标题
The global spectrum of protein-coding pharmacogenomic diversity
作者
关键词
-
出版物
PHARMACOGENOMICS JOURNAL
Volume 18, Issue 1, Pages 187-195
出版商
Springer Nature
发表日期
2016-10-25
DOI
10.1038/tpj.2016.77
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Genetic variation among 82 pharmacogenes: The PGRNseq data from the eMERGE network
- (2016) WS Bush et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Analysis of protein-coding genetic variation in 60,706 humans
- (2016) Monkol Lek et al. NATURE
- Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences
- (2016) Greyson P Twist et al. npj Genomic Medicine
- Genomewide Association Study of Tacrolimus Concentrations in African American Kidney Transplant Recipients Identifies MultipleCYP3A5Alleles
- (2015) W. S. Oetting et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Cypiripi: exact genotyping ofCYP2D6using high-throughput sequencing data
- (2015) Ibrahim Numanagić et al. BIOINFORMATICS
- Comparison of GENCODE and RefSeq gene annotation and the impact of reference geneset on variant effect prediction
- (2015) Adam Frankish et al. BMC GENOMICS
- Pharmacogenetic Markers of Drug Efficacy and Toxicity
- (2015) VLM Yip et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity
- (2015) Munir Pirmohamed et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- Genetic variation in the human cytochrome P450 supergene family
- (2015) Kohei Fujikura et al. Pharmacogenetics and Genomics
- Analyzing the potential for incorrect haplotype calls with different pharmacogenomic assays in different populations: a simulation based on 1000 Genomes data
- (2015) Matthias Samwald et al. PHARMACOGENOMICS
- Unravelling the transcriptomic landscape of the major phase II UDP-glucuronosyltransferase drug metabolizing pathway using targeted RNA sequencing
- (2015) A Tourancheau et al. PHARMACOGENOMICS JOURNAL
- Role of SLC22A1 polymorphic variants in drug disposition, therapeutic responses and drug–drug interactions
- (2015) C Arimany-Nardi et al. PHARMACOGENOMICS JOURNAL
- Achieving high-sensitivity for clinical applications using augmented exome sequencing
- (2015) Anil Patwardhan et al. Genome Medicine
- Whole genome sequencing in pharmacogenomics
- (2015) Theodora Katsila et al. Frontiers in Pharmacology
- The emerging era of pharmacogenomics: current successes, future potential, and challenges
- (2014) J.W. Lee et al. CLINICAL GENETICS
- Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update
- (2014) K R Crews et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Considerations for rare variants in drug metabolism genes and the clinical implications
- (2014) Britt I Drögemöller et al. Expert Opinion on Drug Metabolism & Toxicology
- Genetic Variants Associated With Phenytoin-Related Severe Cutaneous Adverse Reactions
- (2014) Wen-Hung Chung et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Ancestry estimation and control of population stratification for sequence-based association studies
- (2014) Chaolong Wang et al. NATURE GENETICS
- Establishment of CYP2D6 reference samples by multiple validated genotyping platforms
- (2014) H Fang et al. PHARMACOGENOMICS JOURNAL
- OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin
- (2014) Ligong Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Choice of transcripts and software has a large effect on variant annotation
- (2014) Davis J McCarthy et al. Genome Medicine
- Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population
- (2014) Elaine T. Lim et al. PLoS Genetics
- Influence of Cytochrome P450 (CYP) 3A4*1G Polymorphism on the Pharmacokinetics of Tacrolimus, Probability of Acute Cellular Rejection, and mRNA Expression Level of CYP3A5 Rather than CYP3A4 in Living-Donor Liver Transplant Patients
- (2013) Miwa Uesugi et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Ethical and legal implications of whole genome and whole exome sequencing in African populations
- (2013) Galen EB Wright et al. BMC Medical Ethics
- Why do hypertensive patients of African ancestry respond better to calciumblockers and diuretics than to ACE inhibitors and β-adrenergic blockers? Asystematic review
- (2013) Lizzy M Brewster et al. BMC Medicine
- Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Carbamazepine Dosing
- (2013) S G Leckband et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Genetic variants at 4q21, 4q23 and 12q24 are associated with esophageal squamous cell carcinoma risk in a Chinese population
- (2013) Yong Gao et al. HUMAN GENETICS
- Sequencing studies in human genetics: design and interpretation
- (2013) David B. Goldstein et al. NATURE REVIEWS GENETICS
- Next-generation sequencing of pharmacogenes
- (2013) Britt I. Drögemöller et al. Pharmacogenetics and Genomics
- Pharmacogenomics, ancestry and clinical decision making for global populations
- (2013) E Ramos et al. PHARMACOGENOMICS JOURNAL
- Higher frequency of genetic variants conferring increased risk for ADRs for commonly used drugs treating cancer, AIDS and tuberculosis in persons of African descent
- (2013) F Aminkeng et al. PHARMACOGENOMICS JOURNAL
- Characterization of the genetic variation present in CYP3A4 in three South African populations
- (2013) Britt Drögemöller et al. Frontiers in Genetics
- Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants
- (2012) Wenqing Fu et al. NATURE
- An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People
- (2012) M. R. Nelson et al. SCIENCE
- A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes
- (2012) D. G. MacArthur et al. SCIENCE
- Whole-genome resequencing in pharmacogenomics: moving away from past disparities to globally representative applications
- (2011) Britt I Drögemöller et al. PHARMACOGENOMICS
- Long-term persistence with statin therapy: A nationwide register study in Finland
- (2009) Arja Helin-Salmivaara et al. CLINICAL THERAPEUTICS
- Functional Variants in ADH1B and ALDH2 Coupled With Alcohol and Smoking Synergistically Enhance Esophageal Cancer Risk
- (2009) Ri Cui et al. GASTROENTEROLOGY
- Pharmacogenetic variation at CYP2C9, CYP2C19, and CYP2D6 at global and microgeographic scales
- (2009) Johanna Sistonen et al. Pharmacogenetics and Genomics
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started