On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds

The Effect of Multiple N-Methylation on Intestinal Permeability of Cyclic Hexapeptides

(2011) Oded Ovadia et al.   MOLECULAR PHARMACEUTICS

Expanding the range of ‘druggable’ targets with natural product-based libraries: an academic perspective

(2010) Renato A Bauer et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

MultipleN-Methylation of MT-II Backbone Amide Bonds Leads to Melanocortin Receptor Subtype hMC1R Selectivity: Pharmacological and Conformational Studies

(2010) Lucas Doedens et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of serum lipids on the pharmacokinetics of atazanavir in hyperlipidemic rats

(2009) Keizo Fukushima et al.   BIOMEDICINE & PHARMACOTHERAPY

N-Methylation of Peptides: A New Perspective in Medicinal Chemistry

(2008) Jayanta Chatterjee et al.   ACCOUNTS OF CHEMICAL RESEARCH

Improving Oral Bioavailability of Peptides by Multiple N-Methylation: Somatostatin Analogues

(2008) Eric Biron et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Long-Term Pharmacokinetic Efficacy and Safety of Low-Dose Ritonavir as a Booster and Atazanavir Pharmaceutical Formulation Based on Solid Dispersion System in Rats

(2008) Keizo Fukushima et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The exploration of macrocycles for drug discovery — an underexploited structural class

(2008) Edward M. Driggers et al.   NATURE REVIEWS DRUG DISCOVERY