Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies

Differential determinants for coupling of distinct G proteins with the class B secretin receptor

(2012) Gene L. Garcia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

G-protein-coupled receptor dynamics: dimerization and activation models compared with experiment

(2012) Bruck Taddese et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The role of the extracellular loops of the CGRP receptor, a family B GPCR

(2012) James Barwell et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Evolution of Class A G-Protein-Coupled Receptors: Implications for Molecular Modeling

(2012) M. Chabbert et al.   CURRENT MEDICINAL CHEMISTRY

Mapping Structural Determinants within Third Intracellular Loop That Direct Signaling Specificity of Type 1 Corticotropin-releasing Hormone Receptor

(2012) Anu Punn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the agonist-bound neurotensin receptor

(2012) Jim F. White et al.   NATURE

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

(2012) Aashish Manglik et al.   NATURE

Structure-Based Discovery of Allosteric Modulators of Two Related Class B G-Protein-Coupled Receptors

(2011) Chris de Graaf et al.   ChemMedChem

Molecular Basis of Secretin Docking to Its Intact Receptor Using Multiple Photolabile Probes Distributed throughout the Pharmacophore

(2011) Maoqing Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Progress in Structure Based Drug Design for G Protein-Coupled Receptors

(2011) Miles Congreve et al.   JOURNAL OF MEDICINAL CHEMISTRY

Residues within the Transmembrane Domain of the Glucagon-Like Peptide-1 Receptor Involved in Ligand Binding and Receptor Activation: Modelling the Ligand-Bound Receptor

(2011) K. Coopman et al.   MOLECULAR ENDOCRINOLOGY

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Analysis of the glucagon receptor first extracellular loop by the substituted cysteine accessibility method

(2011) David J. Roberts et al.   PEPTIDES

Modeling GPCR active state conformations: The β2-adrenergic receptor

(2011) Lisa M. Simpson et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structural insights into RAMP modification of secretin family G protein-coupled receptors: implications for drug development

(2011) Julia K. Archbold et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Secretin Occupies a Single Protomer of the Homodimeric Secretin Receptor Complex

(2010) Maoqing Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence that Interaction between Conserved Residues in Transmembrane Helices 2, 3, and 7 Are Crucial for Human VPAC1 Receptor Activation

(2010) A. O. Chugunov et al.   MOLECULAR PHARMACOLOGY

Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism

(2010) Ernst ter Haar et al.   STRUCTURE

Passing the baton in class B GPCRs: peptide hormone activation via helix induction?

(2009) Christoph Parthier et al.   TRENDS IN BIOCHEMICAL SCIENCES

Crystal structure of opsin in its G-protein-interacting conformation

(2008) Patrick Scheerer et al.   NATURE

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY