-coupled receptors and significance for drug discovery
- (2008) Malin C. Lagerström et al. NATURE REVIEWS DRUG DISCOVERY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation