An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People
出版年份 2012 全文链接
标题
An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People
作者
关键词
-
出版物
SCIENCE
Volume 337, Issue 6090, Pages 100-104
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2012-05-18
DOI
10.1126/science.1217876
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- fastsimcoal: a continuous-time coalescent simulator of genomic diversity under arbitrarily complex evolutionary scenarios
- (2011) Laurent Excoffier et al. BIOINFORMATICS
- GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease
- (2011) Bradley E Aouizerat et al. BMC Cardiovascular Disorders
- The GENCODE exome: sequencing the complete human exome
- (2011) Alison J Coffey et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Genomics for the world
- (2011) Carlos D. Bustamante et al. NATURE
- Variation in genome-wide mutation rates within and between human families
- (2011) Donald F Conrad et al. NATURE GENETICS
- How informative is a negative finding in a small pharmacogenetic study?
- (2011) S-A Bacanu et al. PHARMACOGENOMICS JOURNAL
- Demographic history and rare allele sharing among human populations
- (2011) S. Gravel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Emergence of Genome-Based Drug Repositioning
- (2011) Y. A. Lussier et al. Science Translational Medicine
- Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data
- (2011) Joanne H Wang et al. Genome Medicine
- Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project
- (2011) Guillaume Lettre et al. PLoS Genetics
- The functional spectrum of low-frequency coding variation
- (2011) Gabor T Marth et al. GENOME BIOLOGY
- Rare Deletions at 16p13.11 Predispose to a Diverse Spectrum of Sporadic Epilepsy Syndromes
- (2010) Erin L. Heinzen et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Direct Measure of the De Novo Mutation Rate in Autism and Schizophrenia Cohorts
- (2010) Philip Awadalla et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Pooled Association Tests for Rare Variants in Exon-Resequencing Studies
- (2010) Alkes L. Price et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Rare Variant Association Analysis Methods for Complex Traits
- (2010) Jennifer Asimit et al. Annual Review of Genetics
- Genome-Wide Association Scan of Trait Depression
- (2010) Antonio Terracciano et al. BIOLOGICAL PSYCHIATRY
- Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study
- (2010) Dalia Kasperavičiūtė et al. BRAIN
- Loss-of-function variants in the genomes of healthy humans
- (2010) D. G. MacArthur et al. HUMAN MOLECULAR GENETICS
- Lack of Association Between the Trp719Arg Polymorphism in Kinesin-Like Protein-6 and Coronary Artery Disease in 19 Case-Control Studies
- (2010) Themistocles L. Assimes et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- A map of human genome variation from population-scale sequencing
- (2010) Richard M. Durbin et al. NATURE
- Variants in FAM13A are associated with chronic obstructive pulmonary disease
- (2010) Michael H Cho et al. NATURE GENETICS
- Missing heritability and strategies for finding the underlying causes of complex disease
- (2010) Evan E. Eichler et al. NATURE REVIEWS GENETICS
- The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics
- (2010) J. A. Blake et al. NUCLEIC ACIDS RESEARCH
- A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder
- (2010) Ke-Sheng Wang et al. SCHIZOPHRENIA RESEARCH
- Deep resequencing reveals excess rare recent variants consistent with explosive population growth
- (2010) Alex Coventry et al. Nature Communications
- Modification of Multiple Sclerosis Phenotypes by African Ancestry at HLA
- (2009) Bruce A. C. Cree et al. ARCHIVES OF NEUROLOGY
- Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci
- (2009) Charlotte Vignal et al. ARTHRITIS AND RHEUMATISM
- The PsyCoLaus study: methodology and characteristics of the sample of a population-based survey on psychiatric disorders and their association with genetic and cardiovascular risk factors
- (2009) Martin Preisig et al. BMC Psychiatry
- Measuring the Rates of Spontaneous Mutation From Deep and Large-Scale Polymorphism Data
- (2009) Philipp W. Messer GENETICS
- SNP detection for massively parallel whole-genome resequencing
- (2009) R. Li et al. GENOME RESEARCH
- Finding the missing heritability of complex diseases
- (2009) Teri A. Manolio et al. NATURE
- Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
- (2009) Melanie Bahlo et al. NATURE GENETICS
- Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
- (2009) Philip L De Jager et al. NATURE GENETICS
- Genome-wide Linkage and Association Analyses to Identify Genes Influencing Adiponectin Levels: The GEMS Stud
- (2009) Hua Ling et al. Obesity
- Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
- (2009) L. A. Hindorff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci
- (2009) Sreekumar G. Pillai et al. PLoS Genetics
- Estimating the Single Nucleotide Polymorphism Genotype Misclassification From Routine Double Measurements in a Large Epidemiologic Sample
- (2008) I. M. Heid et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- The Population Reference Sample, POPRES: A Resource for Population, Disease, and Pharmacological Genetics Research
- (2008) Matthew R. Nelson et al. AMERICAN JOURNAL OF HUMAN GENETICS
- ADZE: a rarefaction approach for counting alleles private to combinations of populations
- (2008) Z. A. Szpiech et al. BIOINFORMATICS
- SOAP: short oligonucleotide alignment program
- (2008) R. Li et al. BIOINFORMATICS
- The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome
- (2008) Mathieu Firmann et al. BMC Cardiovascular Disorders
- Correlation between Genetic and Geographic Structure in Europe
- (2008) Oscar Lao et al. CURRENT BIOLOGY
- Natural Selection on Genes that Underlie Human Disease Susceptibility
- (2008) Ran Blekhman et al. CURRENT BIOLOGY
- Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE)
- (2008) J. Vestbo et al. EUROPEAN RESPIRATORY JOURNAL
- Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis
- (2008) Sergio E. Baranzini et al. HUMAN MOLECULAR GENETICS
- Population-based linkage analysis of schizophrenia and bipolar case–control cohorts identifies a potential susceptibility locus on 19q13
- (2008) C Francks et al. MOLECULAR PSYCHIATRY
- Genome-wide association study of recurrent major depressive disorder in two European case–control cohorts
- (2008) P Muglia et al. MOLECULAR PSYCHIATRY
- Genomewide association for schizophrenia in the CATIE study: results of stage 1
- (2008) P F Sullivan et al. MOLECULAR PSYCHIATRY
- Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides
- (2008) Jaspal S Kooner et al. NATURE GENETICS
- InterPro: the integrative protein signature database
- (2008) S. Hunter et al. NUCLEIC ACIDS RESEARCH
- Genome-Wide Analysis of Single Nucleotide Polymorphisms Uncovers Population Structure in Northern Europe
- (2008) Elina Salmela et al. PLoS One
- Candidate Single-Nucleotide Polymorphisms From a Genomewide Association Study of Alzheimer Disease
- (2007) Hao Li et al. ARCHIVES OF NEUROLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now