Synthesis of N-methylated cyclic peptides

Cilengitide: The First Anti-Angiogenic Small Molecule Drug Candidate. Design, Synthesis and Clinical Evaluation

(2011) Carlos Mas-Moruno et al.   Anti-Cancer Agents in Medicinal Chemistry

The Effect of Multiple N-Methylation on Intestinal Permeability of Cyclic Hexapeptides

(2011) Oded Ovadia et al.   MOLECULAR PHARMACEUTICS

Contemporary strategies for peptide macrocyclization

(2011) Christopher J. White et al.   Nature Chemistry

Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis

(2011) Young-Woo Kim et al.   Nature Protocols

N-Methylated sst2 Selective Somatostatin Cyclic Peptide Analogue as a Potent Candidate for Treating Neurogenic Inflammation

(2011) Jayanta Chatterjee et al.   ACS Medicinal Chemistry Letters

Improvement of drug-like properties of peptides: the somatostatin paradigm

(2010) Oded Ovadia et al.   Expert Opinion on Drug Discovery

Mutremdamide A and Koshikamides C−H, Peptide Inhibitors of HIV-1 Entry from DifferentTheonellaSpecies

(2010) Alberto Plaza et al.   JOURNAL OF ORGANIC CHEMISTRY

MultipleN-Methylation of MT-II Backbone Amide Bonds Leads to Melanocortin Receptor Subtype hMC1R Selectivity: Pharmacological and Conformational Studies

(2010) Lucas Doedens et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Solid-phase synthesis of short α-helices stabilized by the hydrogen bond surrogate approach

(2010) Anupam Patgiri et al.   Nature Protocols

Anticonvulsant Met-Enkephalin Analogues Containing Backbone Spacers Reveal Alternative Non-Opioid Signaling in the Brain

(2009) Hee-Kyoung Lee et al.   ACS Chemical Biology

N-Methylation of Peptides: A New Perspective in Medicinal Chemistry

(2008) Jayanta Chatterjee et al.   ACCOUNTS OF CHEMICAL RESEARCH

Improving Oral Bioavailability of Peptides by Multiple N-Methylation: Somatostatin Analogues

(2008) Eric Biron et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Backbone Cyclic Peptidomimetic Melanocortin-4 Receptor Agonist as a Novel Orally Administrated Drug Lead for Treating Obesity

(2008) Shmuel Hess et al.   JOURNAL OF MEDICINAL CHEMISTRY

CanN-methylated amino acids serve as substitutes for prolines in conformational design of cyclic pentapeptides?

(2008) Burkhardt Laufer et al.   JOURNAL OF PEPTIDE SCIENCE

Conformational Preference and Potential Templates ofN-Methylated Cyclic Pentaalanine Peptides

(2007) Jayanta Chatterjee et al.   CHEMISTRY-A EUROPEAN JOURNAL