Enantiomeric Cyclic Peptides with Different Caco-2 Permeability Suggest Carrier-Mediated Transport
出版年份 2015 全文链接
标题
Enantiomeric Cyclic Peptides with Different Caco-2 Permeability Suggest Carrier-Mediated Transport
作者
关键词
-
出版物
CHEMISTRY-A EUROPEAN JOURNAL
Volume 21, Issue 22, Pages 8023-8027
出版商
Wiley
发表日期
2015-04-28
DOI
10.1002/chem.201501270
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cell-Permeable Cyclic Peptides from Synthetic Libraries Inspired by Natural Products
- (2015) William M. Hewitt et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Macrocycles: lessons from the distant past, recent developments, and future directions
- (2015) Andrei K. Yudin Chemical Science
- Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable
- (2014) Daniel S. Nielsen et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Mucus as a Barrier to Drug Delivery - Understanding and Mimicking the Barrier Properties
- (2014) Marie Boegh et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Tools and rules for macrocycles
- (2014) Christian Heinis Nature Chemical Biology
- Rational design and synthesis of an orally bioavailable peptide guided by NMR amide temperature coefficients
- (2014) Conan K. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed
- (2014) Timothy A. Hill et al. ACS Medicinal Chemistry Letters
- Form and Function in Cyclic Peptide Natural Products: A Pharmacokinetic Perspective
- (2013) Andrew T. Bockus et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Future directions for peptide therapeutics development
- (2013) Allan A. Kaspar et al. DRUG DISCOVERY TODAY
- Approaches for enhancing oral bioavailability of peptides and proteins
- (2013) Jwala Renukuntla et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Macrocyclic Drugs and Clinical Candidates: What Can Medicinal Chemists Learn from Their Properties?
- (2013) Fabrizio Giordanetto et al. JOURNAL OF MEDICINAL CHEMISTRY
- Getting in Shape: Controlling Peptide Bioactivity and Bioavailability Using Conformational Constraints
- (2012) Jonathan E. Bock et al. ACS Chemical Biology
- N-Methylation of Peptides and Proteins: An Important Element for Modulating Biological Functions
- (2012) Jayanta Chatterjee et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The Future of Peptide-based Drugs
- (2012) David J. Craik et al. Chemical Biology & Drug Design
- Intestinal Permeability of Cyclic Peptides: Common Key Backbone Motifs Identified
- (2012) Johannes G. Beck et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Parallel Artificial Membrane Permeability Assay (PAMPA) - Is it Better than Caco-2 for Human Passive Permeability Prediction?
- (2012) J. M. Reis et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Synthesis of N-methylated cyclic peptides
- (2012) Jayanta Chatterjee et al. Nature Protocols
- Pharmaceutical drug transport: the issues and the implications that it is essentially carrier-mediated only
- (2011) Douglas B. Kell et al. DRUG DISCOVERY TODAY
- Drug-permeability and transporter assays in Caco-2 and MDCK cell lines
- (2011) Donna A Volpe Future Medicinal Chemistry
- The Effect of Multiple N-Methylation on Intestinal Permeability of Cyclic Hexapeptides
- (2011) Oded Ovadia et al. MOLECULAR PHARMACEUTICS
- On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds
- (2011) Tina R White et al. Nature Chemical Biology
- Lipophilicity in drug discovery
- (2010) Michael J Waring Expert Opinion on Drug Discovery
- Coexistence of passive and carrier-mediated processes in drug transport
- (2010) Kiyohiko Sugano et al. NATURE REVIEWS DRUG DISCOVERY
- Synthesis of chemically modified bioactive peptides: recent advances, challenges and developments for medicinal chemistry
- (2009) Soledad Royo Gracia et al. Future Medicinal Chemistry
- N-Methylation of Peptides: A New Perspective in Medicinal Chemistry
- (2008) Jayanta Chatterjee et al. ACCOUNTS OF CHEMICAL RESEARCH
- Improving Oral Bioavailability of Peptides by Multiple N-Methylation: Somatostatin Analogues
- (2008) Eric Biron et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- LogD: Lipophilicity for ionisable compounds
- (2008) Melanie Kah et al. CHEMOSPHERE
- Artificial Membrane Assays to Assess Permeability
- (2008) Bernard Faller CURRENT DRUG METABOLISM
- Permeability for Intestinal Absorption: Caco-2 Assay and Related Issues
- (2008) Barry Press et al. CURRENT DRUG METABOLISM
- Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?
- (2008) Paul D. Dobson et al. NATURE REVIEWS DRUG DISCOVERY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now